Frontiers in Pharmacology | Ethnopharmacology

Original Research

Published on 25 Jul 2025

Comparative effects of raw and processed cistanche glycosides on the HPT axis and gut microbiota in a rat model of kidney-yang deficiency

in Ethnopharmacology

Xiaoqing Shen
Jing Lian
Chao Zhang
Yixiang Miu
Yuan Zhang
Ji Shi
Nan Xu
Tianzhu Jia

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1597564

254 views

Review

Published on 25 Jul 2025

Natural products for intervertebral disc degeneration: mechanistic insights and therapeutic potentials

in Ethnopharmacology

Zenghan Wu
Jiang Chen
Wenhai Luo
Tao Kuang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1605764

Original Research

Published on 25 Jul 2025

A glycogen derived from sea urchin-Strongylocentyotus internedius shifts macrophages to the M1 phenotype and enhances the anti-pancreatic cancer activity of gemcitabine

in Ethnopharmacology

Zhenzhen Deng
Haoyu Yu
Ning Wu
Qingchi Wang
Jing Wang
Yang Yue
Lihua Geng
Quanbin Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1600349

107 views

Original Research

Published on 25 Jul 2025

Schisandrin B alleviates metabolic associated fatty liver disease by regulating the PPARγ signaling pathway and gut microbiota in mice

in Ethnopharmacology

Jiuchen Wan
Chenjian Lang
Meng Gao
Feilong Liu
Xiyuan Feng
He Li
Chunmei Wang
Jinghui Sun

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1583307

Clinical Trial

Published on 25 Jul 2025

Effects of the efficacy of the Yi Shen Tiao Gan formula on aromatase inhibitor associated musculoskeletal syndrome: a randomized controlled trial

in Ethnopharmacology

Yan Zhang
Meiling Chu
Meina Ye
Yiqin Cheng
Hui Cong
Yulian Yin
Hongfeng Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1639714

515 views

Original Research

Published on 25 Jul 2025

Assessing the adherence of large language models to clinical practice guidelines in Chinese medicine: a content analysis

in Ethnopharmacology

Weilong Zhao
Honghao Lai
Bei Pan
Jiajie Huang
Danni Xia
Chunyang Bai
Jiayi Liu
Jianing Liu
Yinghui Jin
Hongcai Shang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1649041

152 views

Review

Published on 25 Jul 2025

From traditional remedy to modern therapy: a comprehensive review of palmatine’s multi-target mechanisms and ethnopharmacological potential

in Ethnopharmacology

Zhoujing Shi
Lutuo Han
Huasen Yang
Geling Lu
Zhouying Shi
Boyan Ma

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1624353

217 views

Original Research

Accepted on 24 Jul 2025

Total Ginsenoside Induces Fetal Hemoglobin in β-Thalassemia: Evidence from In Vitro and In Vivo of Mice Model

in Ethnopharmacology

Dongling Cai
Ying Chan
Guangyu He
Yamin Kong
Aiqi Cai
Yan Guo
Baosheng Zhu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1578237

Original Research

Accepted on 24 Jul 2025

Ultrasound-Assisted Extraction of Peucedanum ostruthium Leaves: A Feasible Alternative to Rhizomes for Industrial Applications

in Ethnopharmacology

Chih-Yu Chen
Guey-Horng Wang
Jong-Tar Kuo
Yueh-Te Lin
Hsiu-Ju Huang
Yu-Chi Chang
Ying-Chien Chung

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1636312

Review

Published on 24 Jul 2025

Effects and molecular mechanisms of Achyranthes bidentata Blume and Cyathula officinalis K.C. Kuan in the treatment of rheumatoid arthritis

in Ethnopharmacology

Liu-Bo Zhang
Yu Yan
Wen-Wen Lian
Wei Zhou
Cong-Yuan Xia
Jun He
Yuan Xu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1619776

214 views

Review

Published on 24 Jul 2025

Recent advances in polysaccharides derived from the Dendrobium nobile Lindl.: preparation strategies, structural characteristics, biological activity, and structure-activity relationships

in Ethnopharmacology

Xiao Zhou
Haizheng Bi
Zhaojiong Zhang
Xingyu Wang
Mengru Zhang
Meng Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1631637

243 views

Review

Published on 24 Jul 2025

The role of trimethylamine N-oxide in disease pathogenesis and the therapeutic potential of traditional Chinese medicine

in Ethnopharmacology

Zizhen Qin
Wanning Wu
Xinyu Yang
Xiao Wang
Anni Ding
Yueyi Huang
Jiaxuan Tang
Siyuan Jiang
Peng Zhang
Chenwei Qian

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1592524

195 views

Original Research

Published on 24 Jul 2025

Hybrid Cannabis sativa L. inflorescences exert an anti-inflammatory effect through the modulation of MAPK/NF-κB/NLRP3 inflammasome and JAK1/STAT6 pathway in HaCaT cells

in Ethnopharmacology

Ji-Ye Han
Do-Won Lim
Osoung Kwon
Yun Jung Lee
Hye Yung Choi
Hyun-Ju Jung
Soohyang Noh
Mansoo Cho
Sung Suk Kang
Young-Mi Lee

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1617180

283 views

Original Research

Published on 24 Jul 2025

The active metabolites of Eucommia ulmoides leaves alleviate atherosclerosis induced by a high-fat diet and VD3 in rats

in Ethnopharmacology

Man Gong
Lili Zhu
Bingdi Cui
Cong Ling
Xiaoqian Liu
Zhimin Wang
Liping Dai

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1625200

375 views

Original Research

Accepted on 23 Jul 2025

Menthol-Thymol NADES as a fungicidal and chemosensitizing agent against multidrug-resistant Candida albicans: ROS induction, efflux pump inhibition, and synergy with fluconazole

in Ethnopharmacology

Melisa Negro
Pamela Soledad Bustos
Lautaro Bellezze
Maria Gabriela Ortega
Javier Echeverria
María Fernanda Silva
MARIANA ANDREA PERALTA

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1643472

Original Research

Accepted on 23 Jul 2025

Attitudes and Use of Complementary and Alternative Medicine: A Cross-Sectional Comparison Between Medical and Non-Medical Students

in Ethnopharmacology

Mohammad Ali Zakeri
Mahlagha Dehghan
Yasser Soltanmoradi
Maryam Zakeri
Shiva Monfared
Gulsah Kose
Hojjat Farahmandnia
Alaa Hamza Hermis
Xiao Xu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1529079