CASE REPORT article
Front. Pediatr.
Sec. Pediatric Pulmonology
Volume 13 - 2025 | doi: 10.3389/fped.2025.1559240
Use of extracorporeal support to treat a fulminant Mycobacterium bovis infection and complex broncho-oesophageal fistula in a child
Provisionally accepted
Hussein Hussein MRCP1
Richard Paget1Louis Grandjean1
Alasdar Bamford1Ashwin Pandey1Katy Fidler2Claire Snowden2
ARUN BEEMAN1
Pooja Shetty1
Nagarajan Muthialu1*- 1Great Ormond Street Hospital for Children NHS Foundation Trust, London, United Kingdom
- 2University Hospitals Sussex NHS Foundation Trust, Chichester, United Kingdom
Select one of your emails
You have multiple emails registered with Frontiers:
Notify me on publication
Please enter your email address:
If you already have an account, please login
You don't have a Frontiers account ? You can register here
Tuberculosis (TB), caused by Mycobacterium tuberculosis remains a significant public health issue. Human TB caused by Mycobacterium bovis (M. bovis) is rare accounting for less than 1% of TB cases in UK annually. Tuberculosis secondary to immunomodulating agents is well described. We present a case of airway and pulmonary TB caused by M. bovis, likely due to zoonotic transmission, in an immunocompromised child due to medical management of Crohn's disease.Management required extracorporeal membrane oxygenation for complex surgical interventions on airway and oesophagus.
Keywords: ECMO, Mycobacterium, Broncho-oesophageal fistula, Pneumonectomy, Oesophageal surgery
Received: 12 Jan 2025; Accepted: 18 Aug 2025.
Copyright: © 2025 MRCP, Paget, Grandjean, Bamford, Pandey, Fidler, Snowden, BEEMAN, Shetty and Muthialu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Nagarajan Muthialu, Great Ormond Street Hospital for Children NHS Foundation Trust, London, WC1N 3JH, United Kingdom
Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.