Development and Validation of New Molecular Probes of Nuclear Medicine and New Targets of Nuclear Drugs in Cancers

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ORIGINAL RESEARCH

Accepted on 20 Oct 2025

Experimental Study on the Treatment of Norepinephrine Transporter-Overexpressing Pheochromocytomas and paragangliomas: A Synthetic Lethality Strategy Combining 131I-MIBG with PARP Inhibitors

JiePing Song
Lulu zhang
Fan Qiu
Xiumin Shi
Rui Tian
Chuan Zhang
Xiaoyuan Li
Feng Wang

doi 10.3389/fonc.2025.1681054

ORIGINAL RESEARCH

Published on 25 Sep 2025

Clozapine is responsible for the in vivo imaging and pharmacological effects of clozapine-N-oxide in murine DREADD models

Jian Wang
Jiale Qin
Katsushi Kumata
Ming-Rong Zhang
Jun Qian
Wen Zhou
Bin Ji

doi 10.3389/fphar.2025.1671065

801 views

ORIGINAL RESEARCH

Published on 28 Aug 2025

Role of 18F-AlF-NOTATATE PET/CT in selecting pediatric neuroblastoma candidates for 177Lu-DOTATATE peptide receptor radionuclide therapy

Yuxuan Liu
Yingying Sun
Di Zuo
Han Wang
Fei Zheng
Jingfu Wang
Xiaorong Sun

doi 10.3389/fmed.2025.1615136

2,923 views

ORIGINAL RESEARCH

Published on 03 Jul 2025

The value of 18F-AlF-NOTATATE PET/CT in restaging high-risk neuroblastoma after chemotherapy

Han Wang
Di Zuo
Fei Zheng
Yingying Sun
Yuxuan Liu
Hao Yang
Jingfu Wang
Xiaorong Sun

doi 10.3389/fmed.2025.1596272

1,575 views

ORIGINAL RESEARCH

Published on 04 Jun 2025

SPAG6 Promotes Multiple Myeloma Through Activation of the MAPK/ERK Signaling Pathway

Junnan Li
Xinyu Yan
Li Ding
Jiaxiu Yin
Ping Li
Lin Liu

doi 10.3389/fphar.2025.1572621

1,137 views
1 citation

ORIGINAL RESEARCH

Published on 15 May 2025

Preclinical studies of a PARP-targeted theranostic radiopharmaceutical for pancreatic cancer

Jie Gao
Yuhao Wang
Ruoqi Wang
Mengya Liu
Hongliang Wang
Jianguo Li
Jin Du

doi 10.3389/fphar.2025.1576587

1,377 views
1 citation

REVIEW

Published on 14 May 2025

Based on small molecules: development and application of fibroblast activation protein inhibitors radiopharmaceutical in tumor precision therapy

Yihui Luo
Haitian Fu
Chunjing Yu

doi 10.3389/fphar.2025.1593380

3,392 views

REVIEW

Published on 08 May 2025

Cuproptosis-related genes and agents: implications in tumor drug resistance and future perspectives

Lingwen Xu
Xiaolan Cao
Yuxiao Deng
Bin Zhang
Xinzhi Li
Wentao Liu
Wenjie Ren
Xuan Tang
Xiangyu Kong
Daizhou Zhang

doi 10.3389/fphar.2025.1559236

2,819 views

ORIGINAL RESEARCH

Published on 10 Apr 2025

Predictive significance of 18F-FDG PET/CT metabolic parameters for the expression level of HER2 in gastric cancer

Zhang Shilai
Mo Shaozhou
Wei Linlin
Chai Hua
Pu Weiwei
Liu Ziya
Qiu Wenming
Yang Zhi
Liao Hai
Xiao Guoyou

doi 10.3389/fonc.2025.1580166

1,136 views

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Frontiers in Oncology

Pharmacology of Anti-Cancer Drugs

Participating Journals

Frontiers in Medicine
- Nuclear Medicine
- 3.0 impact factor
- 6.0 citescore
Frontiers in Pharmacology
- Pharmacology of Anti-Cancer Drugs
- 4.8 impact factor
- 8.9 citescore

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18kTopic views
14kArticle views
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Articles

Experimental Study on the Treatment of Norepinephrine Transporter-Overexpressing Pheochromocytomas and paragangliomas: A Synthetic Lethality Strategy Combining 131I-MIBG with PARP Inhibitors

Clozapine is responsible for the in vivo imaging and pharmacological effects of clozapine-N-oxide in murine DREADD models

Role of 18F-AlF-NOTATATE PET/CT in selecting pediatric neuroblastoma candidates for 177Lu-DOTATATE peptide receptor radionuclide therapy

The value of 18F-AlF-NOTATATE PET/CT in restaging high-risk neuroblastoma after chemotherapy

SPAG6 Promotes Multiple Myeloma Through Activation of the MAPK/ERK Signaling Pathway

Preclinical studies of a PARP-targeted theranostic radiopharmaceutical for pancreatic cancer

Based on small molecules: development and application of fibroblast activation protein inhibitors radiopharmaceutical in tumor precision therapy

Cuproptosis-related genes and agents: implications in tumor drug resistance and future perspectives

Predictive significance of 18F-FDG PET/CT metabolic parameters for the expression level of HER2 in gastric cancer

Frontiers in Oncology

Pharmacology of Anti-Cancer Drugs

Participating Journals

Frontiers in Medicine

Nuclear Medicine

Frontiers in Pharmacology

Pharmacology of Anti-Cancer Drugs