CORRECTION article

Front. Pediatr., 18 December 2018

Sec. Neonatology

Volume 6 - 2018 | https://doi.org/10.3389/fped.2018.00399

Corrigendum: Epinephrine Use During Newborn Resuscitation

  • Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX, United States

In the original article, there was a typographical error in Table 1, as published. The endotracheal (ET) epinephrine dose should be “0.05–0.1 mg/kg.” In Table 1, it was mistakenly written as “0.05–1 mg/kg.” The corrected Table 1 appears below.

Table 1

RouteDoseSummary of evidence
Intravenous0.01–0.03 mg/kg
  • Preferred route and appear to be more efficacious than other routes

  • Dose extrapolated from adult experience

  • High dose epinephrine offers no advantage and is associated with increased post-resuscitation adverse effects and increased mortality

  • Dose escalation studies in neonatal animal model with transition physiology are urgently needed

Endotracheal (ET)0.05–0.1 mg/kg
  • Less effective than IV route

  • Achieved plasma concentration is less and it peaks slower with ET epinephrine compared to IV epinephrine

  • Can be used until IV access is available

Intraosseous0.01–0.03 mg/kg
  • Limited evidence compared to IV route

  • Providers frequently involved in newborn resuscitation feel more comfortable with rapid UVC insertion compared to IO route

IntramuscularNot recommended
  • Very limited evidence

  • Significant tissue damage at local site

Epinephrine use during newborn resuscitation: route, dose, and summary of evidence.

The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.

Summary

Keywords

epinephrine, neonatal resuscitation, asphyxia, newborn, delivery room, infants

Citation

Kapadia VS and Wyckoff MH (2018) Corrigendum: Epinephrine Use During Newborn Resuscitation. Front. Pediatr. 6:399. doi: 10.3389/fped.2018.00399

Received

12 November 2018

Accepted

30 November 2018

Published

18 December 2018

Volume

6 - 2018

Edited and reviewed by

Graeme R. Polglase, Monash University, Australia

Updates

Copyright

*Correspondence: Vishal S. Kapadia

This article was submitted to Neonatology, a section of the journal Frontiers in Pediatrics

Disclaimer

All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.

Cite article

Copy to clipboard


Export citation file


Share article

Article metrics