Frontiers in Pharmacology | Ethnopharmacology

Original Research

Published on 01 May 2025

Bioactive lipids and allelopathic potential of the invasive plant Heracleum sosnowskyi: insights into its fatty acid composition, antimicrobial and cytotoxic effects

in Ethnopharmacology

Eva Borska
Jorens Kviesis
Anna Ramata-Stunda
Vizma Nikolajeva
Linda Ansone-Bertina
Martins Boroduskis
Maris Klavins

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1582694

677 views

Original Research

Published on 01 May 2025

Efficacy of sodium new houttuyfonate against Aspergillus flavus: insights from in vitro and in vivo models of invasive pulmonary aspergillosis

in Ethnopharmacology

Yilin Bao
Dingxian Feng
Jinping Zhang
Xiaoyan Hu
Xinyou Yang
Yingyu Mao
Zhangyong Song

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1577561

609 views
1 citation

Original Research

Published on 30 Apr 2025

Beta-boswellic acid facilitates diabetic wound healing by targeting STAT3 and inhibiting ferroptosis in fibroblasts

in Ethnopharmacology

Ziyang Han
Weiping Wu
Zeming Bai
Yiping Xiu
Dapeng Zhou

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1578625

1,102 views

Correction

Published on 30 Apr 2025

Corrigendum: Platycodon grandifloras polysaccharides deeply participate in the anti-chronic bronchitis effects of platycodon grandiflorus decoction, a representative of “the lung and intestine are related”

in Ethnopharmacology

Yang Liu
Qingqing Chen
Rongrong Ren
Qingqing Zhang
Guiming Yan
Dengke Yin
Mingyan Zhang
Ye Yang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1566123

484 views

Original Research

Published on 30 Apr 2025

Chemopreventive and therapeutic effects of Hippophae rhamnoides L. fruit peels evaluated in preclinical models of breast carcinoma

in Ethnopharmacology

Dana Dvorska
Dominika Sebova
Karol Kajo
Andrea Kapinova
Emil Svajdlenka
Michal Goga
Richard Frenak
Jakub Treml
Sandra Mersakova
Jan Strnadel

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1561436

1,664 views

Original Research

Published on 30 Apr 2025

Resveratrol attenuates the priapism phenotype in sickle cell mice by restoring NO-cGMP-PDE5 signaling and reducing NADPH oxidase 2 expression

in Ethnopharmacology

Carolina Oliveira Splendore
Tammyris Helena Rebecchi Silveira
Dalila Andrade Pereira
Beatriz Pereira Bossarino
Mariana Gonçalves de Oliveira
Fabiano Beraldi Calmasini
Arthur L. Burnett
Fernando Ferreira Costa
Fábio Henrique Silva

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1551533

842 views

Original Research

Published on 30 Apr 2025

Regulating mitochondrial oxidative phosphorylation and MAPK signaling: wedelolactone as a novel therapeutic for radiation-induced thrombocytopenia

in Ethnopharmacology

Zhichao Li
Qinyao Li
Shuang Wu
Xinyue Mei
Xiao Qi
Sheng Liu
Gan Qiao
Hongping Shen
Jiesi Luo
Jing Zeng

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1508215

1,062 views

Original Research

Published on 30 Apr 2025

Menthacarin, a proprietary combination of peppermint and caraway oil, alters cultured human fecal microbiota composition, resulting in increased SCFA production

in Ethnopharmacology

Martin D. Lehner
Philippe Ulsemer
Sandra Christochowitz

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1569052

1,742 views

Original Research

Published on 29 Apr 2025

Ophiopogonin D improves pancreatic islet cell dedifferentiation to treat diabetes by regulating the GRP78/ROS/PDX1 signaling pathway

in Ethnopharmacology

Haoxiang Sun
Ruixiang Tan
Yongzhi Sun
Yimeng Li
Ying Xie
Cheng Zhang
Jianping Song
Wei Zhu
Jiuyao Zhou
Changsheng Deng

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1563201

964 views

Original Research

Published on 29 Apr 2025

Triptolide alleviates psoriasis through inhibiting the Wnt5a/β-Catenin signaling pathway

in Ethnopharmacology

Eryang Chen
Lei Wang
Qu Wang
Yan Cai
Yaning Dou
Hongyan Qu
Junyi Zhu
Haiyang Zhao
Suqing Zheng
Chengguang Zhao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1534118

970 views

Original Research

Published on 29 Apr 2025

Ethyl acetate extract of Ruta graveolens: a specific and potent inhibitor against the drug-resistant EGFR_T790M mutant in NSCLC

in Ethnopharmacology

Vikas Kumar
Leena Chauhan
Deepa Singh
Akash Kumar
Rajkumar Kulandaisamy
Tushar Kushwaha
Kamal Baswal
Rajan Singh
Saroj Kumar
Shivajirao L. Gholap

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1570108

1,252 views
1 citation

Original Research

Published on 29 Apr 2025

Integrative in silico and in vitro analysis of Pinus roxburghii essential oil: unveiling its antioxidant, antidiabetic, and antiglycation potential

in Ethnopharmacology

Rubina Naz Qaisrani
Shah Iram Niaz
Raheela Bano
Hatem A. Abuelizz
Arooj Mohsin Alvi
Sadia Chaman
Qaiser Aziz
Muhammad Asif Wazir
Muhammad Akram
Saiqa Ishtiaq

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1554562

802 views

Clinical Trial

Published on 28 Apr 2025

Efficacy and safety of traditional Chinese medicine Elian Granule for chronic atrophic gastritis: a multi-center, randomized, double-blind, placebo-controlled study

in Ethnopharmacology

Qingling Jia
Yuebo Jia
Yongqi Chen
Likun Guo
Chenheng Wu
Jun Cong
Zhijian Gu
Xuejun Li
Shengquan Fang
Zhuhua Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1545313

971 views

Original Research

Published on 28 Apr 2025

Exploring the therapeutic potential and in vitro validation of baicalin for the treatment of triple-negative breast cancer

in Ethnopharmacology

Yuan Ma
Ying Pan
Qiancheng Zhao
Chongheng Zhang
Haitao He
Lihua Pan
Jianling Jia
Aiping Shi
Yiming Yang
Wenfeng Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1530056

993 views

Original Research

Published on 28 Apr 2025

Sigesbeckia pubescens makino alleviates ulcerative colitis in mice by modulating the Nrf2/Keap1 pathway

in Ethnopharmacology

Qiu-Shuo Ma
Qi-Ling Chen
Guo-Ping Wu
Ya-Wen Yao
Yu-Xin Fan
Ke-Gang Linghu
Jun-Ming Chen
Wei Xiong
Hua Yu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1588525

962 views

Original Research

Published on 28 Apr 2025

Cassiae semen extract ameliorates hyperlipidemia in rats by modulating lipid metabolism and FcγR-mediated immune regulation

in Ethnopharmacology

Mingyue Lv
Yannan Zheng
Man Yuan
Errui Zhang
Min Zheng
Guangyao Liu
Min Zheng
Weiliang Gu
Hongxi Xu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1546119

762 views