ORIGINAL RESEARCH article
Front. Public Health
Sec. Aging and Public Health
Volume 13 - 2025 | doi: 10.3389/fpubh.2025.1624310
This article is part of the Research TopicTransforming Dementia Caregiving Through Assistive TechnologiesView all 5 articles
Transforming Alzheimer's Disease Nursing: Integrating Holistic Care, Innovative Interventions, and Evidence-Based Practices for Enhanced Patient Outcomes
Provisionally accepted- 1Department of Geriatric Neurology, The Affiliated Brain Hospital of Nanjing Medical University, Nanjing 210029, China, nanjing, China
- 2Shanghai Fuyuan Elderly Care Service Co., Ltd., Shanghai, China, shanghai, China
- 3Mufushan Community Health Service Center, Nanjing, nanjing, China
- 4Jiangsu Province Hospital of Chinese Medicine, Jiangsu, China, jiangsu, China
Select one of your emails
You have multiple emails registered with Frontiers:
Notify me on publication
Please enter your email address:
If you already have an account, please login
You don't have a Frontiers account ? You can register here
Background: Alzheimer's disease (AD) represents a significant global healthcare challenge with increasing prevalence in aging populations. Traditional care models often focus primarily on symptom management with insufficient attention to holistic patient needs.Objectives: To evaluate the effectiveness of an integrated care approach combining holistic nursing interventions, innovative technologies, and evidence-based practices for enhanced patient outcomes in AD.Methods: A mixed-methods quasi-experimental study involving 248 AD patients across 9 healthcare facilities over 24 months. The intervention group (n=126) received an integrated care approach while the control group (n=122) received usual care. Outcomes were assessed using validated instruments at baseline and 6-month intervals.Results: Patients receiving integrated care showed significantly improved cognitive stability (ADAS-Cog change: 4.2±3.1 vs. 7.8±3.6 points, p<0.001), enhanced quality of life (QoL-AD improvement: 3.8±2.4 vs. -1.2±2.9 points, p<0.001), and reduced behavioral symptoms (NPI reduction: 15.4±10.2 vs. -6.8±12.5 points, p<0.001). Caregiver burden decreased significantly (ZBI reduction: 10.8±7.4 vs. -6.2±8.1 points, p<0.001).Conclusions: The integrated care approach demonstrates significant benefits across multiple domains, supporting its implementation for improving AD patient and caregiver outcomes.
Keywords: Alzheimer's disease, Holistic Nursing, Integrated Care, Person-centered care, Digital health technology, Caregiver support
Received: 07 May 2025; Accepted: 18 Aug 2025.
Copyright: © 2025 Fang, Cui, Zhao, Qian, Yong, Lan and Huang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: ChuanYing Huang, Department of Geriatric Neurology, The Affiliated Brain Hospital of Nanjing Medical University, Nanjing 210029, China, nanjing, China
Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.