Cancer causes 1 in every 6 deaths worldwide, and the burden of cancer is rising in nearly every country. The number of new cancer cases per annum is expected to rise by approximately 50% come 2040 (from 19.3 M to 30.2 M cases/year from 2020-2040), and the number of annual cancer deaths is projected to increase by more than 60% (from 9.96 M to 15.3 M deaths/year from 2020-2040). However, the WHO estimates that between 30-50% of cancer cases are preventable through proper nutrition and a healthy lifestyle. This includes eating a diet rich in fruits and vegetables, maintaining a healthy body weight, getting regular physical activity, and avoiding exposure to carcinogens. In addition, research has identified key nutrients (e.g., vitamin C, D, selenium, folic acid, carotenoids, etc.) that may exert anticancer effects through various mechanisms such as reducing oxidative stress and induction of cancer cell apoptosis. Further research is needed to harness the full potential of these nutrients when it comes to individualized prevention.
This research topic aims to draw attention to the importance of nutrition and lifestyle in cancer prevention by showcasing the latest molecular and cellular research in these fields. Despite the large influence of nutrition and lifestyle on the development of cancer, both healthcare professionals and the general population underutilize these approaches. Furthermore, research on nutrition and lifestyle appears to be largely underrepresented in published cancer research. The limited number of studies contributes to a lack of knowledge and consensus among major cancer research organizations about the possible anticancer effects of certain nutrients and lifestyle habits in the context of specific cancer types, population subsets, and at-risk individuals. This research topic hopes to draw awareness to this issue by highlighting the most recent nutrition and lifestyle-centered cancer research. In the long-term, more research in this area will hopefully contribute to greater use of nutrition and lifestyle to prevent cancer development.
This research topic is open to a broad range of original research, reviews, systematic reviews, and mini-reviews centered around the effects of nutrition and lifestyle on cancer prevention and progression. We are especially interested in research articles exploring the following areas:
- Studies on specific nutrients, foods, diets, or lifestyle habits that may increase or decrease the risk of cancer, emphasizing cellular and/or molecular mechanisms.
- Effects of specific nutrients on cancer cell growth in vitro and/or in vivo.
- Effects of specific nutrients or lifestyle habits on biomarkers of cancer risk (e.g., oxidative stress, DNA damage, PSA levels, etc.).
- Bioactive compounds of food (including phytochemicals) and their prevention of oncogenesis.
- Nutrition and the human microbiota in cancer development.
- Micronutrient (vitamins and minerals) intake influences cancer prevention and progression.
Please note the following conflict of interest disclosures for Dr. Kenneth W. Yip:
- Patent No. 11,819,535. Liu FF, Zhao, X, Yip KW. Composition and methods for regulating extracellular matrix accumulation. Issued Nov. 21, 2023 (no revenues generated).
- co-founder of XMK Therapeutics (no financial support).
- co-founder and Scientific Lead of Anticancer.ca (no financial support).
Dr. Maicon Roberto Kviecinski and Dr. Fabiana Ourique declared no conflict of interest.
Keywords:
nutrition, cancer prevention, cancer, natural products, nutrients, Lifestyle
Important Note:
All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
Cancer causes 1 in every 6 deaths worldwide, and the burden of cancer is rising in nearly every country. The number of new cancer cases per annum is expected to rise by approximately 50% come 2040 (from 19.3 M to 30.2 M cases/year from 2020-2040), and the number of annual cancer deaths is projected to increase by more than 60% (from 9.96 M to 15.3 M deaths/year from 2020-2040). However, the WHO estimates that between 30-50% of cancer cases are preventable through proper nutrition and a healthy lifestyle. This includes eating a diet rich in fruits and vegetables, maintaining a healthy body weight, getting regular physical activity, and avoiding exposure to carcinogens. In addition, research has identified key nutrients (e.g., vitamin C, D, selenium, folic acid, carotenoids, etc.) that may exert anticancer effects through various mechanisms such as reducing oxidative stress and induction of cancer cell apoptosis. Further research is needed to harness the full potential of these nutrients when it comes to individualized prevention.
This research topic aims to draw attention to the importance of nutrition and lifestyle in cancer prevention by showcasing the latest molecular and cellular research in these fields. Despite the large influence of nutrition and lifestyle on the development of cancer, both healthcare professionals and the general population underutilize these approaches. Furthermore, research on nutrition and lifestyle appears to be largely underrepresented in published cancer research. The limited number of studies contributes to a lack of knowledge and consensus among major cancer research organizations about the possible anticancer effects of certain nutrients and lifestyle habits in the context of specific cancer types, population subsets, and at-risk individuals. This research topic hopes to draw awareness to this issue by highlighting the most recent nutrition and lifestyle-centered cancer research. In the long-term, more research in this area will hopefully contribute to greater use of nutrition and lifestyle to prevent cancer development.
This research topic is open to a broad range of original research, reviews, systematic reviews, and mini-reviews centered around the effects of nutrition and lifestyle on cancer prevention and progression. We are especially interested in research articles exploring the following areas:
- Studies on specific nutrients, foods, diets, or lifestyle habits that may increase or decrease the risk of cancer, emphasizing cellular and/or molecular mechanisms.
- Effects of specific nutrients on cancer cell growth in vitro and/or in vivo.
- Effects of specific nutrients or lifestyle habits on biomarkers of cancer risk (e.g., oxidative stress, DNA damage, PSA levels, etc.).
- Bioactive compounds of food (including phytochemicals) and their prevention of oncogenesis.
- Nutrition and the human microbiota in cancer development.
- Micronutrient (vitamins and minerals) intake influences cancer prevention and progression.
Please note the following conflict of interest disclosures for Dr. Kenneth W. Yip:
- Patent No. 11,819,535. Liu FF, Zhao, X, Yip KW. Composition and methods for regulating extracellular matrix accumulation. Issued Nov. 21, 2023 (no revenues generated).
- co-founder of XMK Therapeutics (no financial support).
- co-founder and Scientific Lead of Anticancer.ca (no financial support).
Dr. Maicon Roberto Kviecinski and Dr. Fabiana Ourique declared no conflict of interest.
Keywords:
nutrition, cancer prevention, cancer, natural products, nutrients, Lifestyle
Important Note:
All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.