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ORIGINAL RESEARCH article

Front. Pediatr.

Sec. Pediatric Cardiology

This article is part of the Research TopicAdvancements in Congenital Heart Disease: Diagnosis and Management InnovationsView all 19 articles

Recent Efficacy of Modified Right Vertical Infra-Axillary Thoracotomy for Ventricular Septal Defects in Pediatric Patients with Younger Age and Low Body Weight

Provisionally accepted
Heqi  ZhangHeqi Zhang1Weijie  LiangWeijie Liang2*Hua  CaoHua Cao1Taibing  FanTaibing Fan1
  • 1Central China Fuwai Hospital of Zhengzhou University, Zhengzhou, China
  • 2Department of Cardiology, Fuwai Central China Cardiovascular Hospital, Zhengzhou, China

The final, formatted version of the article will be published soon.

Objective: To evaluate the safety and efficacy of a modified right vertical infra-axillary thoracotomy (MRVIAT) technique for treating ventricular septal defects (VSD) in infants younger than six months. and low body weight (≤5 kg). Methods: From January 2020 to December 2024,the study included 204 infants who underwent MRVIAT and 62 infants who underwent median sternotomy (MS). General, perioperative, and follow-up data were analyzed retrospectively. Results: Operation time, intraoperative bleeding, 24-hour postoperative chest tube drainage, mechanical ventilation time, postoperative intensive care unit time, extubation rate within 24 hours postoperatively, hospital costs, and incision length were shorter in the MRVIAT group than in the MS group (P < 0.05). Peak airway pressure, lung dynamic compliance (Cdyn), and oxygenation index were similar in both groups at preoperative and postoperative time points (P > 0.05). There were no deaths in either group, and there was no significant difference in complication rates (P > 0.05). At 60 months (with a median follow-up of 25 months), two cases of sternal deformity occurred in the MS group, but none occurred in the MRVIAT group. Conclusion: ventricular septal defect repair by MRVIAT in younger children with low body weight is less invasive. It provides good incision exposure, does not affect pulmonary function, reduces intraoperative bleeding and postoperative hospital stay and costs, and facilitates rapid recovery. This procedure is safe and effective and can be considered an alternative to median sternotomy.

Keywords: infants, Median sternotomy, modified right vertical infra-axillary thoracotomy, Pulmonary Function, Ventricular septal defects

Received: 11 Aug 2025; Accepted: 08 Dec 2025.

Copyright: © 2025 Zhang, Liang, Cao and Fan. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Weijie Liang

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