ORIGINAL RESEARCH article
Front. Public Health
Sec. Aging and Public Health
Volume 13 - 2025 | doi: 10.3389/fpubh.2025.1620261
Association Between Waist Circumference and Fatty Liver Disease in Elderly Population: A Cross-Sectional Study in Urumqi
Provisionally accepted
- 1新疆医科大学, Urumqi, China
- 2Department of Chronic Non-Communicable Disease Prevention and Control, Urumqi Center for Disease Control and Prevention(Urumqi Municipal Health Supervision Institute), Urumqi, China
Select one of your emails
You have multiple emails registered with Frontiers:
Notify me on publication
Please enter your email address:
If you already have an account, please login
You don't have a Frontiers account ? You can register here
Objective: This study aims to explore the correlation between waist circumference and the prevalence of fatty liver disease in the elderly population in Urumqi.Through cluster random sampling of healthcare institutions within the urban districts of Urumqi, a final cohort of 3,907 participants was enrolled from three institutions. In addition, the informed consent forms of the participants were obtained.Chi-square tests were used for univariate analysis between groups, and the data were divided into a training set and a test set in a 7:3 ratio. Variables were further screened using machine learning models such as random forest classifier and Lasso. Logistic regression and restricted cubic spline models were used to analyze the correlation 2 between waist circumference and fatty liver disease.The prevalence of fatty liver disease was 32.56%, with 31.54% in men and 33.40% in women. Multivariate logistic regression analysis showed that compared with non-central obesity, the risk of fatty liver disease in central obesity was significantly higher (OR=1.768, 95% CI: 1.481-2.112).The restricted cubic spline model analysis showed that the risk of fatty liver disease increased with waist circumference in the elderly population.In the total population and the male group, waist circumference and central obesity showed a nonlinear relationship, while in the female group, those below 75 years old, and those 75 and older, a linear relationship was observed. Conclusion: Controlling waist circumference is important for the prevention of fatty liver disease. The elderly population in Urumqi should pay attention to the risks posed by increasing waist circumference.
Keywords: elderly population, Waist Circumference, Fatty Liver, machine learning, Restricted cubic spline
Received: 29 Apr 2025; Accepted: 25 Jun 2025.
Copyright: © 2025 Zhang, Zhao and Sun. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Gaofeng Sun, Department of Chronic Non-Communicable Disease Prevention and Control, Urumqi Center for Disease Control and Prevention(Urumqi Municipal Health Supervision Institute), Urumqi, China
Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.