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ORIGINAL RESEARCH article

Front. Public Health

Sec. Occupational Health and Safety

This article is part of the Research TopicNurse Fatigue: Investigating Burnout, Health Risks, and Prevention StrategiesView all 22 articles

Latent profile analysis of change fatigue and its relationship with work withdrawal behavior in clinical nurses: a multicenter study

Provisionally accepted
Xin  MaXin Ma1*Yi  LiYi Li2Qiu-ping  DingQiu-ping Ding1Ya-ping  ZhangYa-ping Zhang1Zhi-qin  BaiZhi-qin Bai1Yan-guang  SuYan-guang Su1Jia-cheng  ShenJia-cheng Shen1Jun-jun  HuangJun-jun Huang1Siyi  YangSiyi Yang1
  • 1Huzhou Central Hospital, Affiliated Central Hospital of Huzhou University, Huzhou, China
  • 2Kunshan Hospital of Integrated Chinese and Western Medicine, kunshan, China

The final, formatted version of the article will be published soon.

Objective To investigate the latent categories of clinical nurses' change fatigue profiles, analyze the factors influencing these categories, and explore their correlation with work withdrawal behavior. Methods A total of 733 nurses from various provinces and cities across China were selected as research subjects using convenience sampling. The subjects were investigated using a general information questionnaire, a change fatigue scale, and a work withdrawal behavior scale. The data were analyzed and tested through factor analysis and pairwise comparison. Results Clinical nurses' change fatigue was categorized into three latent profiles: high, medium, and low change fatigue groups. Significant differences were observed in education level (χ2=20.968, P<0.001), hospital level (χ2=12.021, P=0.017), self-assessed work atmosphere (χ2=32.081, P<0.001), self-assessed workload (χ2=44.677, P<0.001), and coping style (χ2=13.346, P<0.001) across the three groups of nurses. Logistic regression analysis indicated that education level, hospital level, self-assessed work atmosphere, workload, and coping style were influencing factors of change fatigue (P<0.05). Nurses in the high change fatigue group exhibited significantly higher work withdrawal behavior than those in the medium group (P < 0.01), which was, in turn, significantly higher than in the low fatigue group (P < 0.01). Conclusions For nurses experiencing change fatigue, which is closely linked to work withdrawal, managers should implement targeted interventions. These include optimizing the work environment, rational task allocation, and offering psychological support, all aimed at reducing withdrawal behaviors and promoting job stability.

Keywords: Nurses, Change fatigue, Work withdrawal behavior, Latent profile, InfluencingFactors, relevance

Received: 29 Aug 2025; Accepted: 03 Nov 2025.

Copyright: © 2025 Ma, Li, Ding, Zhang, Bai, Su, Shen, Huang and Yang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Xin Ma, 997353858@qq.com

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