ORIGINAL RESEARCH article
Front. Public Health
Sec. Infectious Diseases: Epidemiology and Prevention
Volume 13 - 2025 | doi: 10.3389/fpubh.2025.1542024
This article is part of the Research TopicThe interaction of chronic viral infections and SARS-CoV-2 infection and its effect on the COVID-19 pathogenesisView all 9 articles
Characteristics, management and factors associated with poor outcomes in COVID-19 patients in Burkina Faso: insights from a 2021 large-scale ambispective study
Provisionally accepted
Ariane Mamguem Kamga1*
Samiratou Ouédraogo2
Firmin Nongodo Kaboré3
Isidore Tiandiogo Traoré3Esperance Ouédraogo4Armel Poda5Arnaud Eric Diendéré6Dramane Kania3
Hermann Badolo2
Guillaume Sanou2Amariane Koné3Therese Samdapawindé Kagoné3Blahima Konaté4Rachel Médah3Nathalie de Rekeneire7
Boukary Ouédraogo6Oumar Billa1Gilles Paradis8Halidou Tinto9Tienhan Sandrine Dabakuyo-yonli1- 1Centre Georges François Leclerc, Dijon, France
- 2Institut National de Santé Publique (Burkina Faso), Ouagadougou, Burkina Faso
- 3MURAZ Center, Bobo-Dioulasso, Burkina Faso
- 4Centre National de la Recherche Scientifique et Technologique, Ouagadougou, Burkina Faso
- 5COMMUNE DE BOBO DIOULASSO, Bobo-Dioulasso, Burkina Faso
- 6Health Ministry ( Burkina Faso), Ouagadougou, Burkina Faso
- 7Expert System France S.A., Paris, France
- 8McGill University, Montreal, Canada
- 9Clinical Research Unit of Nanoro (CRUN), Nanoro, Burkina Faso
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Objectives: To assess treatment and identify predictive factors of worsening in COVID-19 patients. Methods: This study was ambispective (both prospective and retrospective) and part of a multidisciplinary, multicenter project designed to generate epidemiological, sociological and anthropological data about the COVID-19 epidemic in Burkina Faso. Medical records of patients admitted for COVID-19 at the hospitals of Ouagadougou and Bobo-Dioulasso from March 2020 to April 2021 were reviewed. To identify predictive factors of severe complications, we used Poisson regression models.Results: In total, 1511 patients were included, of whom 70% were aged ≤50 years, 59% were men and 97% were living in an urban area. Of the 86% of patients treated, 92.9% of them received the combo Azithromycin-hydroxychloroquine. A total of 78 (5.2%) patients experienced complications during hospitalization, and 49 (3.3%) patients died. Multivariate analysis identified patient's age, residence and comorbidity as factors associated with poor outcomes.Although most people had symptoms, most of them recovered without sequelae, and few patients had severe forms of disease. Age was a strong predictor of worse outcomes in this population.
Keywords: age, Comorbidity, COVID-19, complications, Treatment
Received: 09 Dec 2024; Accepted: 13 Jun 2025.
Copyright: © 2025 Mamguem Kamga, Ouédraogo, Kaboré, Traoré, Ouédraogo, Poda, Diendéré, Kania, Badolo, Sanou, Koné, Kagoné, Konaté, Médah, de Rekeneire, Ouédraogo, Billa, Paradis, Tinto and Dabakuyo-yonli. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Ariane Mamguem Kamga, Centre Georges François Leclerc, Dijon, France
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