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ORIGINAL RESEARCH article

Front. Public Health

Sec. Health Economics

Volume 13 - 2025 | doi: 10.3389/fpubh.2025.1683074

This article is part of the Research TopicInnovative Value-Based Medicine: Lessons from China's Healthcare EvolutionView all 16 articles

Study on the Relationship between Buyer Market Power, Spatial Spillover Effect, and Profit in China's Pharmaceutical Industry

Provisionally accepted
Guanyi  YuGuanyi Yu1Lei  WuLei Wu1*Heng  ChenHeng Chen1Zhengliang  DingZhengliang Ding2
  • 1Harbin Engineering University, Harbin, China
  • 2Party School of Heilongjiang Provincial Committee of CPC, harbin, China

The final, formatted version of the article will be published soon.

Abstract: Previous studies have extensively explored industrial innovation, but the impact of downstream buyer market power on upstream industries remains underexamined. Using a spatial Durbin model and data from China's medical and pharmaceutical sectors (2001–2021), we analyze how buyer market power affects pharmaceutical industry profitability. Key findings include: (1) Local buyer market power reduces local pharmaceutical profitability and may also negatively affect other regions through spatial spillover, though this spillover effect is weak. (2) Stronger regional economic ties amplify the impact of local medical industry power on pharmaceutical profitability. (3) Supplier countervailing power can mitigate the negative effects of buyer power on pharmaceutical profits. (4) Buyer market power significantly harms pharmaceutical profitability in western China and low capital-intensity sectors, but not in eastern or central regions and high capital-intensity sectors. (5) Asset specificity intensifies the negative impact of buyer power, while larger firm size helps reduce it. (6) Buyers can lower pharmaceutical profitability by reducing R&D investment. This study contributes to industrial organization theory by revealing how downstream buyer power affects upstream profitability. It expands empirical methods by incorporating spatial econometrics and offers policy suggestions for improving pharmaceutical industry performance from a vertical chain perspective.

Keywords: Buyer market power, seller countervailing power, Profit, spatial Durbin model, Spatial spillover effect

Received: 11 Aug 2025; Accepted: 20 Oct 2025.

Copyright: © 2025 Yu, Wu, Chen and Ding. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Lei Wu, wulei@hrbeu.edu.cn

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