ORIGINAL RESEARCH article
Front. Public Health
Sec. Injury Prevention and Control
Volume 13 - 2025 | doi: 10.3389/fpubh.2025.1675607
Global Burden and Trends of High alcohol use-Related Injuries from 1990 to 2030: A Comprehensive Assessment of Self-harm and interpersonal violence, Transport Injuries, and Unintentional Injuries Using Global Burden of Disease
Provisionally accepted
- 1Wenzhou Medical University, Wenzhou, China
- 2Wenzhou Medical University School of Laboratory Medicine and Life Sciences, Wenzhou, China
- 3Tongji University Affiliated Shanghai Pulmonary Hospital, Shanghai, China
- 4Wenzhou Medical University Eye Hospital, Wenzhou, China
- 5Capital Medical University Beijing Ditan Hospital, Beijing, China
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Background High alcohol use (HAU) is a major global public health concern, contributing to injuries such as Self-harm and interpersonal violence (SIV), Transport injuries (TI), and Unintentional injuries (UII). However, comprehensive global assessments of HAU-related injury burden remain limited. Methods Using data from Global Burden of Disease (GBD) 2021, we estimated HAU-related mortality and disability-adjusted life years (DALYs) from 1990 to 2021 across 204 countries and regions. We analyzed trends in Age-Standardized Disability-Adjusted Life Years Rate (ASDR) and Age-Standardized Mortality Rate (ASMR), examined Socio-demographic index (SDI) disparities, and employed age-period-cohort (APC) and Bayesian APC (BAPC) models for future projections. Frontier analysis identified countries with the greatest potential for burden reduction. Results Despite the decline in ASDR and ASMR in overall global injuries, Low-middle SDI regions continue to experience increasing SIV and TI burdens (ASDR rose from 57.25 to 70.55; 25.08 to 30.8 respectively), while UII remains high in High-middle and High SDI countries (The ASDR were 57.94 and 59.12 respectively). Young adults and the elderly bear the greatest burden. BAPC projections indicate that China, India, and several high-burden nations will see further increases in DALYs and ASDR by 2030, highlighting the need for urgent interventions. Conclusion Targeted policy measures, such as raising the legal drinking age, strengthening alcohol control for young people in Low and Low-middle-SDI regions, and enhancing elderly healthcare services in High-SDI regions, are essential to mitigate HAU-related injuries. Evidence-based, SDI-adapted strategies can significantly reduce this burden.
Keywords: high alcohol use, Self-harm and interpersonal violence, Transportinjuries, unintentional injuries, GBD, SDI
Received: 29 Jul 2025; Accepted: 25 Sep 2025.
Copyright: © 2025 Yuan, Chen, Sun, Zheng, Kang, Lou and Zheng. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Qiheng Yuan, yqh1607117941@163.com
Yutong Kang, kangyutong0601@163.com
Yong-Liang Lou, lyl@wmu.edu.cn
Meiqin Zheng, zmq@eye.ac.cn
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