Innovative Approaches in Pulmonary Hypertension Prevention and Treatment Using Natural Compounds

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ORIGINAL RESEARCH

Published on 15 Apr 2026

Baicalin-geniposide attenuates pulmonary inflammation and vascular injury via HMGB1 blockade: insights from a cerebral ischemia-reperfusion model and implications for pulmonary hypertension

Leying Gao
Qianqian Wu
Xiaoqiu Li
Yu Long
Nan Li

doi 10.3389/fphar.2026.1822890

REVIEW

Published on 05 Mar 2026

Multifaceted mechanisms of plant metabolites in pulmonary arterial hypertension: a critical review beyond vasodilation

Junjun Li
Chenyan Hu
Jia-Hui Zhu
Ruo-Lan Li

doi 10.3389/fphar.2026.1769990

178 views

REVIEW

Published on 26 Jan 2026

Pulmonary hypertension: etiology and anti-inflammatory treatment pathways of natural products

Liyang Li
Xing Huang
Maojun Cheng
Chengxun He
Changmao Dai
Fang Ding
Jia Xu
Feier Chen
Kaichen Zhang
Xueping Li

doi 10.3389/fphar.2025.1743782

820 views

REVIEW

Published on 22 Jan 2026

Natural terpenoids with therapeutic potential against pulmonary arterial hypertension

Kaijie Dang
Junru Zhang
Kexin Yu
Xinyu Liu
Yi Zhu
Xiuli Yang
Xiao Liu
Chuantao Zhang

doi 10.3389/fphar.2025.1713745

913 views

REVIEW

Published on 12 Jan 2026

Acute high-altitude illness: risk factors, susceptibility prediction, and personalized prevention and treatment

Nan Jia
Chen Chen
Qian Chen
Junling Liu
Zherui Shen
Yuhan Liu
Caixia Pei
Yilan Wang
Demei Huang
2 more
Zhenxing Wang

doi 10.3389/fmed.2025.1735083

1,391 views

REVIEW

Published on 08 Jan 2026

Natural products targeting the immune-metabolic regulatory network in pulmonary hypertension: mechanisms, classification, and therapeutic prospects

Jianli Ma
Xiyu Cao
Xiuli Yang
Yi Zhu
Hualing Wang
Yundou Liu
Ke Chen
Xiao Liu
Chuantao Zhang

doi 10.3389/fphar.2025.1712903

1,322 views

BRIEF RESEARCH REPORT

Published on 18 Nov 2025

Correlation between anticoagulant initiation time and thrombolysis at 30 days after anticoagulation therapy in patients with pulmonary embolism

Yaojie Zhou
Danrong Yang
Yi Liu

doi 10.3389/fmed.2025.1690899

943 views

ORIGINAL RESEARCH

Published on 22 Jul 2025

Pharmacological targeting of ferroptosis in hypoxia-induced pulmonary edema: therapeutic potential of ginsenoside Rg3 through activation of the PI3K/AKT pathway

Yacong He
Yilang Wang
Huxinyue Duan
Demei Huang
Nan Jia
Zherui Shen
Zhenxing Wang
Mingjie Wang
Tianzhu Zhao

doi 10.3389/fphar.2025.1644436

2,500 views
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Frontiers in Pharmacology

Ethnopharmacology

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Frontiers in Medicine
- Pulmonary Medicine
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Articles

Baicalin-geniposide attenuates pulmonary inflammation and vascular injury via HMGB1 blockade: insights from a cerebral ischemia-reperfusion model and implications for pulmonary hypertension

Multifaceted mechanisms of plant metabolites in pulmonary arterial hypertension: a critical review beyond vasodilation

Pulmonary hypertension: etiology and anti-inflammatory treatment pathways of natural products

Natural terpenoids with therapeutic potential against pulmonary arterial hypertension

Acute high-altitude illness: risk factors, susceptibility prediction, and personalized prevention and treatment

Natural products targeting the immune-metabolic regulatory network in pulmonary hypertension: mechanisms, classification, and therapeutic prospects

Correlation between anticoagulant initiation time and thrombolysis at 30 days after anticoagulation therapy in patients with pulmonary embolism

Pharmacological targeting of ferroptosis in hypoxia-induced pulmonary edema: therapeutic potential of ginsenoside Rg3 through activation of the PI3K/AKT pathway

Frontiers in Pharmacology

Ethnopharmacology

Other participating journals

Frontiers in Medicine

Pulmonary Medicine