Frontiers in Pain Research

Original Research

Published on 20 Feb 2026

Receiving preferred treatments may improve low back pain outcomes: a non-randomized comparative study

in Musculoskeletal Pain

Tareq I. Alshyab
Ahmad Alrawashdeh
Nizar Mohammad Audat
Khader A. Almhdawi
Alaa Oteir
Zaid Aldahamsheh
Mohammad A. Bani Hani
Saddam F. Kanaan

Frontiers in Pain Research

doi 10.3389/fpain.2026.1687883

112 views

Brief Research Report

Accepted on 19 Feb 2026

Pride and Pain – A Lifespan-Informed, Identity-Affirming Approach to Paediatric Pain in 2SLGBTQIA+ Youth: Panel Discussion at the International Symposium for Pediatric Pain

in Pediatric Pain

Jaris Paul Swidrovich
Emre Ilhan
Katelynn Boerner
Lauren Elisabeth Harrison

Frontiers in Pain Research

Clinical Trial

Accepted on 19 Feb 2026

Topical RM191A gel for chronic peripheral neuropathic pain: randomized, double-blind, placebo-controlled, crossover pilot study

in Pharmacological Treatment of Pain

Paul Glare
Charles Brooker
Andrew D. Weiss
Daniel Saverio John Costa
Sofia Casbolt
Llewellyn Casbolt

Frontiers in Pain Research

Hypothesis and Theory

Published on 18 Feb 2026

Variational free energy as a conceptual framework for understanding habituation in spinal cord stimulation

in Neuromodulatory Interventions

Alexander Taghva

Frontiers in Pain Research

doi 10.3389/fpain.2026.1728339

154 views

Original Research

Accepted on 17 Feb 2026

EDIN and N-PASS pain scale comparison in asphyxiated newborns treated with therapeutic hypothermia

in Pediatric Pain

Licia Lugli
Elisabetta Garetti
Maria Federica Roversi
Arianna Bianchini
Riccardo Cuoghi Costantini
Isotta Guidotti
Michele De Novellis
Eugenio Spaggiari
Paola Lago
ALBERTO BERARDI

Frontiers in Pain Research

Original Research

Accepted on 16 Feb 2026

Artemin/GFRA3 Axis and TRP channels: Molecular Insights from a Feline Model of Osteoarthritis

in Pain Mechanisms

Joshua Wheeler
Chie Mochizuki
Margaret Elizabeth Gruen
B. Duncan X. Lascelles
Santosh K. Mishra

Frontiers in Pain Research

Mini Review

Accepted on 16 Feb 2026

Platelet-Rich Plasma for Treatment of Knee Osteoarthritis: A Narrative Review

in Pain Mechanisms

Samuel L. Patton
Kelsey Gustafson
Matt Castinado
Usman Latif
Dawood Sayed
Talal Khan
Christopher M Lam

Frontiers in Pain Research

Systematic Review

Accepted on 16 Feb 2026

Methodological Quality and Measurement Properties of Traditional Chinese Medicine Syndrome Assessment Scales for Cardiovascular Diseases: A COSMIN-Based Systematic Review

in Clinical Trials, Methods, and Evidence Synthesis

佩晓范
Hong Chen
Xiaoxue Lan
Zhuxin Mao
Zhihui Chen
Meng Song
易梁
Yanan Sun
Changhe Yu
Ruijin Qiu

Frontiers in Pain Research

Systematic Review

Accepted on 16 Feb 2026

Impact of therapeutic exercises on pain-related outcomes in patients with knee osteoarthritis: an umbrella review of 116 systematic reviews

in Musculoskeletal Pain

Dmitriy Viderman
Sultan Kalikanov
Akerke Mazhibiyeva
Alua Shagirova
Malika Toleubekova
Mina Aubakirova
Yerkin G. Abdildin

Frontiers in Pain Research

Original Research

Accepted on 13 Feb 2026

A Tonic Electrocutaneous Stimulation Paradigm for Graded Sensory C-Fiber Engagement in Healthy Subjects

in Pain Research Methods

Youngsun Kong
Andrew Peitzsch
Riley McNaboe
I-Ping Chen
Ki Chon

Frontiers in Pain Research

Original Research

Published on 13 Feb 2026

Participant perspectives on a multimodal program for neuropathic pain after spinal cord injury

in Non-Pharmacological Treatment of Pain

Meredith Pinkerton
Roberta Vastano
Kim D. Anderson
Marlon Wong
Gabriel Fernandez
Eva Widerström-Noga

Frontiers in Pain Research

doi 10.3389/fpain.2026.1755081

355 views

Original Research

Published on 13 Feb 2026

Phantom limb telescoping in individuals with limb loss: links to anxiety, depression, and pain-related measures

in Non-Pharmacological Treatment of Pain

Andrea Aternali
Heather Lumsden-Ruegg
Lora Appel
Sander L. Hitzig
Amanda L. Mayo
Joel Katz

Frontiers in Pain Research

doi 10.3389/fpain.2026.1755884

422 views

Original Research

Published on 13 Feb 2026

High impact chronic pain in children: exploration of associated characteristics and clinical factors in children and parents

in Pediatric Pain

Ulla Caverius
Marcelo Rivano Fischer
Jan Lexell
Sophia Åkerblom

Frontiers in Pain Research

doi 10.3389/fpain.2026.1744974

273 views

Perspective

Accepted on 12 Feb 2026

The importance of partnership in chronic pain – co-creation of tomorrow's pain care by working together in research, implementation, and knowledge dissemination

in Non-Pharmacological Treatment of Pain

Paulin Andréll
Birgit Heckemann
Anna Grimby Ekman
Gunilla Göran
Marie-Louise Olsson
Roger Johansson
Paula Forslund
Axel Wolf

Frontiers in Pain Research

Opinion

Published on 12 Feb 2026

Updating UK clinical guidelines to incorporate the placebo effect in peri-operative care: challenges and opportunities

in Pharmacological Treatment of Pain

Emma Gregory

Frontiers in Pain Research

doi 10.3389/fpain.2026.1638970

440 views

Mini Review

Accepted on 11 Feb 2026

Non-Pharmacological Approaches for Migraine Management: A mini-Review

in Headache

Vineeta Singh
Anand Kumar
Sucharita Ray
Kamalesh Chakravarty
Neha Lall
Deepika Joshi

Frontiers in Pain Research

147 views

Perspective

Accepted on 10 Feb 2026

Shaping the future of abdominal and pelvic pain research with novel scientific and technological advances

in Abdominal and Pelvic Pain

Anna P Malykhina

Frontiers in Pain Research

Systematic Review

Accepted on 09 Feb 2026

Dexmedetomidine Versus Midazolam-Fentanyl for Intraoperative Analgesia and Sedation: A systematic review and meta analysis

in Pharmacological Treatment of Pain

Hashim Talib Hashim
Mostafa.A Khalifa
Aya Ahmed Shimal
Mohamed H. Elbadawi
Khadeeja Ali Hamzah
Abdulhadi M. A. Mahgoub
Alaa R. AL-Ihribat
Salem Waleed Salem Mohamed
Fathima Raahima Riyas Mohamed
Elian khalafalla

Frontiers in Pain Research

Review

Published on 09 Feb 2026

Behavioral assessment of pain in rodents: advances from evoked responses to spontaneous states and multimodal approaches

in Pain Research Methods

Meiqi Li
Yongxin Bao
Mingsen Chen

Frontiers in Pain Research

doi 10.3389/fpain.2026.1739384

320 views

Original Research

Accepted on 06 Feb 2026

Association of Analgesic Pharmacological Effect with Pain Site in Pediatric Oncology Patients

in Pediatric Pain

Flavia Carvalho Marotta
Eduardo Ladeia Leal
Isabelle Alvarenga Oliveira
Thuane Sales Gonçalves
Silmara Rodrigues Machado
Carolina Paula Jesus Kasa
Paulo Caleb J L Santos

Frontiers in Pain Research

Original Research

Accepted on 06 Feb 2026

Manual Therapy Improves Pain and Walking Function in geriatric Knee Osteoarthritis via Proprioceptive Mediation

in Non-Pharmacological Treatment of Pain

Bowen Zhu
Sipeng Huang
Shuaipan Zhang
Qingguang Zhu
Min Fang

Frontiers in Pain Research

Original Research

Accepted on 06 Feb 2026

Integrated Multi-omics Elucidates the Dual Anti-inflammatory and Neuroendocrine Mechanisms of Novel TCM Plasters against Primary Dysmenorrhea

in Abdominal and Pelvic Pain

Weihui Liang
Cao Wenxuan
Yuan Zheng
Li Tie
Aoxue Yu
Fuchun Wang
Jia Liu

Frontiers in Pain Research

Mini Review

Published on 06 Feb 2026

Decoding chronic pain: integrating genetics, neuroimaging, and AI for precision management

in Pain Mechanisms

Bade Uckac
Natalia S. Ogonowski
Luis M. García-Marín
Santiago Diaz-Torres
Scott F. Farrell
Dale R. Nyholt
Miguel E. Rentería

Frontiers in Pain Research

doi 10.3389/fpain.2026.1747942

410 views

Original Research

Published on 05 Feb 2026

OPRM1 gene polymorphism linked to anxiety in cancer-related pain patients: an observational study

in Cancer Pain

Jianwen Mo
Zhuolun Xie
Xiaolan Li
Lei Hu
Min Chen
Xiaolin Xia
Wei Wang

Frontiers in Pain Research

doi 10.3389/fpain.2026.1666510

349 views

945 articles

articles

Receiving preferred treatments may improve low back pain outcomes: a non-randomized comparative study

Pride and Pain – A Lifespan-Informed, Identity-Affirming Approach to Paediatric Pain in 2SLGBTQIA+ Youth: Panel Discussion at the International Symposium for Pediatric Pain

Topical RM191A gel for chronic peripheral neuropathic pain: randomized, double-blind, placebo-controlled, crossover pilot study

Variational free energy as a conceptual framework for understanding habituation in spinal cord stimulation

EDIN and N-PASS pain scale comparison in asphyxiated newborns treated with therapeutic hypothermia

Artemin/GFRA3 Axis and TRP channels: Molecular Insights from a Feline Model of Osteoarthritis

Platelet-Rich Plasma for Treatment of Knee Osteoarthritis: A Narrative Review

Methodological Quality and Measurement Properties of Traditional Chinese Medicine Syndrome Assessment Scales for Cardiovascular Diseases: A COSMIN-Based Systematic Review

Impact of therapeutic exercises on pain-related outcomes in patients with knee osteoarthritis: an umbrella review of 116 systematic reviews

A Tonic Electrocutaneous Stimulation Paradigm for Graded Sensory C-Fiber Engagement in Healthy Subjects

Participant perspectives on a multimodal program for neuropathic pain after spinal cord injury

Phantom limb telescoping in individuals with limb loss: links to anxiety, depression, and pain-related measures

High impact chronic pain in children: exploration of associated characteristics and clinical factors in children and parents

The importance of partnership in chronic pain – co-creation of tomorrow's pain care by working together in research, implementation, and knowledge dissemination

Updating UK clinical guidelines to incorporate the placebo effect in peri-operative care: challenges and opportunities

Non-Pharmacological Approaches for Migraine Management: A mini-Review

Shaping the future of abdominal and pelvic pain research with novel scientific and technological advances

Dexmedetomidine Versus Midazolam-Fentanyl for Intraoperative Analgesia and Sedation: A systematic review and meta analysis

Behavioral assessment of pain in rodents: advances from evoked responses to spontaneous states and multimodal approaches

Association of Analgesic Pharmacological Effect with Pain Site in Pediatric Oncology Patients

Manual Therapy Improves Pain and Walking Function in geriatric Knee Osteoarthritis via Proprioceptive Mediation

Integrated Multi-omics Elucidates the Dual Anti-inflammatory and Neuroendocrine Mechanisms of Novel TCM Plasters against Primary Dysmenorrhea

Decoding chronic pain: integrating genetics, neuroimaging, and AI for precision management

OPRM1 gene polymorphism linked to anxiety in cancer-related pain patients: an observational study