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ORIGINAL RESEARCH article

Front. Public Health

Sec. Infectious Diseases: Epidemiology and Prevention

Volume 13 - 2025 | doi: 10.3389/fpubh.2025.1571217

COVID-19 Vaccine Uptake and Associated Factors Among High School Students in Lemi Kura Sub-City, Addis Ababa, 2022

Provisionally accepted
  • 1Faculity of Health Science, Rift Valley University, Adama, Oromia Region, Ethiopia
  • 2Ethiopian Public Health Institute, Addis Ababa, Ethiopia
  • 3Department of Public Health, College of Health Science, Salale University, Fithe, Ethiopia

The final, formatted version of the article will be published soon.

Background: COVID-19 remain as the major global health challenge, mostly affecting developing countries like Ethiopia who is facing low COVID-19 vaccination acceptance. This study aimed to assess the uptake of COVID-19 vaccine and its associated factors among high school students in Lemi Kura Sub-City, Addis Ababa. Methods: Institution based cross-sectional study was conducted at public high schools. Self-administered questionnaire were used to collect data from randomly selected high school students. We used Epi Info and SPSS software for data entry and analysis. Descriptive and multivariable logistic regression analysis were performed to identify factors associated with COVID-19 vaccination. Result: Of 802 participants (95% response rate), 46.2% were vaccinated. A total of 445 students (55.5%) had a good attitude, and 319 students (39.8%) had good knowledge regarding COVID-19 vaccine. Additionally, 625 students (78%) had undergone COVID-19 testing, and 286 students (35.7%) had history of infection. Factors significantly associated with vaccine uptake were good knowledge (AOR=2.1, 95%CI: 1.4-3.1), positive attitude (AOR=14.4, 95%CI: 9.5-22), prior testing (AOR=2.1, 95%CI: 1.2-3.7) and absence of negative information exposure (AOR=2.26, 95%CI: 1.3-3.9). Conclusion: The overall COVID-19 vaccine uptake was low. Knowledge, attitudes, prior COVID-19 testing, and exposure to misinformation significantly influence vaccine uptake among high school students. Improving awareness among the targeted population is essential to enhance vaccination rates.

Keywords: COVID-19 vaccine uptake, Risk factors, Lemi Kura Sub-city, Addis Ababa, Ethiopia

Received: 25 Feb 2025; Accepted: 15 Sep 2025.

Copyright: © 2025 Busa, Shuramu, Debela and Ferede. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence:
Jemal Beksisa Shuramu, jemubeksi@gmail.com
Sisay Abebe Debela, sisaya@yahoo.com

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