Targeting Adipose Tissue for the Treatment of Metabolic Alterations

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ORIGINAL RESEARCH

Published on 31 Jul 2025

Integrated proteomic and metabolomic profiling identifies distinct molecular signatures and metabolic pathways associated with obesity and potential targets for anti-obesity therapies

Yi Li
Huawu Yang
Xinpeng Zhang
Xingyu He
Anke Liuli
Rui Li
Xingyu Han
Yongmei Li
Pan Gao

doi 10.3389/fendo.2025.1625501

778 views

ORIGINAL RESEARCH

Published on 27 May 2025

Muscle quality index and hyperuricemia: adipose tissue as a mediator

Ya Shao
Yu Wang
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Huiqin Zhong

doi 10.3389/fendo.2025.1562837

1,371 views

ORIGINAL RESEARCH

Published on 14 Apr 2025

Development of an adipocyte differentiation protocol using 3T3-L1 cells for the investigation of the browning process: identification of the PPAR-γ agonist rosiglitazone as a browning reference drug

Lorenzo Flori
Giulia Galgani
Giorgia Bray
Chiara Ippolito
Cristina Segnani
Carolina Pellegrini
Valentina Citi
Nunzia Bernardini
Alma Martelli
Vincenzo Calderone

doi 10.3389/fphar.2025.1546456

2,819 views
1 citation

ORIGINAL RESEARCH

Published on 19 Mar 2025

Sex differences in metabolic regulation by Gi/o-coupled receptor modulation of exocytosis

Montana Young
Ryan P. Ceddia
Analisa Thompson-Gray
David Reyes
Jackson B. Cassada
Julio E. Ayala
Owen P. McGuinness
Sheila Collins
Heidi E. Hamm

doi 10.3389/fphar.2025.1544456

1,425 views

ORIGINAL RESEARCH

Published on 14 Aug 2024

Ling-gui-zhu-gan promotes adipocytes browning via targeting the miR-27b/PRDM16 pathway in 3T3-L1 cells

Zimengwei Ye
Yi Zhao
Yanjing Cui
Bingrui Xu
Fan Wang
Dandan Zhao
Guangtong Dong
Zhufeng Wang
Rui Wu

doi 10.3389/fphar.2024.1386794

1,590 views
1 citation

ORIGINAL RESEARCH

Published on 26 Jun 2024

Identification of ibuprofen targeting CXCR family members to alleviate metabolic disturbance in lipodystrophy based on bioinformatics and in vivo experimental verification

Zhiwen Cao
Yuxiao Zhao
Ruixin Liu
Xialin Yan
Jiqiu Wang
Na Chen

doi 10.3389/fendo.2024.1414908

1,640 views
1 citation

ORIGINAL RESEARCH

Published on 21 Mar 2024

Xiasangju alleviate metabolic syndrome by enhancing noradrenaline biosynthesis and activating brown adipose tissue

Changhao He
Yongcheng An
Lu Shi
Yan Huang
Huilin Zhang
Wanxin Fu
Menglu Wang
Ziyi Shan
Yuhang Du
4 more
Baosheng Zhao

doi 10.3389/fphar.2024.1371929

1,971 views
7 citations

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Translational Pharmacology

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Frontiers in Endocrinology
- Obesity
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Articles

Integrated proteomic and metabolomic profiling identifies distinct molecular signatures and metabolic pathways associated with obesity and potential targets for anti-obesity therapies

Muscle quality index and hyperuricemia: adipose tissue as a mediator

Development of an adipocyte differentiation protocol using 3T3-L1 cells for the investigation of the browning process: identification of the PPAR-γ agonist rosiglitazone as a browning reference drug

Sex differences in metabolic regulation by Gi/o-coupled receptor modulation of exocytosis

Ling-gui-zhu-gan promotes adipocytes browning via targeting the miR-27b/PRDM16 pathway in 3T3-L1 cells

Identification of ibuprofen targeting CXCR family members to alleviate metabolic disturbance in lipodystrophy based on bioinformatics and in vivo experimental verification

Xiasangju alleviate metabolic syndrome by enhancing noradrenaline biosynthesis and activating brown adipose tissue

Frontiers in Pharmacology

Translational Pharmacology

Participating Journals

Frontiers in Endocrinology

Obesity