ORIGINAL RESEARCH article

Front. Public Health

Sec. Aging and Public Health

Volume 13 - 2025 | doi: 10.3389/fpubh.2025.1591767

This article is part of the Research TopicFrom Vulnerability to Vigor: Innovative Approaches in Frailty and Healthy AgingView all 3 articles

Role of Frailty Index-Laboratory to predict COVID-19 mortality: a prospective study

Provisionally accepted
Elda De VitaElda De Vita1*Nicola VeroneseNicola Veronese2Giacomo GuidoGiacomo Guido1Luisa FrallonardoLuisa Frallonardo1Sergio CotugnoSergio Cotugno1Giorgia Manco CesariGiorgia Manco Cesari1Marinella CibelliMarinella Cibelli1Alessandra VignaAlessandra Vigna1Davide CapruzziDavide Capruzzi1Monica FiorellaMonica Fiorella1Carmen Rita SantoroCarmen Rita Santoro3Gaetano BrindicciGaetano Brindicci3Francesco Di GennaroFrancesco Di Gennaro1Annalisa SaracinoAnnalisa Saracino1
  • 1University of Bari Aldo Moro, Bari, Italy
  • 2University of Palermo, Palermo, Sicily, Italy
  • 3Azienda Ospedaliero Universitaria Consorziale Policlinico di Bari, Bari, Italy

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FI-LAB facilitates early identification of high-risk individuals, enabling healthcare providers to make informed decisions regarding patient management and resource allocation. Our study demonstrates the potential of FI-LAB to significantly enhance clinical outcomes by identifying patients who may require more intensive care and monitoring, thus optimizing the use of medical resources during critical periods.The implementation of FI-LAB in clinical practice could transform the approach to managing hospitalized COVID-19 patients, providing a reliable method for predicting patient mortality risk. This tool not only helps in better allocation of medical resources but also supports targeted interventions, potentially reducing mortality rates and improving overall patient care.Given the ongoing challenges posed by the COVID-19 pandemic, our research offers timely and valuable insights that could aid in the fight against this global health crisis. We believe that the broad applicability and

Keywords: Fraility, Fraility Index-Laboratory, Ageing, COVI-19, Morta lity

Received: 11 Mar 2025; Accepted: 13 May 2025.

Copyright: © 2025 De Vita, Veronese, Guido, Frallonardo, Cotugno, Cesari, Cibelli, Vigna, Capruzzi, Fiorella, Santoro, Brindicci, Di Gennaro and Saracino. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Elda De Vita, University of Bari Aldo Moro, Bari, Italy

Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.

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