ORIGINAL RESEARCH article
Front. Public Health
Sec. Environmental Health and Exposome
Volume 13 - 2025 | doi: 10.3389/fpubh.2025.1602454
Spatial patterns and temporal trends of tracheal, bronchus, and lung cancer attributed to particulate matter pollution in Asia and its 34 countries and territories, 1990 -2021
Provisionally accepted
- 1Shaoxing People's Hospital, Shaoxing, Zhejiang Province, China
- 2Department of Radiation Oncology, Zhuji Affiliated Hospital of Wenzhou Medical University, Shaoxing, Zhejiang Province, China
- 3Department of Medical Oncology, Zhuji Affiliated Hospital of Wenzhou Medical University, Shaoxing, Zhejiang Province, China
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Background: This study aimed to investigate the spatial and temporal variations of tracheal, bronchus, and lung cancer (TBLC) attributable to particulate matter pollution across 34 Asian countries and territories from 1990 to 2021.Methods: Disability-adjusted life years (DALYs) linked to ambient particulate-matter pollution (APMP) and household air pollution (HAP) were obtained from the Global Burden of Disease (GBD) 2021 dataset, and performed analyses stratified by location, gender, and age. Trends in agestandardised DALY rates (ASDRs) were quantified with Joinpoint regression. Decomposition analysis was applied to identify the contributions of population aging, population growth, and epidemiological changes to the alterations in DALYs.Results: From 1990 to 2021, APMP-related ASDR increased significantly in Asia, while HAPrelated ASDR declined. In 2021, East Asia recorded the greatest APMP-associated DALYs across five GBD regions, while both South Asia and East Asia bore the heaviest HAP-related burden. China reported the highest absolute DALYs for each pollutant. Population ageing and growth accounted for most of the increase in APMP-related DALYs in Asia, whereas epidemiological change chiefly explained the reduction in HAP-related DALYs. ASDRs were consistently higher in males, with wider sex disparities for APMP-related ASDR. Middle-aged and elderly populations were the most vulnerable age groups.Although TBLC burden attributable to HAP has fallen, disease linked to APMP remains a pressing public-health concern. Coordinated regional action and targeted interventions, particularly for men and older individuals, are essential to reduce pollution-driven TBLC across Asia.
Keywords: lung cancer, Ambient particulate matter pollution, household air pollution from solid fuels, Asia, Joinpoint regression model, Global burden of disease, Disability-adjusted life years
Received: 29 Mar 2025; Accepted: 11 Jul 2025.
Copyright: © 2025 Yang, Xuan, Wang, Lou and Yu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Feng Xuan, Department of Radiation Oncology, Zhuji Affiliated Hospital of Wenzhou Medical University, Shaoxing, Zhejiang Province, China
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