ORIGINAL RESEARCH article
Front. Public Health
Sec. Occupational Health and Safety
This article is part of the Research TopicNurse Fatigue: Investigating Burnout, Health Risks, and Prevention StrategiesView all 22 articles
Latent profile analysis of change fatigue and its relationship with work withdrawal behavior in clinical nurses: a multicenter study
Provisionally accepted- 1Huzhou Central Hospital, Affiliated Central Hospital of Huzhou University, Huzhou, China
 - 2Kunshan Hospital of Integrated Chinese and Western Medicine, kunshan, China
 
Select one of your emails
You have multiple emails registered with Frontiers:
Notify me on publication
Please enter your email address:
If you already have an account, please login
You don't have a Frontiers account ? You can register here
Objective To investigate the latent categories of clinical nurses' change fatigue profiles, analyze the factors influencing these categories, and explore their correlation with work withdrawal behavior. Methods A total of 733 nurses from various provinces and cities across China were selected as research subjects using convenience sampling. The subjects were investigated using a general information questionnaire, a change fatigue scale, and a work withdrawal behavior scale. The data were analyzed and tested through factor analysis and pairwise comparison. Results Clinical nurses' change fatigue was categorized into three latent profiles: high, medium, and low change fatigue groups. Significant differences were observed in education level (χ2=20.968, P<0.001), hospital level (χ2=12.021, P=0.017), self-assessed work atmosphere (χ2=32.081, P<0.001), self-assessed workload (χ2=44.677, P<0.001), and coping style (χ2=13.346, P<0.001) across the three groups of nurses. Logistic regression analysis indicated that education level, hospital level, self-assessed work atmosphere, workload, and coping style were influencing factors of change fatigue (P<0.05). Nurses in the high change fatigue group exhibited significantly higher work withdrawal behavior than those in the medium group (P < 0.01), which was, in turn, significantly higher than in the low fatigue group (P < 0.01). Conclusions For nurses experiencing change fatigue, which is closely linked to work withdrawal, managers should implement targeted interventions. These include optimizing the work environment, rational task allocation, and offering psychological support, all aimed at reducing withdrawal behaviors and promoting job stability.
Keywords: Nurses, Change fatigue, Work withdrawal behavior, Latent profile, InfluencingFactors, relevance
Received: 29 Aug 2025; Accepted: 03 Nov 2025.
Copyright: © 2025 Ma, Li, Ding, Zhang, Bai, Su, Shen, Huang and Yang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Xin  Ma, 997353858@qq.com
Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
