ORIGINAL RESEARCH article
Front. Public Health
Sec. Public Health Education and Promotion
Volume 13 - 2025 | doi: 10.3389/fpubh.2025.1516413
KNOWLEDGE, PERCEPTION, AND ATTITUDE TOWARDS COVID-19 VACCINES IN THE HO TOWNSHIP, VOLTA REGION
Provisionally accepted
Vivian Tackie1
CHRISTIANA ASIEDU2*Ewoenam Darkey1Beatrice Hammond1Linda Jailer1Janet Osei Konadu1Samuel Otieku Cyril1Noel Williams1
Isaac Aidoo Erzuah2- 1University of Health and Allied Sciences, Ho, Ghana
- 2University of Cape Coast, Cape Coast, Ghana
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Introduction: Vaccination has emerged as a critical strategy for combating the pandemic and preventing the emergence of new variants. Achieving population-level immunity through vaccination remains essential to reduce disease transmission and protect individuals Objectives: This study aimed to assess the knowledge, perceptions, and attitudes towards COVID-19 vaccines.Methods: A cross-sectional survey was conducted, utilizing simple random and stratified sampling methods to select 443 participants. The response rate was 99.5% (441). A structured questionnaire was used to collect the data. Univariate, bivariate, and multivariate analysis was done. The study was conducted in July, 2022.Results: Most participants were female, aged 18-65. Over half showed good COVID-19 knowledge, primarily obtained through media and family. Tertiary-educated respondents demonstrated significantly better understanding. While 53.0% believed post-vaccination infection was possible, 56.1% were willing to be vaccinated, though 53.0% wouldn't encourage others. Nearly 70% would refuse a second dose after experiencing reactions to the first. The statistical analysis revealed that COVID-19 knowledge levels were significantly associated with educational attainment (p=0.000), ethnic group (p=0.000), religious affiliation (p=0.015), and employment status (p=0.000), but not with gender (p=0.623) or marital status (p=0.117). The logistic regression model (p<0.00) revealed that tertiary education (AOR=30.204, p<0.000) and primary education (AOR=3.466, p<0.047) significantly increased likelihood of good COVID-19 knowledge compared to no education, while Akan ethnicity (AOR=0.161, p<0.012) was also a significant predictor.Targeting individuals with lower educational attainment can help bridge the knowledge gap and foster positive attitudes toward COVID-19 vaccines, ultimately contributing to effective virus control and improved public health outcomes.The study underscores the need for educational programs to improve vaccination uptake in Ghana, emphasizing adherence to public health measures.
Keywords: Africa, COVID-19 vaccines, Cross-sectional, knowledge, Practice, public health education
Received: 24 Oct 2024; Accepted: 15 Jul 2025.
Copyright: © 2025 Tackie, ASIEDU, Darkey, Hammond, Jailer, Konadu, Cyril, Williams and Erzuah. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: CHRISTIANA ASIEDU, University of Cape Coast, Cape Coast, Ghana
Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.