Frontiers in Pharmacology | Translational Pharmacology

Original Research

Accepted on 23 Jun 2025

Healthy Participant Engagement in Early Clinical Trials: Results from the European EUFEMED Survey

in Translational Pharmacology

Jelle Klein
Thijs van Iersel
Dick De Vries
Ingrid Klingmann

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1540948

127 views

Review

Published on 20 Jun 2025

Research progress on endoplasmic reticulum homeostasis in acute kidney injury

in Translational Pharmacology

Liling Hu
Huike Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1595845

714 views

Original Research

Published on 19 Jun 2025

Unveiling therapeutic targets and preventive components for kidney insufficiency and blood stasis-type BPH: bridging metabolomics, network pharmacology and reverse screening

in Translational Pharmacology

Xiangpeng Kong
Haiqin Ren
Ke Pei
Yajun Yao
Zhigang Liang
Yunfeng Xue
Shuang Liang
Tongtong Li
Jing Zhang
Yuxia Guo

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1584766

964 views

Review

Published on 18 Jun 2025

Stem cells in the treatment of myocardial injury-induced cardiomyopathy: mechanisms and efficient utilization strategies

in Translational Pharmacology

Jiali Yang
Tian Yue
Jian He
Shiqiang Xiong
Yan Luo
Jun Hou

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1600604

832 views

Review

Published on 13 Jun 2025

Advances and challenges in cancer immunotherapy: mechanisms, clinical applications, and future directions

in Translational Pharmacology

Neeharika Vatsavai
Sumeet Kaur Bhinder
Rahaman Shaik
Shaheen Mahira
Shruti Kapoor
Md Shadab Ali
Deepak Verma
Jay Singh
Sreelakshmi Badavenkatappa Gari
Prabhat Upadhyay

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1602529

1,671 views

Case Report

Published on 12 Jun 2025

Unexpected voriconazole toxicity due to nirmatrelvir/ritonavir: a case report on drug-drug interaction and the role of therapeutic drug monitoring

in Translational Pharmacology

J. López-Hernández
A. B. Guisado-Gil
M. Mejías-Trueba
L. Herrera-Hidalgo
F. J. Reina-Martínez
M. V. Gil-Navarro

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1616061

930 views

Original Research

Published on 02 Jun 2025

Improving drug-drug interaction prediction via in-context learning and judging with large language models

in Translational Pharmacology

He Qi
Xiaoqiang Li
Chengcheng Zhang
Tianyi Zhao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1589788

1,427 views

Original Research

Published on 30 May 2025

Harnessing dual variational autoencoders to decode microbe roles in diseases for traditional medicine discovery

in Translational Pharmacology

Qing Ye
Yaxin Sun

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1578140

495 views

Original Research

Published on 30 May 2025

Functionalized turmeric nanovesicles for precision delivery of doxorubicin in colorectal carcinoma treatment

in Translational Pharmacology

Chen Meng
Xue Yi
Meitao Duan
Ahmed Mahal
Zhiqiang Zhang
Jungang Ren
Ming Chen
Lin Yang
Moxun Xu
Ahmad J. Obaidullah

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1587560

920 views

Original Research

Published on 30 May 2025

Zabedosertib, a novel interleukin-1 receptor-associated kinase-4 inhibitor, shows a favorable pharmacokinetic and safety profile across multiple phase 1 studies

in Translational Pharmacology

Maximilian Feldmüller
Stefan J. Jodl
Bart Ploeger
Andrea Wagenfeld
Herbert Wiesinger
Frank S. Zollmann
Stefan Klein
Ruiping Zhang
Beate Rohde
Joachim Höchel

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1521505

1,308 views

Mini Review

Published on 30 May 2025

GLP-1R in diabetes mellitus: from basic discovery to therapeutics development

in Translational Pharmacology

Shujun Li
Nanqu Huang
Mei Wang
Wendi Huang
Yong Luo
Juan Huang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1610512

1,801 views

Original Research

Published on 22 May 2025

Glucagon-like peptide-1, fibroblast growth factor 21, and other endocrine responses to alcohol ingestion in women before and after metabolic surgery

in Translational Pharmacology

Mariel Molina-Castro
Blair Rowitz
Marta Yanina Pepino

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1575156

1,589 views

Review

Published on 21 May 2025

Advances in biomaterials for osteonecrosis treatment

in Translational Pharmacology

Dapeng Wang
Jiannan Li
Yu Liu
Shuaishuai Wang
Shuo Duan
Zhiyang Liu
Shuaiwei Li
Jun Liang
Guangwei Meng
Minglei Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1559810

1,101 views

Original Research

Published on 14 May 2025

A novel adenosine-to-inosine RNA editing-based nomogram for predicting prognosis of hepatocellular carcinoma

in Translational Pharmacology

Shiqiong Huang
Ji Sun

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1547320

876 views

Review

Published on 14 May 2025

BCAA metabolism in cancer progression and therapy resistance: The balance between fuel and cell signaling

in Translational Pharmacology

Yi Zhou
Jiahui Kou
Wenjin Li
Yuyao Wang
Xingxing Su
Hongguang Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1595176

2,023 views

Mini Review

Published on 13 May 2025

Metabolite 2-aminoadipic acid: implications for metabolic disorders and therapeutic opportunities

in Translational Pharmacology

Weiyan Shi
Zhiqiang Yang
Pengbin Fu
Yang Yang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1569020

1,660 views