BRIEF RESEARCH REPORT
Accepted on 20 Oct 2025
Towards new approach methodologies for biological therapeutics: A novel model-informed metric to assess immunogenicity risk
doi 10.3389/fimmu.2025.1677925
- Frontiers in Immunology
- Vaccines and Molecular Therapeutics
- Research Topics
- Advances in Immunogenicity Risk Assessment, Monitoring and Mitigation of Biologics
Advances in Immunogenicity Risk Assessment, Monitoring and Mitigation of Biologics
6,434
Total downloads
33k
Total views and downloads
Submit your idea
You will be redirected to our submission process.
Articles
ORIGINAL RESEARCH
Published on 12 Sep 2025
A real-time imaging approach to quantify dendritic cell internalization for immunogenicity risk assessment of biotherapeutics
doi 10.3389/fimmu.2025.1632302
- 4,099 views
REVIEW
Published on 05 Sep 2025
Antigen-presenting cell internalization is key for understanding and evaluating therapeutic antibodies’ immunogenicity
doi 10.3389/fimmu.2025.1617395
- 1,592 views
ORIGINAL RESEARCH
Published on 04 Jul 2025
The TNFα-binding domain of the therapeutic antibody adalimumab elicits CD4 T-cell responses in rheumatoid arthritis patients
doi 10.3389/fimmu.2025.1549781
- 1,887 views
PERSPECTIVE
Published on 18 Jun 2025
Immunogenicity of therapeutic peptide products: bridging the gaps regarding the role of product-related risk factors
doi 10.3389/fimmu.2025.1608401
- 2,572 views
- 3 citations
SYSTEMATIC REVIEW
Published on 22 May 2025
Immunogenicity risk assessment for tailored mitigation and monitoring of biotherapeutics during development: recommendations from the European Immunogenicity Platform
doi 10.3389/fimmu.2025.1581153
- 6,929 views
- 5 citations
ORIGINAL RESEARCH
Published on 20 Mar 2025
The first WHO reference panel for Infliximab anti-drug antibodies: a step towards harmonizing therapeutic drug monitoring
doi 10.3389/fimmu.2025.1550655
- 1,830 views
- 2 citations
ORIGINAL RESEARCH
Published on 27 Feb 2025
Antidrug antibodies to adalimumab do not associate with immunologically related adverse events
doi 10.3389/fimmu.2024.1457993
- 2,789 views
- 1 citation
ORIGINAL RESEARCH
Published on 13 Feb 2025
A single point mutation on FLT3L-Fc protein increases the risk of immunogenicity
doi 10.3389/fimmu.2025.1519452
- 2,628 views
- 2 citations
ORIGINAL RESEARCH
Published on 10 Dec 2024
Immune regulatory adjuvant approach to mitigate subcutaneous immunogenicity of monoclonal antibodies
doi 10.3389/fimmu.2024.1496169
- 2,512 views
- 2 citations
Manuscripts can be submitted to this Research Topic via the main journal or any other participating journal.
Submit your idea
You will be redirected to our submission process.