Your new experience awaits. Try the new design now and help us make it even better

ORIGINAL RESEARCH article

Front. Public Health

Sec. Public Mental Health

This article is part of the Research TopicPrediction of trauma-related disorders: Identifying pre-exposure factors, neurobiological mechanisms, and their impact on future adaptation in a comprehensive analysis of risk and resilienceView all 3 articles

Post-traumatic stress disorder in French Guiana: Prevalence and risk factors in the general population

Provisionally accepted
Mathieu  NacherMathieu Nacher1*astrid  van-melleastrid van-melle1estelle  thomasestelle thomas1Johanna  PavieJohanna Pavie2blandine  solignatblandine solignat3Imane  BenradiaImane Benradia4deborah  sebbanedeborah sebbane4eva  aernouteva aernout4jean-luc  roelandtjean-luc roelandt4caroline  janviercaroline janvier3francois  lairfrancois lair3vincent  bobilliervincent bobillier3
  • 1INSERM CIC1424 Centre d'Investigation Clinique Antilles Guyane, Cayenne, French Guiana
  • 2Plateforme Rétablissement, Groupe SOS, Cayenne, French Guiana
  • 3CHU de Guyane, Cayenne, French Guiana
  • 4Centre collaborateur de l'OMS pour la recherche et la formation en santé mentale – CCOMS. Service de l'EPSM Lille-Métropole, Lille, France

The final, formatted version of the article will be published soon.

Background With regards to post-traumatic stress disorder, the context of French Guiana —frequent violence and intense immigration of persons from areas where traumatic events are common— may lead to a different epidemiology of PTSD relative to mainland France. In the absence of prior data, we aimed to estimate the overall prevalence of PTSD in the general population of French Guiana and its prevalence in different sociodemographic groups. Methods A cross sectional survey was conducted between March and August 2021 interviewing 881 persons aged >17 years. Results The global prevalence was 7.6 [95% CI=5.9-9.5]. After adjusting for potential confounding among the sociodemographic variables only Female sex (adjusted prevalence ratio (aPR)=2.1 (IC95=1.2-3.6), P=0.006), being a student (aPR=2.4 (IC95=1.0-5.6), P=0.05), being from Suriname (aPR=5.8 (1.0-33.4), P=0.05), not having completed primary education (aPR=3.4 (IC95=1.3-8.9), P=0.01), and being separated or divorced (aPR=3 (IC95=1.1-8.2), P=0.02) were significantly associated with PTSD. Only 31 of 67 persons with PTSD (46.3%) sought care. Overall, 21 of 67 (31.3%) declared having taken treatment for their symptoms and 29/67 (43.3%) took alternative treatments, mostly plant-based traditional medicine. Among the 394 persons having lived through an unusual traumatic event 67 (17%) developed PTSD. Conclusions We show that the prevalence is 10 times greater than in mainland France, and that behind this, there are great differences between origins, sexes, and age groups. We also show that the majority of persons do not care for their symptoms and that those who do often combine western and traditional medicine. The results emphasize the need for culturally sensitive screening and care.

Keywords: Post Traumatic Stress Disorder, Migration, age, gender, French Guiana

Received: 17 Jul 2025; Accepted: 27 Oct 2025.

Copyright: © 2025 Nacher, van-melle, thomas, Pavie, solignat, Benradia, sebbane, aernout, roelandt, janvier, lair and bobillier. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Mathieu Nacher, mathieu.nacher66@gmail.com

Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.