Frontiers in Pharmacology | Experimental Pharmacology and Drug Discovery

Correction

Published on 07 Mar 2025

Corrigendum: Novel chemical scaffolds to inhibit the neutral amino acid transporter B0AT1 (SLC6A19), a potential target to treat metabolic diseases

in Experimental Pharmacology and Drug Discovery

Aditya Yadav
Nishank Shah
Praveen Kumar Tiwari
Kiran Javed
Qi Cheng
Indrapal Singh Aidhen
Stefan Bröer

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1485054

980 views

Original Research

Published on 07 Mar 2025

Pharmacophore screening, molecular docking, and MD simulations for identification of VEGFR-2 and c-Met potential dual inhibitors

in Experimental Pharmacology and Drug Discovery

Junmin Dong
Xiaohua Hao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1534707

1,487 views

Mini Review

Published on 07 Mar 2025

Therapeutic modulation of protein RBM3 for ischemic stroke treatment

in Experimental Pharmacology and Drug Discovery

Paulo Ávila-Gómez
Alba Vieites-Prado
Clara Correa-Paz
Lucía Del Pozo-Filíu
Nuria Palomar-Alonso
Francisco Campos
Esteban López-Arias

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1555115

1,031 views

Editorial

Published on 06 Mar 2025

Editorial: Cellular and molecular mechanisms in metabolic disorders: role of inflammation and oxidative stress

in Experimental Pharmacology and Drug Discovery

Munkhtuya Tumurkhuu
Shahnawaz Ali Bhat
Md Zakir Hossain
Mohammad Shafiq
Md Saquib Hasnain
Amit Kumar Nayak
Syed Anees Ahmed

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1580553

1,026 views
1 citation

Original Research

Published on 06 Mar 2025

Adverse event profile of lomustine and temozolomide: a descriptive analysis from WHO-VigiAccess

in Experimental Pharmacology and Drug Discovery

Hua Luo
Shaohua Fan
Lu Liang
Youfu He
Jiangjie Chen
Chenghao Xu
Jing Zhu
Liwei Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1534802

942 views

Original Research

Published on 06 Mar 2025

Ursodeoxycholic and chenodeoxycholic bile acids alleviate endotoxininduced acute lung injury in rats by modulating aquaporin expression and pathways associated with apoptosis and inflammation

in Experimental Pharmacology and Drug Discovery

Tatjana Milivojac
Milkica Grabež
Ljiljana Amidžić
Alma Prtina
Aleksandra Krivokuća
Ugljesa Malicevic
Maja Barudžija
Milka Matičić
Snežana Uletilović
Nebojša Mandić-Kovačević

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1484292

1,075 views
1 citation

Review

Published on 05 Mar 2025

Advanced materials for cancer treatment and beyond

in Experimental Pharmacology and Drug Discovery

Lei Zhang
Yanan Wang
Yangjia Li
Zhe-Sheng Chen
Chaohua Hu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1557155

1,160 views

Original Research

Published on 05 Mar 2025

Obesity promotes immunotherapy efficacy by up-regulating the glycolytic-mediated histone lactacylation modification of CD8+ T cells

in Experimental Pharmacology and Drug Discovery

Kai-Xuan Wang
Dong-Min Shi
Xiao-Li Shi
Jing-Yuan Wang
Xing-Hao Ai

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1533464

2,334 views

Original Research

Published on 05 Mar 2025

Efficient substructure feature encoding based on graph neural network blocks for drug-target interaction prediction

in Experimental Pharmacology and Drug Discovery

Guojian Deng
Changsheng Shi
Ruiquan Ge
Riqian Hu
Changmiao Wang
Feiwei Qin
Cheng Pan
Haixia Mao
Qing Yang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1553743

1,010 views

Original Research

Published on 05 Mar 2025

Novel selective glucocorticoid receptor modulator GRM-01 demonstrates dissociation of anti-inflammatory effects from adverse effects on glucose and bone metabolism

in Experimental Pharmacology and Drug Discovery

Florian Jakob
Stephanie Hennen
Michael Gautrois
Feras Khalil
Andrew Lockhart

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1542351

2,313 views

Review

Published on 04 Mar 2025

Recent advances in the multifaceted mechanisms of catalpol in treating osteoporosis

in Experimental Pharmacology and Drug Discovery

Na Li
Xiaoying Mu
Shudong Zhang
Huaxin Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1560715

1,093 views

Original Research

Accepted on 28 Feb 2025

Innovative application of mefloquine and methacycline in combating Tet(X3/X4)-positive Escherichia coli infections

in Experimental Pharmacology and Drug Discovery

Yonglin Zhou
Qianyu Zhou
Jinjing Xue

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1542729

136 views

Original Research

Published on 28 Feb 2025

Exogenous Galectin-9 prevents peri-implantitis in rats by regulating macrophage polarization

in Experimental Pharmacology and Drug Discovery

Lujin Cheng
Xiaowei Ji
Huerxidai Yilihamujiang
Shuya Dong
Long Mei
Guo Lin
Qihan Tang
Zhongcheng Gong

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1533468

1,062 views

Review

Published on 28 Feb 2025

Neuropeptides as regulators of bone metabolism: from molecular mechanisms to traditional Chinese medicine intervention strategies

in Experimental Pharmacology and Drug Discovery

Qing Lin
Biyi Zhao
Jiajia Huang
Rumeng Chen
Weipeng Sun
Qianyun Ye
Li Yang
Xiaofeng Zhu
Xiaoyun Li
Ronghua Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1516038

1,210 views

Review

Published on 27 Feb 2025

Trends in the research and development of peptide drug conjugates: artificial intelligence aided design

in Experimental Pharmacology and Drug Discovery

Dong-E Zhang
Tong He
Tianyi Shi
Kun Huang
Anlin Peng

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1553853

2,911 views

Original Research

Published on 27 Feb 2025

Discovery of highly potent and novel LSD1 inhibitors for the treatment of acute myeloid leukemia: structure-based virtual screening, molecular dynamics simulation, and biological evaluation

in Experimental Pharmacology and Drug Discovery

Ye Hong
Yuting Wang
Ziyi Hao
Xingxia Zhang
Yejun Si
Guoqiang Lin
Shurong Zhang
Miao-Miao Niu
Xiaotian Yang
Yanming Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1510319

1,246 views