Innovations in Pharmacogenomics: Embracing Diversity and Clinical Application

3,579
Total downloads
21k
Total views and downloads

Articles

SYSTEMATIC REVIEW

Accepted on 15 Oct 2025

Impact of CYP2C19 point-of-care testing on the clinical outcome in patients receiving personalized clopidogrel therapy: Systemic review and meta-analysis

Shaban Mohammed
Zainab Ali
Nermin Mohammed
Ayman El-Menyar
Jassim M Al Suwaidi
Moza Al Hail
Wadha Al Muftah
Rania Abdel-latif
Maw Shin Sim

doi 10.3389/fphar.2025.1621327

195 views

SYSTEMATIC REVIEW

Published on 24 Sep 2025

Pharmacogenetics of metamizole-induced agranulocytosis: a systematic review and drug regulation implications

Giovana Fernanda Santos Fidelis
Carolina Dagli-Hernandez
Romina P. Martinelli
Jefman Efendi Marzuki
Baharuddin Baharuddin
Qun-Ying Yue
Brian Edwards
Eder de Carvalho Pincinato
Patricia Moriel

doi 10.3389/fphar.2025.1624044

1,244 views

ORIGINAL RESEARCH

Published on 19 Sep 2025

Prevalence of risk phenotypes associated with CYP2C92, 3, and VKORC1 c.-1639G>A genetic polymorphisms in world populations: implications in clinical practice

Mohitosh Biswas
Murshadul Alam Murad
Maliheh Ershadian
Most. Sumaiya Khatun Kali
Maw Shin Sim
Baharudin Ibrahim
Chonlaphat Sukasem

doi 10.3389/fphar.2025.1597379

1,117 views
1 citation

ORIGINAL RESEARCH

Published on 29 Aug 2025

A multi-centre observational cohort study on pharmacogenomic predictors of rosuvastatin discontinuation in a multiethnic population

Mais N. Alqasrawi
Zeina N. Al-Mahayri
Lubna Q. Khasawneh
Areej S. AlBawa’neh
Lilas Dabaghie
Sahar M. Altoum
Dana Hamza
Salahdein Aburuz
Virendra Misra
8 more
Bassam R. Ali

doi 10.3389/fphar.2025.1656520

1,479 views

ORIGINAL RESEARCH

Published on 29 Aug 2025

Pharmacogenomics and genetic ancestry in Colombia: a study on all variant drug annotations of PharmGKB

Andy A. Acosta-Monterrosa
Kevin Fernando Montoya-Quintero
Johana Galván-Barrios
Indiana Luz Rojas Torres

doi 10.3389/fphar.2025.1636451

1,247 views

SYSTEMATIC REVIEW

Published on 16 Jul 2025

Polymorphisms in CYP3A5, CYP3A4, and ABCB1 genes: implications for calcineurin inhibitors therapy in hematopoietic cell transplantation recipients—a systematic review

Luiz Carlos da Costa-Junior
Daniely Regina Freitas-Alves
Amanda Melo Leite Leão
Hayra de Andrade Vieira Monteiro
Rita de Cássia Barbosa da Silva Tavares
Maria Claudia Rodrigues Moreira
Marília Berlofa Visacri
Teresa de Souza Fernandez
Paulo Caleb Júnior de Lima Santos

doi 10.3389/fphar.2025.1569353

1,580 views

ORIGINAL RESEARCH

Published on 29 May 2025

Clinical impact of pharmacogenomics in pediatric care: insights extracted from clinical exome sequencing

Simran Maggo
Yachen Pan
Dejerianne Ostrow
Jenny Q. Nguyen
Jaclyn A. Biegel
Matthew A. Deardorff
Xiaowu Gai

doi 10.3389/fgene.2025.1574325

2,170 views

BRIEF RESEARCH REPORT

Published on 22 May 2025

Implementation and integration of a multidisciplinary pharmacogenomics service in an underserved integrated behavioral health clinic

Bader M. Alghamdi
Sara Rogers
Susan Roberman
Meredith Williamson
Ladan Panahi

doi 10.3389/fphar.2025.1594032

1,593 views

ORIGINAL RESEARCH

Published on 28 Apr 2025

Genetic polymorphisms in SLC5A2 are associated with clinical outcomes and dapagliflozin response in heart failure patients

Ahmed Essam Abou Warda
Rylie M. Flohr
Rania M. Sarhan
Mohamed Nabil Salem
Heba F. Salem
Ayman N. Moharram
Abdullah S. Alanazi
Christelle Lteif
Brian E. Gawronski
5 more
Julio D. Duarte

doi 10.3389/fphar.2025.1539870

2,551 views
2 citations

REVIEW

Published on 28 Apr 2025

Research progress on m6A and drug resistance in gastrointestinal tumors

Ziyi Xu
Bo Sun
Weizheng Wang
Yitao Fan
Jingxiang Su
Jiachun Sun
Xinyu Gu

doi 10.3389/fphar.2025.1565738

1,556 views

MINI REVIEW

Published on 12 Feb 2025

Association between CYP2C19 polymorphism and proton pump inhibitors adverse drug reactions: a narrative review

Asmaa Ibrahim
Kazeem Yusuff
Ahmed Awaisu
Hazem Elewa

doi 10.3389/fphar.2025.1523399

2,174 views
1 citation

Share on

Frontiers in Pharmacology

Pharmacogenetics and Pharmacogenomics

Participating Journals

Frontiers in Genetics
- Pharmacogenetics and Pharmacogenomics
- 2.8 impact factor
- 6.2 citescore

Impact

21kTopic views
16kArticle views
3,579Article downloads

View impact

Articles

Impact of CYP2C19 point-of-care testing on the clinical outcome in patients receiving personalized clopidogrel therapy: Systemic review and meta-analysis

Pharmacogenetics of metamizole-induced agranulocytosis: a systematic review and drug regulation implications

Prevalence of risk phenotypes associated with CYP2C9*2, *3, and VKORC1 c.-1639G>A genetic polymorphisms in world populations: implications in clinical practice

A multi-centre observational cohort study on pharmacogenomic predictors of rosuvastatin discontinuation in a multiethnic population

Pharmacogenomics and genetic ancestry in Colombia: a study on all variant drug annotations of PharmGKB

Polymorphisms in CYP3A5, CYP3A4, and ABCB1 genes: implications for calcineurin inhibitors therapy in hematopoietic cell transplantation recipients—a systematic review

Clinical impact of pharmacogenomics in pediatric care: insights extracted from clinical exome sequencing

Implementation and integration of a multidisciplinary pharmacogenomics service in an underserved integrated behavioral health clinic

Genetic polymorphisms in SLC5A2 are associated with clinical outcomes and dapagliflozin response in heart failure patients

Research progress on m6A and drug resistance in gastrointestinal tumors

Association between CYP2C19 polymorphism and proton pump inhibitors adverse drug reactions: a narrative review

Frontiers in Pharmacology

Pharmacogenetics and Pharmacogenomics

Participating Journals

Frontiers in Genetics

Pharmacogenetics and Pharmacogenomics

Prevalence of risk phenotypes associated with CYP2C92, 3, and VKORC1 c.-1639G>A genetic polymorphisms in world populations: implications in clinical practice