REVIEW article
Front. Soft Matter
Sec. Biological Soft Matter
Volume 5 - 2025 | doi: 10.3389/frsfm.2025.1683717
This article is part of the Research TopicFrontiers in Soft Matter: Chief Editor InsightsView all articles
Skin Wound Healing Part I: Ancestral and Modern Medicines for the Development of New Technologies
Provisionally accepted
Amanda Guadalupe Romero1*
Andrea Paola Rodriguez1*
Silvia Noemi Kozuszko1Lucca Comotti1
Kenichi Nagano2Carmelo José Felice1
Naoki Katase2- 1Universidad Nacional de Tucuman, San Miguel de Tucumán, Argentina
- 2Nagasaki Daigaku - Sakamoto Campus 1, Nagasaki, Japan
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The human body, once regarded primarily as a spiritual vessel, is now understood as a highly complex biological system governed by intricate cellular and molecular processes. As civilizations and technologies have evolved, so too have the methodologies, materials, and epistemologies surrounding wound care. From herbal applications in ancient cultures to the development of bioengineered dressings in contemporary medicine, the field of wound healing reflects a continuous trajectory of innovation and adaptation. This review presents a concise overview of wound management practices across diverse cultural contexts, highlighting the contributions of ancestral knowledge systems. It further examines the current landscape of wound dressing technologies, with particular emphasis on soft materials engineered, such as polymers, gels, and foams, to optimize healing outcomes in both acute and chronic wounds. In seeking deeper integration of ancestral knowledge into biomedical innovation, this review explores clinical trials, patent activity, regulatory standards, and epistemological considerations related to medicinal plant applications. By honoring origin and embracing plural knowledge systems, we aim to advance the development of wound care nanotechnologies that are not only scientifically robust but also culturally inclusive, ethically grounded, and accessible across diverse healthcare settings.
Keywords: Wound Healing, Herbal Medicine, Tissue Engineering, Acute and chronic wounds, Nanotechnology
Received: 11 Aug 2025; Accepted: 21 Oct 2025.
Copyright: © 2025 Romero, Rodriguez, Kozuszko, Comotti, Nagano, Felice and Katase. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Amanda Guadalupe Romero, guaromero@gmail.com
Andrea Paola Rodriguez, aprodriguez@herrera.unt.edu.ar
Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.