Frontiers in Pharmacology

Mini Review

Published on 11 Feb 2026

From dopamine to muscarine: xanomeline-trospium (KarXT) as a novel direction in the psychopharmacotherapy of schizophrenia

in Neuropharmacology

Kacper Żełabowski
Wojciech Pichowicz
Julia Dembowska
Maciej Szwajkowski
Daria Mykhailova
Grzegorz Wurm
Kamil Biedka
Katarzyna Błaszczyk
Patryk Piotrowski

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1774437

487 views

Systematic Review

Published on 11 Feb 2026

Efficacy and safety of traditional Chinese classic prescriptions combined with metformin in the treatment of type 2 diabetes mellitus: a Bayesian network meta-analysis

in Ethnopharmacology

Linlin Che
Wei Dong
Ya Liu
Hongwei Guo

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1693378

283 views

Case Report

Published on 11 Feb 2026

Platelet-rich plasma for the treatment of postoperative anastomotic fistula of the gastrointestinal tract: a case report

in Translational Pharmacology

Sihui Jia
Yawen Guo
Changkai Zhang
Xiaoyuan Sun
Licun Wang
Haiyan Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1727021

169 views

Review

Published on 11 Feb 2026

Plant polysaccharides in neuroprotection: mechanistic insights across central nervous system disorders

in Ethnopharmacology

Qiyue Yu
Hui Chen
Zhuofeng Qu
Jialin Qu
Yan Wang
Lina Liang
Shouyu Hu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1727705

268 views

Review

Published on 11 Feb 2026

Innate immune signalling, neuroinflammation and network plasticity in temporal lobe epilepsy

in Experimental Pharmacology and Drug Discovery

Oscar Arias-Carrión
Julieta Rodríguez de Ita
Philipp Yu

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1770964

256 views

Perspective

Published on 11 Feb 2026

Yttrium-90 radioembolization as an in vivo immune modulator: clinical evidence and pharmacologic implications

in Pharmacology of Anti-Cancer Drugs

Shiwei Tang
Jia Cai
Pandi Wu
Guanwu Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1770097

208 views

Review

Published on 11 Feb 2026

Oleaceae plants: a source of metabolites with atheroprotective potential

in Ethnopharmacology

Agnieszka Filipek
Edyta Czepielewska

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1721433

288 views

Original Research

Published on 11 Feb 2026

Regional absorption of talinolol mediated by intestinal transporters: insights from PBPK modeling analysis

in Drug Metabolism and Transport

Kazuya Ishida
Xiaomin Liang
Fulden Buyukozturk
Jia Hao
Christine Wan
Yurong Lai

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1726481

377 views

Original Research

Published on 11 Feb 2026

LYVE-1 identifies asthma and drives PDGF-BB-induced proliferation, migration, and oxidative stress in airway smooth muscle cells via the PI3K/Akt pathway

in Respiratory Pharmacology

Yunbo Tang
Nan Zhou
Xiaohui Ni

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1738301

245 views

Editorial

Published on 11 Feb 2026

Editorial: Targeting adipose tissue for the treatment of metabolic alterations

in Translational Pharmacology

Lorenzo Flori
Bruno Ramos-Molina
Vincenzo Calderone
Alma Martelli

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1797423

259 views

Review

Published on 11 Feb 2026

Research progress on mechanisms and applications of Chinese herbal pairs in treating hyperplasia of mammary gland

in Ethnopharmacology

Lu Liu
Yuxuan Zhang
Wei Shen
Wanyu Li
Xudong Lei
Xiaoyan Dai

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1704606

401 views

Review

Published on 11 Feb 2026

Review of neuroprotective potential of natural products against hypoxia-induced neuronal injury

in Neuropharmacology

Yuman Zhang
Xingyu Yi
Dingzhong Wang
Cunlong Kong
Yan Xu
Jianping Xie

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1746683

230 views

Original Research

Published on 11 Feb 2026

AUM-302, a novel triple PIM/PI3K/mTOR inhibitor, synergizes with RAS inhibition and impedes the growth of pancreatic ductal adenocarcinoma spheroids and organoids

in Pharmacology of Anti-Cancer Drugs

Emma Wen
Catalina Vera
Sahaana Kesavan
Fatim Kouassi
Joseph F. LaComb
Neecki Zand
David A. Tuveson
Amber N. Habowski
Antonio T. Baines
Agnieszka B. Bialkowska

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1685433

398 views

Correction

Published on 11 Feb 2026

Correction: Advances in pharmacokinetic-pharmacodynamic modeling for anesthesia, 1987–2024: a review

in Neuropharmacology

Yara Tulbah
Ibrahim Aljamaan

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1804067

184 views

Original Research

Published on 11 Feb 2026

Miquelianin and spiraeoside from Filipendula ulmaria mitigate α-synuclein accumulation in C.elegans and reduce the expression of neuroinflammatory cytokines in human microglia

in Ethnopharmacology

Martina Redl
Sabrina Weisenburger
Andreas Wasilewicz
Ulrike Grienke
Martin D. Lehner
Dirk Bredenbröker
Judith M. Rollinger

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1720314

362 views

Original Research

Published on 11 Feb 2026

Impaired adenosine pathways in HFpEF: insights into cardiorenal alterations and endothelial responses

in Cardiovascular and Smooth Muscle Pharmacology

Maria Antonietta Riemma
Gennaro Madonna
Elena Mele
Elena Conte
Marialucia Telesca
Giacomo De Palma
Barbara Kutryb-Zając
Carla Cicala
Paola Imbrici
Antonella Liantonio

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1720123

358 views

Original Research

Published on 11 Feb 2026

Multitarget mechanisms of the herb pair Achyranthes bidentata and Paeonia lactiflora Pall. in ameliorating hypertensive cardiomyopathy: combining network pharmacology and functional exploration

in Cardiovascular and Smooth Muscle Pharmacology

Yanyan Zhang
Yingwanqi Wang
Jianing Liu
Yu Zhao
Yuhui He
Peimei Yan
Shan Ren
Ying Lyu
Weiwei Jia
Yuran Sun

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1717533

329 views

Original Research

Published on 11 Feb 2026

A retrospective clinical analysis of inappropriate Xiangdan Injection use: clinical risk profiling and computational hypothesis generation

in Ethnopharmacology

Ji Zeng
Yougang Wei
Jinke Zhang
Yiming Xu

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1742792

404 views

Review

Accepted on 10 Feb 2026

Inconsistent medication recommendations for immune-mediated inflammatory diseases across pregnancy, lactation, and paternal preconception: a guideline-based review

in Obstetric and Pediatric Pharmacology

Elise Van den Broeck
Sien Lenie
Marc Ferrante
Ellen De Langhe
Barbara Neerinckx
Tom Hillary
Kristel Van Calsteren
Anne Smits
Laure Sillis
Mette Julsgaard

Frontiers in Pharmacology

Review

Accepted on 10 Feb 2026

Epidemiological relevant effect biomarkers for thyroid hormone system related adverse outcome pathways: a literature review

in Predictive Toxicology

Maria Wielsøe
Manhai Long
Antonios K. Stratidakis
Elisavet Renieri
Dimosthenis Sarigiannis
Eva Cecilie Bonefeld-Jørgensen

Frontiers in Pharmacology

Original Research

Accepted on 10 Feb 2026

Hydrochlorothiazide and Chlorthalidone Use and Glaucoma Risk: Pharmacovigilance Analysis and Nationwide Cohort Study

in Pharmacoepidemiology

Jooyoung Yoon
Jiyeong Kim
Ko Eun Kim
Jee-Eun Chung
Seong Joon Ahn

Frontiers in Pharmacology

216 views

Original Research

Accepted on 10 Feb 2026

Comprehensive dose-dependent hepatorenal protective effects of Ziziphus nummularia leaf extract against Quinolphos-induced toxicity in Wistar rats

in Ethnopharmacology

Ramya Rengaraj
Stalin Arumugam
Praveen Kumar Dharmaraj
Varadharajan Gokula
Aarthi Murugavel
Mohamed Saiyad Musthafa
Cristiana Roberta Multisanti
Caterina Faggio

Frontiers in Pharmacology

Original Research

Accepted on 10 Feb 2026

Antifungal and anti-virulence activities of cinnamon, thyme, and clove essential oils against Candida species

in Pharmacology of Infectious Diseases

Toni Gabaldón
Islam Ahaik
Juan Carlos Nunez-Rodríguez
Sònia Abelló-Cros
Oscar Yanes
Samira Bouhdid

Frontiers in Pharmacology

106 views

Original Research

Accepted on 10 Feb 2026

Efficacy and safety of camrelizumab-based regimens in advanced squamous cell carcinoma patients: a prospective multicenter study

in Translational Pharmacology

Weijia Jiang
Wanren Peng
Dong Qian
Genhe Wang
Hong Qian
Wenxia Deng
Zishu Wang
Zhiyong Wei
Tai Ma
Dong Zhao

Frontiers in Pharmacology

29,498 articles

articles

From dopamine to muscarine: xanomeline-trospium (KarXT) as a novel direction in the psychopharmacotherapy of schizophrenia

Efficacy and safety of traditional Chinese classic prescriptions combined with metformin in the treatment of type 2 diabetes mellitus: a Bayesian network meta-analysis

Platelet-rich plasma for the treatment of postoperative anastomotic fistula of the gastrointestinal tract: a case report

Plant polysaccharides in neuroprotection: mechanistic insights across central nervous system disorders

Innate immune signalling, neuroinflammation and network plasticity in temporal lobe epilepsy

Yttrium-90 radioembolization as an in vivo immune modulator: clinical evidence and pharmacologic implications

Oleaceae plants: a source of metabolites with atheroprotective potential

Regional absorption of talinolol mediated by intestinal transporters: insights from PBPK modeling analysis

LYVE-1 identifies asthma and drives PDGF-BB-induced proliferation, migration, and oxidative stress in airway smooth muscle cells via the PI3K/Akt pathway

Editorial: Targeting adipose tissue for the treatment of metabolic alterations

Research progress on mechanisms and applications of Chinese herbal pairs in treating hyperplasia of mammary gland

Review of neuroprotective potential of natural products against hypoxia-induced neuronal injury

AUM-302, a novel triple PIM/PI3K/mTOR inhibitor, synergizes with RAS inhibition and impedes the growth of pancreatic ductal adenocarcinoma spheroids and organoids

Correction: Advances in pharmacokinetic-pharmacodynamic modeling for anesthesia, 1987–2024: a review

Miquelianin and spiraeoside from Filipendula ulmaria mitigate α-synuclein accumulation in C.elegans and reduce the expression of neuroinflammatory cytokines in human microglia

Impaired adenosine pathways in HFpEF: insights into cardiorenal alterations and endothelial responses

Multitarget mechanisms of the herb pair Achyranthes bidentata and Paeonia lactiflora Pall. in ameliorating hypertensive cardiomyopathy: combining network pharmacology and functional exploration

A retrospective clinical analysis of inappropriate Xiangdan Injection use: clinical risk profiling and computational hypothesis generation

Inconsistent medication recommendations for immune-mediated inflammatory diseases across pregnancy, lactation, and paternal preconception: a guideline-based review

Epidemiological relevant effect biomarkers for thyroid hormone system related adverse outcome pathways: a literature review

Hydrochlorothiazide and Chlorthalidone Use and Glaucoma Risk: Pharmacovigilance Analysis and Nationwide Cohort Study

Comprehensive dose-dependent hepatorenal protective effects of Ziziphus nummularia leaf extract against Quinolphos-induced toxicity in Wistar rats

Antifungal and anti-virulence activities of cinnamon, thyme, and clove essential oils against Candida species

Efficacy and safety of camrelizumab-based regimens in advanced squamous cell carcinoma patients: a prospective multicenter study