Cancer remains one of the leading causes of death worldwide, with epidemiological data indicating approximately 10 million cancer-related deaths in 2020. The socio-economic impact of cancer is profound, encompassing not only medical expenses but also non-medical costs such as domestic help, transportation, and special diets. Additionally, the loss of income for patients and their families, along with the financial burden on public health agencies, exacerbates the situation. Despite the adoption of modern therapeutic protocols, significant improvements in prognosis and survival rates for certain cancer types remain elusive. These protocols often come with critical challenges, including the toxicity of chemotherapy drugs, radiotherapy, and complications from surgical treatments. Recently, nanotechnology has emerged as a promising avenue for developing more effective therapeutic strategies. Nanotechnologies offer the potential to overcome existing limitations and stimulate the creation of multifunctional nanoplatforms for tumor targeting, drug loading, and controlled release. However, a comprehensive evaluation of the interactions between nanomaterials and biological systems is still lacking, raising concerns about the potential toxicological effects of engineered nanostructures.
This research topic aims to highlight recent developments in the development and application of Cancer Nanoformulations. The primary objectives include exploring the potential of nanomedicine in anticancer drug delivery, assessing treatment responses, developing cancer vaccines, advancing cancer immunotherapy, and leveraging the unique properties of nanomaterials to enhance therapeutic and imaging modalities. Specific questions to be addressed include the efficacy of nanomaterials in improving tumor targeting and penetration, as well as understanding the toxicological profiles of these materials in biological systems.
To gather further insights into the boundaries of Cancer Nanoformulations, we welcome articles addressing, but not limited to, the following themes:
- Nanomedicine in anticancer drug/nucleotide/protein delivery
- Utilization of nanomedicine for assessment of treatment responses
- Development of cancer vaccines
- Advancement of cancer immunotherapy
- Advantages of nanomaterials in cancer medicine
- Novel therapeutic and imaging modalities offered by nanomaterials
- Enhancing tumor penetration and targeting via nanomaterial solutions
Keywords: Cancer Nanoformulations, Immunotherapy, Tumor Targeting, Toxicology, Nanomedicine
Important note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
