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REVIEW article

Front. Public Health

Sec. Children and Health

A Meta-Analysis of the Dose-Response Relationship Between Aerobic Exercise and Executive Function in Children

Provisionally accepted
yanhua  wangyanhua wang1qi  wangqi wang2min  yangmin yang2Wenwen  LiWenwen Li3*lu  wanglu wang2jiaqi  fanjiaqi fan2
  • 1Civil Aviation University of China, Tianjin, China
  • 2Yanshan University, Qinhuangdao, Hebei, China
  • 3Kunming University of Science and Technology, Kunming, China

The final, formatted version of the article will be published soon.

Objective: While existing meta-analyses of executive function focus on elderly and clinical pediatric populations, a substantial gap remains regarding typically developing children during this critical period. Our meta-analysis elucidates the dose-response relationship between aerobic exercise and executive function in this group, providing an evidence-based framework for exercise prescription and translational research. Methods: A comprehensive literature search was conducted to retrieve 4,135 relevant articles examining the impact of aerobic exercise on children's executive function from multiple databases, including PubMed, Embase, Web of Science, Cochrane Library, China Biology Medicine Database (CBM), CNKI, Wanfang, and VIP. The search period spanned from the inception of each database to December 2024. The quality of the included literature was assessed using the ROB 2 tool, and data analysis was conducted using RevMan 5.4 and Stata 16 software. Furthermore, the GRADE evidence quality evaluation tool was employed to assess the outcome indicators of the included studies. Results: A total of 19 articles were ultimately included, consisting of 17 English-language articles and 2 Chinese-language articles. All studies were randomized controlled trials (RCTs) involving a total of 18,650 children. The results indicated that the standardized mean differences (SMD) for the effects of aerobic exercise interventions on children's inhibitory control, working memory, and cognitive flexibility were as follows: SMD = 0.06, 95% CI (-0.09, -0.03) for inhibitory control; SMD = -0.01, 95% CI (-0.04, -0.02) for working memory; and SMD = -0.02, 95% CI (-0.01, -0.05) for cognitive flexibility. According to the GRADE evidence quality assessment, the three outcome indicators (inhibitory control, working memory, and cognitive flexibility) were rated as moderate quality. Conclusion: Single acute aerobic exercise sessions lasting less than 30 minutes demonstrate the most

Keywords: cognitive flexibility, Inhibitory Control, physical activity, subgroup analysis, working memory

Received: 09 Apr 2025; Accepted: 10 Nov 2025.

Copyright: © 2025 wang, wang, yang, Li, wang and fan. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Wenwen Li, ashley_li2023@163.com

Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.