ORIGINAL RESEARCH article
Front. Public Health
Sec. Environmental Health and Exposome
Volume 13 - 2025 | doi: 10.3389/fpubh.2025.1615288
This article is part of the Research TopicClimate Change, Air Pollution, and Health Inequality: Vulnerability of Marginalized PopulationsView all 16 articles
Association between meteorological factors, air pollutants and daily hospitalizations of coronary heart disease in rural areas of southern Xinjiang, China
Provisionally accepted
Xueying Han
Rulin Ma
Jia He
Bo YangSilin ChenXuelian WuDilimulati MuhetaerLanqing Ma
Shen ShijieXiaoxue LiPengxiang Zuo*
Heng Guo*- School of Medicine, Shihezi University, Shihezi, China
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Meteorological factors and air pollutants are two important factors affecting hospitalisation for coronary heart disease. The effects of meteorological factors and air pollutants on the risk of coronary heart disease hospitalisation and their interactions are understudied in rural areas with heavy particulate matter pollution at the edge of the desert in southern Xinjiang. In this study, patients with coronary heart disease who were hospitalized in Tangyi Town, Tumushuke City, Xinjiang Province, were selected as the study subjects, and the lagged effects of meteorological factors and air pollutants on the risk of coronary heart disease hospitalisation and their interactions were analysed by combining the distributional lag nonlinear model and the quasi-Poisson regression model. The results showed that the associations between meteorological factors and air pollutant concentrations with the risk of coronary heart disease hospitalisation both showed non-linear and lagged effects. There was an antagonistic effect between mean daily temperature and PM2.5 and PM10 on the effect of coronary heart disease hospitalisation, with RERIs of -0.73 (95% CI: -2.63, -0.04), and -1.14 (95% CI: -1.93, -0.60), respectively. The relative risk of coronary heart disease hospitalisation in the low-temperature, high PM10 concentration environment was 1.53 (95% CI: 1.09, 2.13). he risk of hospitalization for coronary heart disease is increased by 30% and 19% in environments with low humidity and high PM2.5 and PM10 concentrations, respectively. There are also interactions between particulate matter and gaseous pollutants and between different gaseous pollutants. This study suggests the need to necessity of management of multiple air pollutants and response to climate change, as well as the importance of implementing targeted preventive and control measures by the relevant authorities in according to meteorological and air pollution conditions, which can effectively reduce the hospitalization rate of patients with coronary heart disease.
Keywords: coronary heart disease, Meteorological factors, Air Pollutants, Hospitalizations, Interaction
Received: 21 Apr 2025; Accepted: 16 Jul 2025.
Copyright: © 2025 Han, Ma, He, Yang, Chen, Wu, Muhetaer, Ma, Shijie, Li, Zuo and Guo. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Pengxiang Zuo, School of Medicine, Shihezi University, Shihezi, China
Heng Guo, School of Medicine, Shihezi University, Shihezi, China
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