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CASE REPORT article

Front. Pediatr.

Sec. Neonatology

This article is part of the Research TopicAdvances and Challenges in Neonatal Surgery: Congenital and Acquired ConditionsView all 32 articles

Necrotizing Enterocolitis in a neonate with severe Congenital Pulmonary Valve Stenosis complicated by postoperative right Atrial Thrombus: A Case Report

Provisionally accepted
  • 1Department of Pediatrics, West China Second University Hospital, Sichuan University, Chengdu, Sichuan Province, China
  • 2Key Laboratory of Birth Defects and Related Diseases of Women and Children, West China Second University Hospital, Sichuan University, Chengdu, Sichuan Province, China

The final, formatted version of the article will be published soon.

Congenital heart disease may increase the incidence of necrotizing enterocolitis, especially in low-birth-weight infants. We report a case of a newborn with pulmonary valve stenosis who developed neonatal necrotizing enterocolitis IIIB. The infant underwent initial cardiac surgery followed by a laparotomy. After cardiac surgery, a right atrial thrombus was found by cardiac ultrasound. Enterococcus faecium was identified by metagenomic next-generation sequencing of ascitic fluid. The infant received targeted antibiotic therapy and anticoagulant treatment, and then discharged.

Keywords: Pulmonary Valve Stenosis, necrotizing enterocolitis, metagenomic next-generation sequencing, anticoagulation, case report

Received: 17 Mar 2025; Accepted: 07 Nov 2025.

Copyright: © 2025 Zhang, Zhang and Liu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence:
Li Zhang, zhanglihk@126.com
Haiting Liu, liuhaiting9@163.com

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