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SYSTEMATIC REVIEW article

Front. Public Health

Sec. Infectious Diseases: Epidemiology and Prevention

Volume 13 - 2025 | doi: 10.3389/fpubh.2025.1478001

Prevalence and Associated Factors of Active Trachoma among Children of 1 to 9 Years in Low-income Countries of Africa: A Systematic Review and Meta-analysis

Provisionally accepted
  • 1Department of Environmental Health, College of Medicine and Health Science, Wollo University, Dessie, Ethiopia
  • 2Department of Nursing and Midwifery, Dessie Health Science College, Dessie, Ethiopia

The final, formatted version of the article will be published soon.

Background: Active trachoma is a form of infectious eye disease caused by Chlamydia trachomatis. An estimated 84 million individuals worldwide, primarily children, are affected by active trachoma. Therefore, this systematic review and meta-analysis aimed to determine the pooled prevalence and predictors of active trachoma among children aged 1 to 9 years in lowincome countries of Africa.Methods: Relevant literature was searched from electronic databases. The data was extracted using an Excel sheet and exported to STATA version 17 software. The levels of heterogeneity among studies were assessed using I 2 and p-values. The findings were presented using a table, graph, and forest plot with a 95% confidence interval. A p-value of less than 0.05 was considered statistically significant.

Keywords: Active trachoma, Africa, low-income, Children 1 to 9 years, Surgery, antibiotics, Facial, and Environmental Cleaning

Received: 08 Aug 2024; Accepted: 14 Jul 2025.

Copyright: © 2025 Berhanu, Berihun, Desye, Geto and Daba. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Leykun Berhanu, Department of Environmental Health, College of Medicine and Health Science, Wollo University, Dessie, Ethiopia

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