SYSTEMATIC REVIEW article
Front. Public Health
Sec. Environmental Health and Exposome
Volume 13 - 2025 | doi: 10.3389/fpubh.2025.1643134
This article is part of the Research TopicThe Impact of Geo-Spatiality and Pollution on the Chronic Health ConditionsView all articles
Outdoor Air Pollution and Hospitalizations for Ischemic Heart Disease: A Systematic Review and Meta-Analysis
Provisionally accepted
Mailidan Maimaitiniyazi
Abuduwupuer haibier
Muyesaier MaimaitiniyaziMeiheliya MaisutiAilifeire AihaitiTuersunayi YisimitiNijiati Muyesai*- People's Hospital of Xinjiang Uygur Autonomous Region, Ürümqi, China
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Objective: To evaluate the association between six major outdoor air pollutants (i.e., PM2.5, PM10, NO2, SO2, CO, and O3) and the risk of ischemic heart disease (IHD)-attributable hospitalization, so as to provide potential scientific evidence for the formulation of clinical and public health policies. Methods: With access to PubMed and Web of Science databases (up to March 2025), present meta-analysis screened and included 17 high-quality studies (3 cohort studies, 1 case-control study, and 13 time-series studies) covering 28,186,905 cases hospitalized for IHD. This study focused on the determination of the impact of air pollutant concentration changes on IHD-attributable hospitalization risk through statistical analysis using Stata 16.0. In addition, sensitivity analyses and funnel plots were employed to assess the stability and publication bias. Results: Meta-analysis revealed the following associations between air pollutants and IHD-
Keywords: Ischemic Heart Disease, hospitalization risk, Meta-analysis, Outdoor air pollutants, relative risk
Received: 08 Jun 2025; Accepted: 15 Jul 2025.
Copyright: © 2025 Maimaitiniyazi, haibier, Maimaitiniyazi, Maisuti, Aihaiti, Yisimiti and Muyesai. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Nijiati Muyesai, People's Hospital of Xinjiang Uygur Autonomous Region, Ürümqi, China
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