Epidemiological Characteristics of Human Psittacosis in Guangdong Province, China, 2019-2024

Yali Zhuang¹Yu Wang¹Shujun Zhang²Chengcong Li³Ting Hu¹Chenhuan Zhang⁴Zenglong Huang⁵Qiuhong Zeng⁶Ze Liu⁷Canhui Weng⁸Lixian Luo⁹Mingqi Zou¹⁰Jing Zeng¹Wenting Guo¹Wenyan Li¹Min Kang^1*Aiping Deng^1*

• ¹Guangdong Provincial Center for Disease Control and Prevention, Guangzhou, China
• ²Kaiping Center for Disease Control and Prevention, Kaiping, China
• ³Maoming Municipal Center for Disease Control and Prevention, Maoming, China
• ⁴Yantian District Center for Disease Control and Prevention of Shenzhen, Shenzhen, China
• ⁵Qujiang Center for Disease Control and Prevention, Shaoguan, China
• ⁶Heyuan Center for Disease Control and Prevention, Heyuan, China
• ⁷Chaoan Center for Disease Control and Prevention, Chaozhou, China
• ⁸Daya Bay Economic and Technological Development Zone Center for Disease Control and Prevention, Huizhou, China
• ⁹Chaonan Center for Disease Control and Prevention, Shantou, Guangdong, Chaoan, China
• ¹⁰Meizhou Municipal Center for Disease Control and Prevention, Meizhou, China

ABSTRACT Background: Psittacosis is a non-statutory infectious disease and receives relatively low attention in China. Since 2019, the incidence of psittacosis in Guangdong Province has been continuously increasing. Therefore, it is necessary to understand the epidemiological characteristics, providing a basis for optimizing psittacosis prevention and control. Methods: This study included psittacosis cases reported in Guangdong Province from 2019 to 2024. Data were collected and a retrospective survey was conducted. The spatiotemporal distribution, clinical manifestations and epidemiological exposure histories were analyzed. Logistic regression model was used to explored the risk factors for psittacosis pneumonia. Results: A total of 435 psittacosis cases were reported in Guangdong Province. It demonstrated an overall increasing trend in the incidence rate, with cases predominantly occurring in winter and spring. Nansha District in Guangzhou (p<0.001), Boluo in Huizhou (p<0.001) and Shunde in Foshan (p=0.001) were identified as hotspots for psittacosis. The incidence rate of psittacosis was higher in males (χ2=17.26, p<0.001) and in the 50-79 age group (χ2=123.45, p<0.001). Univariate regression analysis showed that underlying diseases are a risk factor for psittacosis pneumonia [OR (95%CI) = 2.47(1.42, 3.31), p=0.01]. There were 162 cases with a history of epidemiological exposure, but only 42 cases (25.93%) used protective measures. Conclusion: The incidence of psittacosis has been increasing in Guangdong Province recently, posing a threat to individuals with poultry exposure. In the future, it is suggested to enhance the monitoring of individuals with daily contact with poultry, particularly for the elderly, in winter and spring.