ORIGINAL RESEARCH article

Front. Public Health

Sec. Aging and Public Health

Volume 13 - 2025 | doi: 10.3389/fpubh.2025.1531101

Coexisting Frailty and Depression Associated with Low Physical Activity and Quality of Life in Saudi Community-Dwelling Older Adults: A Cross-Sectional Study Authors

Provisionally accepted
  • 1Prince Sattam Bin Abdulaziz University, Al-Kharj, Saudi Arabia
  • 2Jazan University, Jizan, Saudi Arabia

The final, formatted version of the article will be published soon.

Background: Frailty and depression are common conditions in older adults, but their coexistence and combined impact on physical activity and quality of life remain understudied, particularly in Saudi Arabia.Objective: To examine the independent associations of depression, frailty, and their coexistence with physical activity levels and quality of life among Saudi older adults.A cross-sectional study was conducted among 395 community-dwelling adults aged 60 years and older (mean age 66.4 ± 7.1 years, 60% women) in Saudi Arabia. Frailty was assessed using the FRAIL scale, depression using the Patient Health Questionnaire 9 (PHQ-9), physical activity using the Physical Activity Scale for the Elderly (PASE), and quality of life using the SF-12. Participants were categorized based on the results of FRAIL and PHQ-9 scale into four groups: coexisting frailty and depression, frailty only, depression only, or neither.The prevalence of coexisting frailty and depression was 8.6%. Participants with coexisting frailty and depression were more likely to be sedentary (OR = 4.37, 95% CI: 1.41-13.55, p = 0.011) compared to those without frailty or depression. Frailty only group (β = -3.55, p = 0.003) and coexisting frailty and depression (β = -2.55, p = 0.033) were significantly associated with lower physical quality of life. Depression, frailty, and their coexistence were all significantly associated with lower mental quality of life (p < 0.001 for all).The coexistence of frailty and depression in older adults is associated with a higher likelihood of sedentary behaviour and lower quality of life. These findings highlight the need for comprehensive geriatric assessments and targeted interventions addressing both physical and mental health in older adults.

Keywords: Frailty, Depression, physical activity, Quality of Life, Elderly

Received: 19 Nov 2024; Accepted: 29 Apr 2025.

Copyright: © 2025 Alhwoaimel, Alqahtani, Alshehri, Alhowimel and Alenazi. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Bader Alqahtani, Prince Sattam Bin Abdulaziz University, Al-Kharj, Saudi Arabia

Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.