Precision Immuno-Oncology: Harnessing Novel Drug Development, Biomarkers, and Nanoparticle-Based Therapeutic Platforms to Overcome Cancer Resistance

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STUDY PROTOCOL

Accepted on 22 Dec 2025

TROPION-Lung10: a phase 3 study of datopotamab deruxtecan and rilvegostomig in patients with treatment-naïve locally advanced or metastatic nonsquamous non-small cell lung cancer with high PD-L1 expression and without actionable genomic alterations

Tom Newsom-Davis
Barbara Melosky
Rebecca S Heist
Shun Lu
Giulia Pasello
Xiwei Chen
Marta Stachowiak
Pavlo Lyfar
Alessandra Forcina
Suresh S Ramalingam

208 views

MINI REVIEW

Published on 15 Dec 2025

Nanovaccines in gastrointestinal cancers

YuHan Wang
Peng Huang
Chun Li
ShengJin Tu
Hua Yang

doi 10.3389/fimmu.2025.1680053

639 views

CLINICAL TRIAL

Published on 03 Dec 2025

Combination immunotherapy and anti-angiogenic therapy shows promising efficacy in NSCLC patients with recurrent or refractory brain metastases and negative driver genes

Liwei Sun
Bonian Chen
Bin Wang
Jinduo Li
Lin Li
Caijuan Tian
Hongbo Zhang
Pengfei Liu
Xiaomin Liu

doi 10.3389/fimmu.2025.1684759

1,290 views

REVIEW

Published on 20 Nov 2025

Targeting cancer via macrophage-derived exosomal miRNAs: implications for tumor progression and resistance

Prasanna Srinivasan Ramalingam
Muhammad Afzal
M. Arockia Babu
Rekha M. M.
Samir Sahoo
Surya Nath Pandey
Haider Ali
Md Sadique Hussain
Gaurav Gupta
1 more
Sivakumar Arumugam

doi 10.3389/fimmu.2025.1683799

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Frontiers in Immunology

Cancer Immunity and Immunotherapy

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Frontiers in Oncology
- Cancer Immunity and Immunotherapy
- 3.3 impact factor
- 6.9 citescore

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