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ORIGINAL RESEARCH article

Front. Public Health

Sec. Aging and Public Health

Volume 13 - 2025 | doi: 10.3389/fpubh.2025.1569179

This article is part of the Research TopicRe-visiting Risk Factors for Cardiometabolic Diseases: Towards a New Epidemiological FrontierView all 36 articles

Trends and Predictive Research on the Global Burden of Ischemic Heart Disease from 1990 to 2021: Analysis of the Global Burden of Disease Study 2021

Provisionally accepted
Pengpeng  LiangPengpeng Liang1Shizhao  ZhangShizhao Zhang1Mei  YanMei Yan2Hai  HuangHai Huang1Jinhua  KangJinhua Kang1Yue  LiYue Li1Guiyun  LiGuiyun Li1Hongyan  WuHongyan Wu1*
  • 1Shenzhen hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China
  • 2Jiangxi University of Traditional Chinese Medicine, Nanchang, Jiangxi Province, China

The final, formatted version of the article will be published soon.

To analyze trends in the global burden (GBD) of ischemic heart disease (IHD) over the past 30 years and health inequalities, as well as to predict the trends for the next 25 years. Methods: Data on the incidence, prevalence, mortality, Disability-Adjusted Life Years (DALYs), and risk factors for IHD were obtained from GBD 2021. Changing global, regional, and national trends from 1990 to 2021 were analyzed, accompanied by decomposition analysis. Potential for improvement was assessed using frontier analysis while conducting a regional risk factor ranking analysis. Joinpoint software and an age-period-cohort model were used to analyze IHD data further.Finally, future IHD trends were analyzed using the prediction models such as the Bayesian ageperiod-cohort analysis (BAPC) model.

Keywords: Ischemic Heart Disease, Global burden of disease, estimated annual percentage change, Risk factor analysis, Age-period-cohort, time trend

Received: 31 Jan 2025; Accepted: 02 Sep 2025.

Copyright: © 2025 Liang, Zhang, Yan, Huang, Kang, Li, Li and Wu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Hongyan Wu, Shenzhen hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China

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