Frontiers in Pharmacology

Original Research

Published on 30 Apr 2025

Antibacterial activity of tamoxifen derivatives against methicillin-resistant Staphylococcus aureus

in Pharmacology of Infectious Diseases

Irene Molina Panadero
Javier Falcón Torres
Abdelkrim Hmadcha
Salvatore Princiotto
Luigi Cutarella
Mattia Mori
Sabrina Dallavalle
Michael S. Christodoulou
Younes Smani

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1549288

222 views

Original Research

Published on 30 Apr 2025

Chemopreventive and therapeutic effects of Hippophae rhamnoides L. fruit peels evaluated in preclinical models of breast carcinoma

in Ethnopharmacology

Dana Dvorska
Dominika Sebova
Karol Kajo
Andrea Kapinova
Emil Svajdlenka
Michal Goga
Richard Frenak
Jakub Treml
Sandra Mersakova
Jan Strnadel

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1561436

108 views

Original Research

Published on 30 Apr 2025

Resveratrol attenuates the priapism phenotype in sickle cell mice by restoring NO-cGMP-PDE5 signaling and reducing NADPH oxidase 2 expression

in Ethnopharmacology

Carolina Oliveira Splendore
Tammyris Helena Rebecchi Silveira
Dalila Andrade Pereira
Beatriz Pereira Bossarino
Mariana Gonçalves de Oliveira
Fabiano Beraldi Calmasini
Arthur L. Burnett
Fernando Ferreira Costa
Fábio Henrique Silva

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1551533

138 views

Original Research

Published on 30 Apr 2025

Sulindac exhibits anti-proliferative and anti-invasive effects and enhances the sensitivity to paclitaxel in ovarian cancer

in Pharmacology of Anti-Cancer Drugs

Shuning Chen
Weimin Kong
Xiaochang Shen
Nikita Sinha
Jennifer Haag
Boer Deng
Haomeng Zhang
Catherine John
Wenchuan Sun
Chunxiao Zhou

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1520771

Original Research

Published on 30 Apr 2025

Association of serum insulin-like growth factor-1 and adrenocorticotropic hormone therapeutic response in patients with infantile epileptic spasms syndrome

in Neuropharmacology

Ka-Na Lin
Feng Han
Ying-Yan Wang
Wei Zhao
Ji-Wen Wang
Hao Li
Yun-Qing Zhou

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1599641

Review

Published on 30 Apr 2025

Nanotechnology-driven strategies in postoperative cancer treatment: innovations in drug delivery systems

in Pharmacology of Anti-Cancer Drugs

Jun-Jie Zhou
Yan-Chuan Feng
Min-Long Zhao
Qi Guo
Xi-Bo Zhao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1586948

105 views

Original Research

Published on 30 Apr 2025

Post-marketing safety of anakinra and canakinumab: a real-world pharmacovigilance study based on FDA adverse event reporting system

in Pharmacoepidemiology

Hao Liu
Wei Yan
Jinsong Li
Dezhi Yan
Di Luo

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1483669

102 views

Original Research

Published on 30 Apr 2025

Molecular pharmacokinetic mechanism of JBP485 against aristolochic acid I (AAI) -induced nephrotoxicity

in Drug Metabolism and Transport

Chong Wang
Huan Jin
Changyuan Wang
Jingjing Wu
Qiang Meng
Ming Zhong
Huijun Sun
Yuheng Wei
Ge Gao
Taiichi Kaku

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1577942

Original Research

Published on 30 Apr 2025

Regulating mitochondrial oxidative phosphorylation and MAPK signaling: wedelolactone as a novel therapeutic for radiation-induced thrombocytopenia

in Ethnopharmacology

Zhichao Li
Qinyao Li
Shuang Wu
Xinyue Mei
Xiao Qi
Sheng Liu
Gan Qiao
Hongping Shen
Jiesi Luo
Jing Zeng

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1508215

Original Research

Published on 30 Apr 2025

Resveratrol targeting MDM2/P53/PUMA axis to inhibit colonocyte apoptosis in DSS-induced ulcerative colitis mice

in Gastrointestinal and Hepatic Pharmacology

Rui Tang
Ling Jiang
Quan Ji
Pengyuan Kang
Yuan Liu
Pengyu Miao
Xiaofan Xu
Mingxi Tang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1572906

114 views

Original Research

Published on 30 Apr 2025

Antidepressant-like activity of Bezafibrate in mice models of depression: a behavioral and neurobiological characterization

in Neuropharmacology

Dawei Xu
Jin Zhou
Siyi Zhou
Weizhen Wang
Chengniu Wang
Bo Jiang
Wei Zhao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1595341

Original Research

Published on 30 Apr 2025

Menthacarin, a proprietary combination of peppermint and caraway oil, alters cultured human fecal microbiota composition, resulting in increased SCFA production

in Ethnopharmacology

Martin D. Lehner
Philippe Ulsemer
Sandra Christochowitz

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1569052

296 views

Original Research

Published on 30 Apr 2025

Drug-associated infections and infestations in older adults with tumor necrosis factor-alpha inhibitors: a real-world retrospective and pharmacovigilance study

in Pharmacoepidemiology

Xihui Yu
Jiahong Zhong
Xuemei Zhuang
Zhuomiao Lin
Hongbo Fu
Yaofeng Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1533902

129 views

Original Research

Published on 30 Apr 2025

Pulmonary artery-targeted low-dose metformin-loaded nanocapsules safely improve pulmonary arterial hypertension in rats

in Cardiovascular and Smooth Muscle Pharmacology

Ayako Chida-Nagai
Naoki Masaki
Hiroki Sato
Tatsuya Kato
Emi Takakuwa
Yoshihiro Matsuno
Atsushi Manabe
Atsuhito Takeda

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1577570

162 views

Correction

Accepted on 29 Apr 2025

Corrigendum: Protective Effects of Cordyceps militaris Against Hepatocyte Apoptosis and Liver Fibrosis Induced by High Palmitic Acid Diet

in Ethnopharmacology

Wan-Ting Tsai
Jiro Hasegawa Situmorang
Wei-Wen Kuo
Chia-Hua Kuo
Shinn-Zong Lin
Chih-Yang Huang
Tsung-Jung Ho

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1619149

Original Research

Accepted on 29 Apr 2025

Loss of SynDIG4/PRRT1 alters distribution of AMPA receptors in Rab4- and Rab11-positive endosomes and impairs basal AMPA receptor recycling

in Pharmacology of Ion Channels and Channelopathies

Chun-Wei He
Elva Diaz

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1568908