Frontiers in Pharmacology | Ethnopharmacology

Systematic Review

Published on 04 Nov 2025

Comparative efficacy of commercial Chinese polyherbal preparation for coronary microvascular dysfunction: a systematic review and network meta-analysis of randomized controlled trials

in Ethnopharmacology

Wujiao Wang
Jun Zhang
Xinyue Wang
Yuxuan Li
Yudou Li
Fenglan Pu
Zhifei Yang
Jie Wan
Haiyan Zhu
Tianli Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1642864

100 views

Review

Accepted on 03 Nov 2025

Traditional uses, nutritional properties, phytochemical metabolites, pharmacological properties, and potential applications of Lilium spp.: A systematic review

in Ethnopharmacology

Yi Wang
CHEN HUAN
Pucheng Feng
Deyun Wang
Xiaoquan Du

Frontiers in Pharmacology

Original Research

Accepted on 03 Nov 2025

Integrated gut microbiota and metabolomics analysis reveals the antitumor effects of ergosta-4,6,8(14),22-tetraen-3-one purified from the medicinal fungus Pholiota adiposa in tumor-bearing mice

in Ethnopharmacology

Boyuan LIU
Xiao-yan Wang
Yan Liu
Junsen Qin
Shan Zheng
Jiaxin Zhang
Xuemei Hu

Frontiers in Pharmacology

Review

Accepted on 03 Nov 2025

A critical review of natural products driven correction of bile acid dysregulation: a therapeutic strategy for nonalcoholic fatty liver disease

in Ethnopharmacology

Qing Peng
Liyuan Hao
Shenghao Li
Fei Yu
Na Li
Xiaoyu Hu

Frontiers in Pharmacology

118 views

Correction

Accepted on 03 Nov 2025

Zhuriheng pills improve adipose tissue dysfunction and inflammation by modulating PPARγ to stabilize atherosclerotic plaques

in Ethnopharmacology

Qiong Zhai
Fangyuan Liang
Guanlin Yang
Zhimin Liu
Xin Dong
Ren Bu
Peifeng Xue
Shengsang Na
Xuan Zhang
Pengwei Zhao

Frontiers in Pharmacology

Review

Accepted on 03 Nov 2025

The pathogenesis of diabetic kidney disease and the therapeutic potential of bioactive substances

in Ethnopharmacology

Yan Chen
He Li
Qiuju Dai
Zhen Tan
Huihui Wu
Zhiyi Xu
Guangwei Wang
Yang Fang
Jie Luo
Mingliang Huang

Frontiers in Pharmacology

Original Research

Accepted on 03 Nov 2025

Polyphenol-Rich Morus nigra L. Extract Mitigates Neuroinflammation and Cognitive Impairment through Gut–Brain Axis Modulation in an Alzheimer's Disease Rat Model

in Ethnopharmacology

Yue Li
Yangyi Zhang
Mengwen Liu
Tuerxunayi· Dawuti
Chen Xuanshi
Hui Xiao

Frontiers in Pharmacology

Original Research

Published on 03 Nov 2025

Multi-omics analysis elucidates the therapeutic mechanisms of the Quzhi formula in metabolic dysfunction-associated steatohepatitis targeting gut microbiota, lipid metabolism, and the role of its metabolite fraxin

in Ethnopharmacology

Jiao-Xiang Wu
Yue-Lan Wu
Mei-Fang Li
Nian Liu
Ying Liu
Yan-Ping Huang
Yuan Gan
Xiao-Yu Wang
Hai-Sheng Chai
Jin Xu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1694242

156 views

Review

Published on 03 Nov 2025

Integrated toxicology of Aconitum carmichaelii Debx.: bridging traditional toxicity-efficacy understanding and modern toxicology

in Ethnopharmacology

Xin-Yu Li
Li Zhou
Zhen-Hong Jiang
Yong Liang
Ya-Guo Fan
Zhao-Hui Ding
Hao Chen
Wen-Jun Liu
Xiang Zhou
Huan-Hua Xu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1667059

244 views

Original Research

Published on 03 Nov 2025

Crosstalk between MSC-extracellular vesicles and Olea europaea leaf extract in encapsulated liposomal hydrogel: attenuation of neuroinflammation and brain neurotransmitter and memory impairment associated with obesity-induced high-fat diet

in Ethnopharmacology

Doaa Ibrahim
Ioan Pet
Hoda S. Sherkawy
Haitham Eldoumani
Ola M. Fathy
Aya Elgamal
Heba S. A. Gharib
Asmaa A. Muhammed
Aya Sh. Metwally
Mirela Ahmadi

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1621092

393 views

Original Research

Published on 03 Nov 2025

The potential value of the use of berberine in depression: a systematic review and meta-analysis of preclinical studies

in Ethnopharmacology

Bifang Yao
Zhengxiang Long
Xiaojiao Lin
Guangqiang Chen
Xiaoyu Li
Ziqi Ye
Jiahong Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1664784

278 views

Review

Accepted on 31 Oct 2025

Integrating clinical evidence with natural product therapies for elderly-onset type 2 diabetes

in Ethnopharmacology

Yoon Sin Oh
Chae-Eun Kim
Kyong Kim
Eun-Young Park

Frontiers in Pharmacology

200 views

Review

Accepted on 31 Oct 2025

Harnessing the Multi-Targeted Potential of Rehmanniae Radix Natural productsBioactives Against Renal Fibrosis: A Mechanistic Review

in Ethnopharmacology

Keqin Zhao
Han Zhu
Liping Zheng
Wenru Wang
Peng Liu
Ren-Huan Yu
Xiaobei Ma

Frontiers in Pharmacology

231 views

Original Research

Accepted on 31 Oct 2025

Six-Methoxyflavone Suppresses CircPIAS1 Biogenesis via Targeting PTBP1 and, in Combination with IFN-γ, Promotes Ferroptosis in Melanoma

in Ethnopharmacology

Yong-Qi Guo
Xi Wu
Xin Zang
Cheng-Yan Liu
Meng-Yue Wang
Cheng-Mei Xiao
Hui Hou
Li-Fang Zhang
Yuan-Zheng Xia
Lingyi Kong

Frontiers in Pharmacology

180 views

Original Research

Accepted on 31 Oct 2025

Anti-inflammatory effect of a pimarane diterpenoid isolated from Nepeta adenophyta Hedge. based on network Analysis approach and experimental assessment

in Ethnopharmacology

Wei Zhao
Meng Li
Qing Chuan Jia
Iftikhar Ali
Long Chen

Frontiers in Pharmacology

166 views

Systematic Review

Accepted on 31 Oct 2025

Preclinical Evidence and Mechanistic Insights of Ligustilide in Ischemic Stroke: A Systematic Review and Meta-Analysis

in Ethnopharmacology

Hengtong An
Shuhan Guo
Wei Wang
Tiangang Zheng
Xiaofei Jin
Xiaohong Zhou
Weijuan Gao

Frontiers in Pharmacology

131 views