432 news posts in Health

Health

17 Jan 2023

From pylons to pandas: 5 Frontiers articles you won’t want to miss

by Angharad Brewer Gillham, Frontiers science writer Image/Shutterstock.com At Frontiers, we bring some of the world’s best research to a global audience. But with tens of thousands of articles published each year, many often fly under the radar. Here are just five amazing papers you may have missed. Building better-looking pylons Pylons help support essential amenities – but they can be an eyesore. Italian scientists led by Dr Luca Di Angelo at University of L’Aquila investigated the best way to build a pylon with less visual impact on the landscape. As visual impact is subjective, reducing it requires consultation with residents who will see the pylons every day. But designs invented by residents without technical knowledge may not be able to meet safety standards. Di Angelo and colleagues used the development of new electrical pylons in the coastal regions of Italy to test a novel method of integrating visual impact minimization with the design process. They identified shapes which were related to the geography and culture of the area and streamlined enough for pylon design, and surveyed Italians from different coastal regions to determine which shapes were considered most recognizable and representative. A sail was chosen, and models were developed […]

Health

12 Jan 2023

Simple blood test shows promise for screening common and dangerous pregnancy complications

By Angharad Brewer Gillham, Frontiers science writer Image/Shutterstock.com Scientists find that short-chain fatty acids in blood can be used as biomarkers in testing for dangerous pregnancy complications such as pre-eclampsia, gestational diabetes and intrahepatic cholestasis of pregnancy. Scientists at Ningbo University, China have identified biomarkers that could provide an early warning system for three common and dangerous pregnancy complications: pre-eclampsia, gestational diabetes, and a liver condition called intrahepatic cholestasis. All three conditions are dangerous; early diagnosis and treatment is key to preventing poor outcomes and lifelong consequences. Their causes are not fully understood, and nor is their connection to the gut microbiome, which is affected by pregnancy and pregnancy-related conditions. A team led by Dr Siqian Chen at the Affiliated Hospital of Medical School decided to investigate whether specific changes in the microbiome — detected using levels of short-chain fatty acids, metabolites which are produced following the fermentation of microbiota — could be used as biomarkers for pregnancy complications. “We analyzed and correlated the distribution of short-chain fatty acids during normal pregnancy and during three specific types of complicated pregnancy, gestational diabetes, pre-eclampsia, and intrahepatic cholestasis,” said Dr Rongrong Xuan, senior author of the study, published today in Frontiers in […]

Health

09 Jan 2023

Eating almonds daily boosts exercise recovery molecule by 69% among ‘weekend warriors’

By Mischa Dijkstra, Frontiers science writer A new randomized controlled trial showed that participants who daily ate 57g almonds over four weeks had a 69% higher level of the beneficial oxylipin molecule 12,13-dihydroxy-9Z-octadecenoic acid in their blood after a 90 minute session of eccentric exercise than control volunteers. In contrast, they had a 40% lower level of the mildly toxic 9,10-Dihydroxy-12-octadecenoic acid in their blood after exercise than control participants. The authors conclude that daily consumption of almonds changes the metabolism to recover faster after strenuous exercise. For those who exercise regularly, eating almonds each day might be the ideal new year’s resolution. A randomized controlled trial in Frontiers in Nutrition showed that female and male participants who ate 57g almonds daily for one month had more of the beneficial fat 12,13-dihydroxy-9Z-octadecenoic acid (12,13-DiHOME) in their blood immediately after a session of intense exercise than control participants. This molecule, a so-called oxylipin (oxidized fat) is synthetized from linoleic acid by brown fat tissue, and has a beneficial effect on metabolic health and energy regulation. Corresponding author Dr David C Nieman, a professor and director of the Appalachian State University Human Performance Laboratory at the North Carolina Research Campus, said: “Here […]

Health

20 Dec 2022

Lonely heart-failure patients face worse outcomes than sociable peers

by Tania Fitzgeorge-balfour, science writer Social frailty, which includes the loss of social roles, social networks, and social activities, is widely identified as a risk to healthy aging. A new study is the first to show a close association between the loss of perceived social role amongst friends and family and poor clinical outcomes for older heart failure patients. These findings suggest that social engagement and activities should form part of the aftercare program for these patients. Older heart failure patients who feel that they have lost their social role amongst friends and family are more likely to suffer poor clinical outcomes. This is the finding of a new study in Frontiers in Cardiovascular Medicine that has examined the specific aspects of social interaction that can lead to a poor prognosis for these patients. “We are the first to show a close association between the loss of perceived social role and long-term poor clinical outcomes in older heart failure patients,” said Dr Satoshi Katano, first author of this research, based at Sapporo Medical University Hospital, Sapporo, Japan. “Our study highlights the real need to develop a management program that includes a social approach to the care of these patients.” Read […]

Health

13 Dec 2022

The (un)fair allocation of scarce vaccines and how maths can provide a solution

By Prof Carlos Alós-Ferrer Prof Carlos Alós-Ferrer. Image: Nomis Foundation The Covid-19 global vaccine roll-out is considered one of the greatest achievements in modern medical history, saving hundreds of thousands of lives. However, it was marred by decisions that saw those most in need of a vaccine in some countries wait too long, while those perceived to be least at risk getting them first. Now, Prof Carlos Alós-Ferrer of the University of Zurich writes about how he and his colleagues’ latest research in Frontiers in Public Health shows that one maths procedure can ensure a fair distribution of scarce vaccines across the globe. Remember when Covid-19 vaccines first became available? After many months of lockdowns and increasing casualty rates, people across the planet were allowed to exhale a collective sigh of relief. However, as is always the case when new vaccines are developed, there were not enough doses for all who wanted them. Rationing had to be imposed. Unfortunately, the rationing procedures violated elementary ethical principles, which might have led to some elderly and at-risk patients being neglected while younger, healthier citizens were already vaccinated. How did it go wrong? Vaccine acquisition and allocation across the world was as centralized […]

Health

07 Dec 2022

Could new cancer drugs come from potatoes and tomatoes?

by Angharad Brewer Gillham, Frontiers science writer Image/Shutterstock.com Polish scientists revealed the potential for new cancer drugs to be formulated from bioactive compounds found in plants from the genus Solanum, like potatoes and aubergines. Everyone knows someone who has had cancer. In 2020, around 19m new cases — and around 10m deaths — were registered worldwide. Treatments are improving all the time but can damage healthy cells or have severe side-effects which are hard on patients; in the search for new, more targeted cancer drugs, traditional medicine offers many possible candidates. A team of Polish scientists led by Magdalena Winkiel at Adam Mickiewicz University, publishing today in Frontiers in Pharmacology, reviewed the bioactive compounds called glycolalkaloids that are found in many vegetables that are household names, like potatoes and tomatoes, to demonstrate their potential to treat cancer. “Scientists around the world are still searching for the drugs which will be lethal to cancer cells but at the same time safe for healthy cells,” said Winkiel. “It is not easy despite the advances in medicine and powerful development of modern treatment techniques. That is why it might be worth going back to medicinal plants that were used years ago with success […]

Health

05 Dec 2022

Scientists find inorganic food additives might make babies more vulnerable to allergies

By Angharad Brewer Gillham, Frontiers science writer Image/Shutterstock.com Inorganic nanoparticles used to help process food may be crossing the placental barrier and getting into breastmilk, potentially damaging intestinal regulation and compromising babies’ oral tolerance, predisposing them to food allergies. Nanotechnologies have revolutionized food technology with changes to food production, manufacture, and processing that are intended to make our food safer and healthier. Phytosanitary products, processing aids, food additives, and surfaces that touch food in storage can all transfer nanoparticles that might be consumed by humans. In a review published in Frontiers in Allergy today, Mohammad Issa, at the Université Paris-Saclay, and colleagues pointed out that such a significant change to food production could have unforeseen health consequences. The team presented evidence that suggested that nanoparticles not only cross the placenta to reach developing fetuses but leave them at greater risk of potentially life-threatening food allergies. “Due to the immunotoxic and biocidal properties of nanoparticles, exposure may disrupt the host-intestinal microbiota’s beneficial exchanges and may interfere with intestinal barrier and gut-associated immune system development in fetus and neonate,” said Dr Karine Adel-Patient, corresponding author of the study. “This may be linked to the epidemic of immune-related disorders in children, such as […]

Health

30 Nov 2022

Biomarker in urine could be the first to reveal early-stage Alzheimer’s disease

By Conn Hastings, science writer Image: BlurryMe/Shutterstock.com Alzheimer’s disease can remain undetected until it is too late to treat. Large-scale screening programs could help to detect early-stage disease, but current diagnostic methods are too cumbersome and expensive. A new study published to Frontiers is the first to identify formic acid as a sensitive urinary biomarker that can reveal early-stage Alzheimer’s disease, potentially paving the way for inexpensive and convenient disease screening. Could a simple urine test reveal if someone has early-stage Alzheimer’s disease and could this pave the way for large-scale screening programs? A new study in Frontiers in Aging Neuroscience certainly suggests so. The researchers tested a large group of patients with Alzheimer’s disease of different levels of severity and healthy controls with normal cognition to identify differences in urinary biomarkers. They found that urinary formic acid is a sensitive marker of subjective cognitive decline that may indicate the very early stages of Alzheimer’s disease. Current methods to diagnose Alzheimer’s are expensive, inconvenient, and unsuitable for routine screening. This means that most patients only receive a diagnosis when it is too late for effective treatment. However, a non-invasive, inexpensive, and convenient urine test for formic acid could be […]

Health

15 Nov 2022

Balancing blood sugar: article collections on Diabetes

To mark World Diabetes Week, we have gathered our top article collections on Diabetes. With collective views of over 1.1 million, researchers explored topics spanning from stem cell technology for modelling Diabetes and the use of low carbohydrate diets for prevention to integrating digital health technologies in a patient-centered care framework and promising new therapeutic approaches in cardiovascular disease for diabetics. Article collections: Heart health 11 articles | 79,000 views Exploring the intimate relationship between cardiovascular disease and diabetes mellitus, highlighting key opportunities that may lead to promising new therapeutic approaches Alzheimer’s disease 6 articles | 80,000 views More than 35 million patients suffer from dementia, while 380 million battle against diabetes in this aging society. Emerging evidence suggests that diabetes increases the risk of dementia; however, the underlying mechanisms remain to be fully elucidated Patient Care 10 articles | 95,000 views Addressing the challenging and complex issues with Diabetes care, including improving and achieving effective and efficient care at the primary care setting as well as integrating digital health technologies in a patient-centered care framework Nutrition 7 articles | 79,000 views Examining the use of low carbohydrate diets, with or without nutritional ketosis, for the prevention and treatment of […]

Health

30 Sep 2022

‘Love hormone’ revealed to have heart healing properties

By Mischa Dijkstra, Frontiers science writer Image: Shutterstock.com Researchers show for the first time that the neurohormone oxytocin has a previously unsuspected function in both zebrafish and human cell cultures: it stimulates mature cells in the epicardium of the heart to become stem-like cells, which can replace heart cells lost after damage. This discovery could one day be used to stimulate the regeneration of the human heart after a heart attack. The neurohormone oxytocin is well-known for promoting social bonds and generating pleasurable feelings, for example from art, exercise, or sex. But the hormone has many other functions, such as the regulation of lactation and uterine contractions in females, and the regulation of ejaculation, sperm transport, and testosterone production in males. Now, researchers from Michigan State University show that in zebrafish and human tissue cultures, oxytocin has yet another, unsuspected, function: it stimulates stem cells derived from the heart’s outer layer (epicardium), to migrate into its middle layer (myocardium) and there develop into cardiomyocytes, muscle cells that generate heart contractions. This discovery could one day be used to promote the regeneration of the human heart after a heart attack. The results are published in Frontiers in Cell and Developmental Biology. […]

Health

27 Sep 2022

4 articles you need to check out on the future of behavioral neuroscience

By Angharad Brewer Gillham, Frontiers science writer Image: Shutterstock.com How mice and rats help study depression Mice and rats are key model animals that help us understand how depression works and how to treat it. A huge number of people around the world live with this devastating disorder, but its causes and symptoms are so varied that it is hard to test new treatments and to reproduce experiments to prove those treatments work. Scientists writing in Frontiers in Behavioral Neuroscience reviewed the evidence for rodent models of depression and found that models imitating social stress or a disrupted early life have had some success. Meanwhile, models with behavioral stressors designed to induce helplessness are easily compared to other labs’ work but aren’t complex enough to model depression. A key element of depression is anhedonia, struggling to enjoy life, but this is extremely difficult to model in nonhuman animals. The most popular options available test preference for sweet tastes. The team concluded that the best option is to provide mice with a more naturalistic setting to live in, with more space to socialize and to follow their own inclinations. This helps avoid experimenter influence and allows spontaneous behavior from the mice […]

Health

26 Sep 2022

New research shows self-injectable contraception can enable women to take charge of their reproductive health

By Allen Namagembe, PATH, Uganda and Dr Jane Cover, PATH, US Image: PATH/Will Boase Allen Namagembe is a clinical epidemiologist, a biostatistician, and a global expert on self-injection. She is the Uganda Deputy Project Director and M&E Lead on the Uganda Self-Injection Scale-Up project at PATH. Dr. Jane Cover is a Research and Evaluation Manager on PATH’s Sexual and Reproductive Health team and the PATH-JSI DMPA-SC Access Collaborative. Now, they explain their team’s two studies, published in Frontiers in Global Women’s Health, where they used a human-centered design approach to develop and implement a pilot self-injection program in Uganda. Their results show how the program can increase women’s contraceptive access and options. For some, the term ‘self-care’ might conjure up images of skincare routines, bubble baths, and meditation. But in public health, self-care refers to the ability of individuals to self-manage aspects of their health care with the goal of promoting and sustaining health, preventing disease, and managing illness or disability. Grounded in evidence, agency, and equity, self-care interventions are key components of a holistic primary health care system and can help fill gaps in access to essential health services. We both conduct research in the sexual and reproductive health […]

Health

26 Sep 2022

Rodents are reservoirs for life-threatening disease, finds new study

By Tania Fitzgeorge-balfour, science writer Image: Vicky Outen/Shutterstock.com Fungal diseases in the human population are on the rise, so it is important for health authorities to understand where these pathogens come from. A new study has searched for fungi in the lung tissues of small mammals and found fungal pathogens that cause diseases in humans. This suggests that these rodents can serve as reservoirs, agents of dispersal, and incubators of emerging fungal pathogens. Fungal diseases in the human population are on the rise, so it is important for health authorities to understand where these pathogens come from. A new study, published in Frontiers in Fungal Biology, has revealed that small mammals could act as a reservoir for these fungal infections. “Our analysis, which specifically focused on lung pathogens that cause disease in humans, detected a wide range of fungi in the lung tissues of small mammals,” said Paris Salazar-Hamm, first author of this research, of the University of New Mexico. “We found that many of the rodents we sampled from areas in the Southwestern US were harboring the type of fungi that can cause lung infections in humans, such as the fungus that leads to Valley Fever, a disease that […]

Health

23 Sep 2022

Bees, blue light, and bacteria in beetles’ ‘back pockets’: Most viewed articles of August 2022

Image: Shutterstock.com by Angharad Brewer Gillham, Frontiers science writer Each month, Frontiers shines a spotlight on some of the leading research across a wide range of topics. Here are just some of the highlights that resonated strongly with readers on our news site in the month of August. 1. Modern pesticides make it hard for bees to keep on the straight and narrow Research published in Frontiers in Insect Science showed that common pesticides affected bees’ brains so that they couldn’t orient themselves properly. Bees exposed to sulfoxaflor and imidacloprid were tested on their ability to respond to stimuli that tricked them into thinking they’d been blown off course, a situation which required them to use their optomotor response to reorient themselves. Compared to control bees, they performed very poorly, reacting inappropriately or not at all to the stimuli. The problem seems to be caused by damage to the nervous system, but the exact mechanism is unclear. Since bees need this optomotor response to travel between different sources of pollen, and since these insecticides are widely used, this is a source of significant concern. The authors tested the optomotor response in walking bees rather than flying bees, so further research […]

Health

12 Sep 2022

Anti-diarrhea medication may help treat core autism symptoms

By Conn Hastings, science writer Image: Shutterstock.com There are currently no effective treatments for the core symptoms of autism spectrum disorder (ASD), such as difficulties with socializing and communicating. A new study uses a computer-based protein interaction network to identify whether existing drugs could provide a new treatment approach. The researchers discovered that a common anti-diarrheal drug may have potential in treating the social difficulties associated with ASD. Can you teach an old drug new tricks? Although drug treatments for the core symptoms of autism spectrum disorder (ASD) are not currently available, could an existing drug provide a new treatment, even if it previously had no association with ASD? This was the question asked by a new study in the journal Frontiers in Pharmacology. The researchers used a computer model that encompasses proteins involved in ASD and the way they interact. By looking at how different drugs affected proteins in the system, they identified potential candidates to treat it. A commonly used antidiarrheal drug called loperamide was the most promising candidate, and the researchers have an interesting hypothesis about how it may work to treat ASD symptoms. Some of the most common symptoms in ASD involve difficulties with social interaction […]