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MINI REVIEW article

Front. Public Health

Sec. Substance Use Disorders and Behavioral Addictions

Nicotine Pouches and Youth: Emerging Patterns and Potential Cardiovascular Risks

Provisionally accepted
Shaun  Abid¹Shaun Abid¹1Abhinav  AggarwalAbhinav Aggarwal1*Freddy  Duarte LauFreddy Duarte Lau2Samdish  Sethi²Samdish Sethi²1Sumedh  Iyengar¹Sumedh Iyengar¹1Stuart  Zarich²Stuart Zarich²1
  • 1Yale New Haven Health System, New Haven, United States
  • 2Houston Methodist Hospital, Houston, Texas, United States

The final, formatted version of the article will be published soon.

The rapid rise in nicotine pouch use among teens and young adults signals a shift in nicotine consumption with significant public health implications. Marketed as discreet and "tobacco free," these products are often perceived as safer alternatives to smoking, yet their cardiovascular risks remain largely unexamined. Emerging concerns center on the high nicotine content, efficient bloodstream delivery, and growing rates of dual or poly-use with other nicotine products. Adolescents, in particular, face heightened vulnerability due to ongoing physiological development and increased addiction susceptibility. This review explores the potential cardiovascular consequences of nicotine pouch use in youth, emphasizing the urgency of evidence-based research to inform clinical guidance, regulatory action, and prevention strategies.

Keywords: Nicotine pouches, cardiovascular risk, adolescents, young adults, nicotine addiction, Tobacco harm reduction

Received: 14 Sep 2025; Accepted: 30 Oct 2025.

Copyright: © 2025 Abid¹, Aggarwal, Lau, Sethi², Iyengar¹ and Zarich². This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Abhinav Aggarwal, abhinav.aggarwal@yale.edu

Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.