ORIGINAL RESEARCH article
Front. Public Health
Sec. Infectious Diseases: Epidemiology and Prevention
The trend analysis of HIV and other sexually transmitted infections among women of childbearing aged 15 to 49 years from 1990 to 2021 and its Forecasting from 2022 to 2030
Provisionally accepted
- 1Fujian University of Traditional Chinese Medicine, Fuzhou, China
- 2Xiamen Center for Disease Control and Prevention, Xiamen, China
- 3Fujian Medical University Union Hospital, Fuzhou, China
- 4People's Hospital of Fujian Province, Fuzhou, China
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Background HIV and other sexually transmitted infections (STIs) among women of childbearing age need in-depth research because of the physiological characteristics and their disadvantages in obtaining equal health rights. We intend to present the burden of disease worldwide from 1990 to 2021 using data from the Global Burden of Disease (GBD) study and forecast the DALYs from 2022 to 2030. Methods Using the 2021 GBD study, we researched the average annual percentage change (AAPC) of HIV and other STIs in incidence, prevalence, disability-adjusted life years (DALYs) rates for women of childbearing age aged 15 to 49 years across different age groups, sociodemographic index (SDI) regions, and nations. We used statistical Autoregressive Integrated Moving Average (ARIMA) models to forecast. Results In 2021, there were 670804 new AIDS cases in women of childbearing age globally, with a decrease in age-standardised incidence rate (AAPC -1.94,-2.21 to -1.67) and an increase in age-standardised DALYs rate (AAPC 1.67,1.20 to 2.14) from 1990 to 2021. There were 2,8651,4651 new other STIst cases with an increase in age-standardised incidence rate (AAPC 0.12,0.09 to 0.14) and a decrease in age-standardised DALYs rate (AAPC-0.15,-0.18 to -0.11). The largest increase in age-standardised incidence rate of HIV occurred in Oceania from 1990 to 2021. The SDI trends were the opposite of age-standardised incidence rate and age-standardised DALYs rate for HIV and other STIs among women of childbearingage. The STI and HIV epidemics are interdependent. Women aged 30-34 years were the group with the highest incidence and DALY rates. Trichomoniasis and chlamydia account for the majority of cases of other STIs. The DALYs rate of HIV showed a downward trend, and the DALYs rate of other STIs showed an upward trend from 2022 to 2030. Conclusions Our study investigated the status of HIV and other STIs in women of childbearing age. The DALYs rate of HIV increased. The incidence rate of other STIs rised and the number of cases was so high that the harm could not be ignored. All sectors of the global community should pay attention to the prevention and control of STIs among women of childbearing age.
Keywords: aids, Sexually transmitted infection, Childbearing age, Global burden of disease, disability-adjustedlifeyears
Received: 09 Sep 2025; Accepted: 27 Nov 2025.
Copyright: © 2025 Lin, Lin, Chen, Xie, Zhou, Xiao and Wang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Xiaohong Wang
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