CASE REPORT article
Front. Pediatr.
Sec. Pediatric Endocrinology
This article is part of the Research TopicPerinatal and Post-Natal Life: Metabolism and Health Outcomes Volume IIView all articles
Neonatal Hyperthyroidism with myocardial injury: a case report
Provisionally accepted
- 1Zhenhai People's Hospital, Ningbo, China
- 2Department of Pediatrics, Ningbo Zhenhai People's Hospital, Ningbo, China
Select one of your emails
You have multiple emails registered with Frontiers:
Notify me on publication
Please enter your email address:
If you already have an account, please login
You don't have a Frontiers account ? You can register here
ABSTRACT Neonatal hyperthyroidism (NH) is a rarely reported condition, but inappropriate treatment can have serious consequences. Early diagnosis, treatment, and follow-up are, therefore, essential. We present the case of a male newborn who was admitted to the Pediatrics Department 24 minutes after birth due to prematurity, presenting with tachypnea and grunting for 20 minutes. Subsequently, the infant developed increased respiratory rate, tachycardia, crying, and irritability. Bilateral periorbital edema and hyperdynamic heart sounds were also noted. Myocardial injury markers were significantly elevated, indicating myocardial injury. Following treatment with dopamine and dobutamine, the heart rate decreased, but crying, irritability, and periorbital edema persisted. Further history-taking led to a diagnosis of NH with neonatal goiter. The infant was started on oral methimazole and propranolol. Three days after initiation of therapy, the symptoms resolved rapidly, and the patient was discharged.
Keywords: case report, Myocardial injury, Neonatal hyperthyroidism, pediatri c, therapy
Received: 15 Dec 2025; Accepted: 30 Jan 2026.
Copyright: © 2026 Tian, Jiang and Liu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Junhua Tian
Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.