CASE REPORT article
Front. Pediatr.
Sec. Pediatric Gastroenterology, Hepatology and Nutrition
Unique Colonoscopic Manifestations in a Patient with Henoch-Schönlein Purpura: A Case Report of an Ileocecal Valve Ulcer
Provisionally accepted
- Yuebei People's Hospital, Shaoguan, China
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Ileocecal valve ulceration can arise from various causes, including infections, inflammatory bowel diseases, Behçet's disease, tumors and medications. We present a rare case of Henoch-Schönlein purpura (HSP)-associated ileocecal ulcer in a pediatric patient. The child initially presented with abdominal pain and subsequently developed extensive bilateral lower limb purpura on the third hospital day. Colonoscopic examination revealed erosions and shallow ulcerations localized to the ileocecal valve, with histopathological analysis revealing characteristic mucosal stromal edema and diffuse inflammatory cell infiltration. The patient exhibited marked clinical improvement following intravenous methylprednisolone pulse therapy. This case enriches the clinical spectrum of HSP and helps clinicians better understand its intestinal involvement.
Keywords: Henoch-Schönlein purpura (HSP), IgA vasculitis, Ileocecal valve ulcer, Abdominal Pain, Child‒Pugh patient
Received: 20 Oct 2025; Accepted: 26 Nov 2025.
Copyright: © 2025 Tan, Xiao and Deng. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Haizhi Tan
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