ORIGINAL RESEARCH article
Front. Public Health
Sec. Children and Health
Volume 13 - 2025 | doi: 10.3389/fpubh.2025.1590423
This article is part of the Research TopicMathematical Modeling of Medication NonadherenceView all 4 articles
A Study on the Construction of a Model for Sustained ICS Medication Adherence Behavior in Children with Asthma
Provisionally accepted
- 1Department of Pediatric Intensive Care Unit, Children’ s Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Chongqing, China
- 2Department of Infection Control, Second Affiliated Hospital of Army Medical University, Chongqing, China
- 3Department of Respiratory Medicine, Children’s Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Chongqing, China
- 4Department of Nursing, Children’s Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Chongqing, China
Select one of your emails
You have multiple emails registered with Frontiers:
Notify me on publication
Please enter your email address:
If you already have an account, please login
You don't have a Frontiers account ? You can register here
Objective: To develop a Sustained Adherence Behavior Model for ICS Medication in Children with Asthma. Method: Through literature review and semi-structured interviews, a questionnaire item pool was developed to assess the factors influencing the medication adherence behavior of asthma children using ICS. Expert consultation was conducted, involving two rounds of inquiries with experts, ultimately resulting in the development of the influence factors scale. The scale, along with the general situation survey of asthma children and the bronchial asthma medication adherence scale, was used to survey 370 asthma children who visited the outpatient department. Finally, a model of ICS medication adherence behavior for asthma children was established. Results: The positive coefficients of the two rounds of expert consultation were 90.5% and 95.2%, and the Kendall concordance coefficients were 0.384 and 0.278 (both P < 0.01). The Cronbach's α coefficient of the questionnaire was 0.925. The final asthma children's ICS medication adherence behavior influence factors scale consisted of 5 first-level items and 23 second-level items. Structural equation modeling analysis showed that the direct effects on medication adherence were behavioral intention (0.522), medication knowledge (0.193), and medication belief (0.181). The indirect effects were normative belief (0.161) and self-efficacy (0.140). The coefficient of determination (R²) for the influencing factors was 0.46 (P < 0.01). Conclusion: The behavioral model based on the Health Belief Theory effectively analyzes the factors influencing the ICS medication adherence behavior of asthma children, with the greatest impact coming from behavioral intention, followed by medication belief and medication knowledge.
Keywords: Asthma, Children, ICS (Inhaled Corticosteroids), sustained adherence behavior, Behavioral model
Received: 09 Mar 2025; Accepted: 02 Sep 2025.
Copyright: © 2025 Yan, Luo, Guo, Wu, Yin and Tang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Rong Guo, Department of Respiratory Medicine, Children’s Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Chongqing, China
Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.