Frontiers in Pharmacology | Pharmacogenetics and Pharmacogenomics

Original Research

Published on 24 Oct 2024

Impact of single-nucleotide variants and individual characteristics on adverse events of L-asparaginase in children with acute lymphoblastic leukemia

in Pharmacogenetics and Pharmacogenomics

Jesús Alonso Gándara-Mireles
Ismael Lares-Asseff
Elio Aarón Reyes Espinoza
Verónica Loera Castañeda
Lourdes Patricia Córdova Hurtado
Flor de María Reyes Gutiérrez
Antonio Sandoval-Cabrera
Ignacio Villanueva Fierro
Julio Cesar Grijalva Ávila
Claudia Castro Arreola

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1423049

1,167 views
1 citation

Case Report

Published on 23 Oct 2024

Case report: Acute liver failure during deferasirox therapy and the potential role of pharmacogenetics

in Pharmacogenetics and Pharmacogenomics

Belén García-Fariña
Lydia Rink
Virginia Santarini
Marco Westkemper
Christian Dohna-Schwake
Birte Möhlendick

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1477755

1,967 views
1 citation

Original Research

Published on 18 Oct 2024

The role of NOP58 in prostate cancer progression through SUMOylation regulation and drug response

in Pharmacogenetics and Pharmacogenomics

Wei Guo
Shi Zong
Tao Liu
Yi Chao
Kaichen Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1476025

2,313 views
2 citations

Original Research

Published on 17 Oct 2024

Evaluation of the role of metabolizing enzymes and transporter variants in ezetimibe pharmacokinetics

in Pharmacogenetics and Pharmacogenomics

Eva González-Iglesias
Dolores Ochoa
Marcos Navares-Gómez
Pablo Zubiaur
Marina Aldama
Tamara de la Torre
Marta de los Ríos-Rodríguez
Paula Soria-Chacartegui
Andrea Rodríguez-Lopez
Francisco Abad-Santos

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1414059

1,324 views
1 citation

Original Research

Published on 11 Oct 2024

HLA-B allele frequencies and implications for pharmacogenetics in the Kuwaiti population

in Pharmacogenetics and Pharmacogenomics

Mohammed Dashti
Md Zubbair Malik
Abdullah Al-Matrouk
Saeeda Bhatti
Rasheeba Nizam
Sindhu Jacob
Fahd Al-Mulla
Thangavel Alphonse Thanaraj

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1423636

1,592 views

Original Research

Published on 09 Oct 2024

Pharmacogenetics testing for poor response to antidepressants: a transnosographic case series

in Pharmacogenetics and Pharmacogenomics

Marie-Agnès Lorvellec
Gilles Sipahimalani
Bertrand Lahutte
Hervé Delacour
Antoine Baldacci
Emeric Saguin

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1440523

2,394 views
1 citation

Case Report

Published on 08 Oct 2024

Pharmacogenomics assists in controlling blood pressure in cardiovascular and cerebrovascular patients during Rehabilitation: a case report

in Pharmacogenetics and Pharmacogenomics

Tian Hou
Luhai Yu
Xiaoliang Shi
Yueran Zhen
Longyu Ji
Zhenbang Wei
Yipeng Xu

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1424683

2,190 views
2 citations

Original Research

Published on 04 Oct 2024

Targeting exercise-related genes and placental growth factor for therapeutic development in head and neck squamous cell carcinoma

in Pharmacogenetics and Pharmacogenomics

Qingyuan Shi
Haiyue Ying
Weibin Weng

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1476076

1,952 views
1 citation

Original Research

Published on 30 Sep 2024

SNPs in cytochromes P450 catalyzing cholesterol degradation in brain are associated with Parkinson’s disease

in Pharmacogenetics and Pharmacogenomics

Polina Petkova-Kirova
Anastasia Kolchina
Stephan Baas
Gudrun Wagenpfeil
Marcus Michael Unger
Julia Maria Schulze-Hentrich
Rita Bernhardt

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1477009

2,030 views

Original Research

Published on 30 Sep 2024

Longitudinal assessment of SNPs rs72552763 and rs622342 in SLC22A1 over HbA1c control among Mexican-Mestizo diabetic type 2 patients

in Pharmacogenetics and Pharmacogenomics

Adiel Ortega-Ayala
Fernando De Andrés
Adrián Llerena
Carlos Miguel Bartolo-Montiel
Gustavo Acosta-Altamirano
Juan Arcadio Molina-Guarneros

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1433519

2,041 views
1 citation

Original Research

Published on 27 Sep 2024

Prevalence of single-nucleotide variants in twenty-five pharmacogenes from a Cuban sample cohort

in Pharmacogenetics and Pharmacogenomics

Elizabeth Reyes-Reyes
José Alfredo Herrera-Isidrón
Elizabeth Cuétara-Lugo
Zhiv Shkedy
Dirk Valkenborg
Claudina Angela Pérez-Novo
Gisselle Fernández-Peña
Idania González-Pérez
Miguel David Fernández-Pérez
Wim Vanden-Berghe

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1467036

1,630 views
1 citation

Original Research

Published on 24 Sep 2024

Advancing pharmacogenomic research in US Hmong populations: prevalence of key single nucleotide variations in California Hmong

in Pharmacogenetics and Pharmacogenomics

Boguang Sun
Tou Thao
Kathleen Culhane-Pera
Eric Yang
Mai Yang Thor
Pao Yang
Metta Xiong
Zoua Vang
Robert J. Straka

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1432906

934 views

Case Report

Published on 23 Sep 2024

Case report: A case of severe capecitabine toxicity due to confirmed in trans compound heterozygosity of a common and rare DPYD variant

in Pharmacogenetics and Pharmacogenomics

Amy de Haar-Holleman
Pieter-Jan Cortoos
Jelle Vlaeminck
Paulien Van Landuyt
Stephane Steurbaut
Freya Vaeyens
Vincent Haufroid

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1459565

1,774 views
1 citation

Original Research

Published on 13 Sep 2024

An exploratory analysis of associations of genetic variation with the efficacy of tocilizumab in severe COVID-19 patients. A pharmacogenetic study based on next-generation sequencing

in Pharmacogenetics and Pharmacogenomics

Alejandro Durán-Sotuela
Jorge Vázquez-García
Sara Relaño-Fernández
Vanesa Balboa-Barreiro
Juan Fernández-Tajes
Francisco J. Blanco
Ignacio Rego-Pérez

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1426826

1,117 views

Original Research

Published on 04 Sep 2024

Association of SLCO1B1 gene variants with angiotensin-converting enzyme inhibitor-induced cough in a Pakistani hypertensive cohort

in Pharmacogenetics and Pharmacogenomics

Arooj Fatima Sheikh
Nayla Munawar
Rukhsana Nawaz
Hizbullah Khan
Mehwish Rafique
Faryal Jahan
Sagheer Ahmed

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1441251

1,340 views

Original Research

Published on 23 Aug 2024

Transcriptome analysis to explore the mechanism of downregulated TNIK influencing the effect of risperidone

in Pharmacogenetics and Pharmacogenomics

Ruixue Yuan
Yaojing Li
Xiangyi Li
Yingmei Fu
Ailing Ning
Dongxiang Wang
Ran Zhang
Shunying Yu
Qingqing Xu

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1431923

1,881 views