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ORIGINAL RESEARCH article

Front. Public Health

Sec. Health Economics

Volume 13 - 2025 | doi: 10.3389/fpubh.2025.1683415

This article is part of the Research TopicInnovative Value-Based Medicine: Lessons From China’s and APAC’s Healthcare Evolution, Volume IIView all articles

Divergent Trends and Regional Disparities in PM2.5 and O3 Health Economic Burdens in China, 2013–2023: An Integrated Assessment with Policy Implications

Provisionally accepted
Ziqi  TangZiqi Tang1Xialing  SunXialing Sun1*Shichao  ZhuShichao Zhu2Chongbao  RenChongbao Ren3*Xiaotong  QieXiaotong Qie4Jiaxi  WuJiaxi Wu4*
  • 1Shandong Second Medical University, Weifang, China
  • 2Hebei University of Engineering, Handan, China
  • 3China Special Equipment Inspection and Research Institute, Beijing, China
  • 4Beijing Institute of Petrochemical Technology, Beijing, China

The final, formatted version of the article will be published soon.

Utilising China's air quality monitoring data from 2013 to 2023, this study employs spatial autocorrelation analysis and health impact assessment methodologies to quantify the health economic costs and temporal trends of PM2.5 and O3 pollution across mainland China. Results indicate a substantial decline in PM2.5-attributable mortality over the study period. With 0 and 15 μg/m3 taken as the reference concentrations, all-cause mortality decreased by 47.41% (233,173 cases) and 65.55% (240,448 cases), respectively. Cardiovascular disease mortality declined by 47.71% (56,086 cases) and 65.75% (57,504 cases), while respiratory disease mortality reduced by 46.97% (38,519 cases) and 65.27% (40,055 cases). Conversely, O3-related mortality exhibited a significant upward trend. At reference concentrations of 0 and 60 μg/m3, all-cause mortality increased by 24.25% (365,084 cases) and 79.70% (372,724 cases), respectively. Cardiovascular mortality rose by 25.43% (80,056 cases) and 81.52% (77,497 cases), and respiratory mortality increased by 15.46% (98,620 cases) and 64.54% (163,165 cases). Spatially, health economic costs and their GDP proportions for both pollutants followed a high distribution in the east and a low distribution in the west. Shandong, Henan and Jiangsu were the top regions for PM2.5-related economic costs, with Henan, Hebei and Tianjin exhibiting the highest GDP ratios. For O3, Guangdong, Jiangsu and Shandong incurred the greatest economic costs, while Henan, Hebei and Gansu showed the highest GDP proportions. These findings underscore the divergent trends in PM2.5 and O3 health impacts and provide critical evidence for targeted air pollution control strategies in China.

Keywords: PM2.5, O3, health economic burdens, spatial autocorrelation, China

Received: 11 Aug 2025; Accepted: 14 Oct 2025.

Copyright: © 2025 Tang, Sun, Zhu, Ren, Qie and Wu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence:
Xialing Sun, sunxialing0328@163.com
Chongbao Ren, renchongbao@csei.org.cn
Jiaxi Wu, wujiaxi0427@163.com

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