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ORIGINAL RESEARCH article

Front. Public Health

Sec. Infectious Diseases: Epidemiology and Prevention

This article is part of the Research TopicAdvances in Mathematical Modelling for Infectious Disease Control and PreventionView all 5 articles

Frequency-Aligned Loss and Spectral Filtering Improve Long-Range Influenza Forecasting

Provisionally accepted
Tianyi  FengTianyi Feng1*Chunyan  LuoChunyan Luo2Yu  HuangYu Huang1
  • 1Department of Rehabilitation, West China Hospital Sichuan University JinTang Hospital. Jintang First People's Hospital, Chengdu, China
  • 2Jilin Sport University, Changchun, China

The final, formatted version of the article will be published soon.

Background: Long-horizon forecasts of seasonal influenza remain limited by (i) rapid error growth beyond a few weeks, (ii) entanglement of persistent seasonal cycles with transient outbreaks, and (iii) training objectives that ignore strong autocorrelation in future incidence labels. Methods: We introduce a frequency-aware pipeline that couples a Spectral Adaptive Filtering Network with a Frequency-Aligned Direct Loss. The backbone first isolates stable global spectral bands and then builds window-specific cross-covariate filters to capture transient events; this convex loss function simultaneously supervises prediction results in both the time domain and the approximated decorrelated frequency domain, effectively reducing bias caused by autocorrelation without sacrificing point accuracy. Results: On 49 US states (2010–2020), 10 HHS and 9 Census regions (2002–2020), the proposed model lowers MSE by 6–15% and MAE by 2-20% at 24-week horizons versus six recent baselines while maintaining interpretable band-pass responses that match annual and semi-annual epidemiological periodicities. Ablation and sensitivity analyses confirm that joint time–frequency supervision and dual static–dynamic filtering are both required for peak performance. Conclusions: Explicit spectral decomposition coupled with autocorrelation-aware training offers a principled route to stable, interpretable long-range influenza forecasting; the modular objective can be plugged into alternative architectures to gain similar error reductions.

Keywords: Seasonal-influenza forecasting, Frequency-aligned loss, Spectral adaptive filtering, Long-horizon epidemic prediction, Long-horizon forecast

Received: 14 Oct 2025; Accepted: 05 Dec 2025.

Copyright: © 2025 Feng, Luo and Huang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Tianyi Feng

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