Prevention and Treatment of Metabolic Diseases Using Bioactive Metabolites of Herbal Medicines Also Used as Foods

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ORIGINAL RESEARCH

Published on 06 Jun 2025

Hydroxysafflor yellow A alleviates oxidative stress and inflammatory damage in the livers of mice with nonalcoholic fatty liver disease and modulates gut microbiota

Liang Wu
Xueyun Dong
Wen Sun
Tan Jiajun
Asmaa Ali
Jiayuan He
Pingping Wang

doi 10.3389/fphar.2025.1568608

1,265 views

ORIGINAL RESEARCH

Published on 30 May 2025

Transcriptomic and metabonomic profiling unveils the mechanism of Tartary buckwheat and kiwi co-fermentation products in hyperlipidemia treatment

Nan Guohui
Xie Tingna
He Qinghui
Yu Hongchun
Peng Jing
Jiang Shiyin
Li Li
Yuan Huawei
Wei Daijing
Wu Qi

doi 10.3389/fphar.2025.1572593

664 views

ORIGINAL RESEARCH

Published on 25 Apr 2025

Therapeutic effects of medicinal and food-based traditional herbal couples on type 2 diabetes mellitus based on pharmacodynamics and pharmacokinetics

Yuhang Xu
Jing Li
Mengyao Cui
Xiaoliang Li
Hongyan Zhai
Deling Wu
Xiaoqin Chu

doi 10.3389/fphar.2025.1560271

1,346 views

ORIGINAL RESEARCH

Published on 22 Apr 2025

Delites™ supplementation prevents metabolic syndrome onset and modulates gut microbiome in male Sprague Dawley rats fed on cholesterol- and fat-enriched diet: a randomized preclinical trial study

Juan Leonardo
Robby Hertanto
Reggie Surya
Rony Abdi Syahputra
Wardina Humayrah
Nindy Sabrina
Nurpudji Astuti Taslim
Trina Ekawati Tallei
Raymond Rubianto Tjandrawinata
Fahrul Nurkolis

doi 10.3389/fnut.2025.1571473

1,269 views

ORIGINAL RESEARCH

Published on 09 Apr 2025

Targeted metabolomics unravels the mechanism by phenylpropanoid-rich of the peel of Zea mays L. ameliorates metabolic disorders in diabetic mice through gut microbiota modulation

Xiaotian Cheng
Jinyan He
Yuru Yang
Yaonan He
Guangtong Chen
Bai Ling
Andong Wang

doi 10.3389/fphar.2025.1551713

838 views

ORIGINAL RESEARCH

Published on 31 Mar 2025

The methodological reporting quality in strictly randomized controlled trials for COVID-19 and precise reporting of Chinese herbal medicine formula intervention

Min-Li Chen
Shi-Yan Qian
Jiang-Li Yang
Jue-Yan Zheng
Li-Xiang Wang
Jing-Ying Wu
Hai-Qin Ye
Yan Wang
Guo-Qing Zheng

doi 10.3389/fphar.2025.1532290

1,042 views

ORIGINAL RESEARCH

Published on 20 Feb 2025

Thonningianin A ameliorates acetaminophen-induced liver injury by activating GPX4 and modulating endoplasmic reticulum stress

Shanglei Lai
Yingyan Ye
Qinchao Ding
Xiaokai Hu
Ai Fu
Lan Wu
Wenjing Cao
Qingsheng Liu
Xiaobing Dou
Xuchen Qi

doi 10.3389/fphar.2025.1531277

1,386 views

ORIGINAL RESEARCH

Published on 13 Feb 2025

Network analysis and experimental validation to investigate chenpi against functional dyspepsia through TLR4/MyD88 by regulating the gut microbial structure

Jinfang Hu
Xu Wang
Xiaoqiu Guo
Wen Wen
Jin Xue
Zhengzheng Liao
Lihua Chen

doi 10.3389/fphar.2025.1495799

962 views

REVIEW

Published on 11 Feb 2025

Natural compounds in the management of polycystic ovary syndrome: a comprehensive review of hormonal regulation and therapeutic potential

Jingyi Yuan
Zhenmin Li
Yongjiang Yu
Xiuge Wang
Yunyun Zhao

doi 10.3389/fnut.2025.1520695

4,517 views
4 citations

ORIGINAL RESEARCH

Published on 07 Jan 2025

Portulaca oleracea L. (purslane) extract ameliorates intestinal inflammation in diet-induced obese mice by inhibiting the TLR4/NF-κB signaling pathway

Lingchao Miao
Meng Sam Cheong
Haolin Zhang
Haroon Khan
Hongxun Tao
Yuxiao Wang
Wai San Cheang

doi 10.3389/fphar.2024.1474989

981 views

ERRATUM

Published on 19 Dec 2024

Erratum: Triterpenoids from Ganoderma lucidum inhibit cytochrome P450 enzymes interfering with the metabolic process of specific clinical drugs

Frontiers Production Office

doi 10.3389/fphar.2024.1539089

291 views

ORIGINAL RESEARCH

Published on 15 Nov 2024

Triterpenoids from Ganoderma lucidum inhibit cytochrome P450 enzymes interfering with the metabolic process of specific clinical drugs

Dawei Li
Yuxin Lin
Xia Lv
Yuzhuo Wu
Chaoyan Han
Peng Cao
Guixin Zhang
Aijing Leng
Jian Zhou
Chao Wang

doi 10.3389/fphar.2024.1485209

1,369 views

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Articles

Hydroxysafflor yellow A alleviates oxidative stress and inflammatory damage in the livers of mice with nonalcoholic fatty liver disease and modulates gut microbiota

Transcriptomic and metabonomic profiling unveils the mechanism of Tartary buckwheat and kiwi co-fermentation products in hyperlipidemia treatment

Therapeutic effects of medicinal and food-based traditional herbal couples on type 2 diabetes mellitus based on pharmacodynamics and pharmacokinetics

Delites™ supplementation prevents metabolic syndrome onset and modulates gut microbiome in male Sprague Dawley rats fed on cholesterol- and fat-enriched diet: a randomized preclinical trial study

Targeted metabolomics unravels the mechanism by phenylpropanoid-rich of the peel of Zea mays L. ameliorates metabolic disorders in diabetic mice through gut microbiota modulation

The methodological reporting quality in strictly randomized controlled trials for COVID-19 and precise reporting of Chinese herbal medicine formula intervention

Thonningianin A ameliorates acetaminophen-induced liver injury by activating GPX4 and modulating endoplasmic reticulum stress

Network analysis and experimental validation to investigate chenpi against functional dyspepsia through TLR4/MyD88 by regulating the gut microbial structure

Natural compounds in the management of polycystic ovary syndrome: a comprehensive review of hormonal regulation and therapeutic potential

Portulaca oleracea L. (purslane) extract ameliorates intestinal inflammation in diet-induced obese mice by inhibiting the TLR4/NF-κB signaling pathway

Erratum: Triterpenoids from Ganoderma lucidum inhibit cytochrome P450 enzymes interfering with the metabolic process of specific clinical drugs

Triterpenoids from Ganoderma lucidum inhibit cytochrome P450 enzymes interfering with the metabolic process of specific clinical drugs

Frontiers in Pharmacology

Ethnopharmacology

Participating Journals

Frontiers in Nutrition

Nutrition and Metabolism