ORIGINAL RESEARCH article
Front. Public Health
Sec. Aging and Public Health
Volume 13 - 2025 | doi: 10.3389/fpubh.2025.1601029
This article is part of the Research TopicStrategies to Improve Awareness and Management of Cancer Risk Factors and ScreeningsView all articles
Global, regional, and national burden of laryngeal cancer in middle-aged and elderly adults from 1990 to 2021: an analysis of age and sex differences and attributable risk factors
Provisionally accepted
- 1Linyi Central Hospital, Linyi, China
- 2The Second Hospital of Weihai City, Weihai, China
- 3The Second Hospital of Dalian Medical University, Dalian, China
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Background: Laryngeal cancer (LC) is a prevalent head and neck tumor, yet few studies quantify its disease burden and trends in risk factors of the age subgroup of middle-aged and elderly people (MAOP).: Based on Global Burden of Disease 2021 (GBD 2021) data, this study comprehensively assessed trends of disease burden in the age subgroup of LC in MAOP across 204 countries and regions from 1990 to 2021, covering incidence, prevalence, mortality, and disability-adjusted life years (DALYs). The estimated annual percentage change (EAPC) and joinpoint regression model were used to analyze the trends of disease burden and the changes in disease burden attributed to tobacco, alcohol, and occupational risk factors.
Keywords: Laryngeal cancer, Global burden of disease, Middle-aged, Elderly, Risk factors
Received: 27 Mar 2025; Accepted: 13 May 2025.
Copyright: © 2025 Xiao, Wang, Zhang, Wu and Yu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Shanying Wu, Linyi Central Hospital, Linyi, China
Bo Yu, The Second Hospital of Dalian Medical University, Dalian, China
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