Novel Immune Markers and Predictive Models for Diagnosis, Immunotherapy and Prognosis in Lung Cancer

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ORIGINAL RESEARCH

Published on 01 Jul 2026

Plasma HERV-K envelopE RNA: a minimally invasive biomarker for lung adenocarcinoma detection and prognostic assessment in the context of conventional serum tumor markers

Fan Bu
Zi-Yan Jin
Zhi-Qiang Ling

doi 10.3389/fimmu.2026.1782414

868 views

ORIGINAL RESEARCH

Published on 10 Jun 2026

CTSL loss leads to anti-PD-1 immunotherapy resistance in lung cancer by suppressing the anti-tumor function of peripheral CD8+ T cells

Ying Wang
Jing Huang
Xueyang Zou
Jiancheng Xu

doi 10.3389/fimmu.2026.1863563

752 views

ORIGINAL RESEARCH

Published on 25 May 2026

Non-invasive radiogenomic mapping of the SMARCAL1-driven ferroptotic niche is associated with longitudinal MRD-negative surveillance in early-stage NSCLC

Zehao Huang
JunDao He
Yue Li
ZhanYu Xu
Huajian Peng
Xiang Gao
HuaFu Zhou
JianJi Guo
Nuo Yang

doi 10.3389/fimmu.2026.1835413

1,569 views

ORIGINAL RESEARCH

Published on 01 May 2026

A machine learning-derived hypoxia- and lactylation-associated gene signature for prognostic stratification and immune landscape characterization in lung adenocarcinoma

Guannan Wang
Yanan Wang
Hongfeng Wu
Hua Huang
Xuanguang Li
Wenhao Zhao
Yongwen Li
Hongyu Liu
Jun Chen

doi 10.3389/fimmu.2026.1720885

1,199 views

ORIGINAL RESEARCH

Published on 24 Apr 2026

Pan-cancer analysis of OSR2 with a focus on underlying mechanisms and therapeutic implications in lung adenocarcinoma

Shijie Liu
Xuan Xiang
Siyu Liu
Wenbei Peng
Zihao Wang
Linlin Ye
Qiong Zhou

doi 10.3389/fimmu.2026.1769446

1,487 views

REVIEW

Published on 20 Apr 2026

The application and challenges of immune checkpoint inhibitors in lung cancer therapy

Bingbing Li
Yuning Ren
Xiaoling Zhang

doi 10.3389/fimmu.2026.1811169

1,845 views
1 citation

ORIGINAL RESEARCH

Published on 16 Apr 2026

Divergent immune and extracellular matrix transcriptional programs underlie poor prognosis in early-stage lung adenocarcinoma

Jyothi Thyagabhavan Mony

doi 10.3389/fimmu.2026.1762224

1,047 views

ORIGINAL RESEARCH

Published on 15 Apr 2026

A fusion model based on tumor and peritumoral CT radiomics for differentiating bronchiolar adenoma from lung adenocarcinoma

Ziqian Zhao
Tengfei Ke
Zeyan Xu
Yong Zhou
Yanwen Dong
Yifan Liu
Jianping Wu
Wenyan Wei
Dan Han
Wen Zhao

doi 10.3389/fonc.2026.1798218

957 views

ORIGINAL RESEARCH

Published on 10 Apr 2026

MRI-based morphological and spatial characteristics of leptomeningeal metastasis: prognostic value in non-small cell lung cancer

Xin Chen
Xueying He
Tianli Zhang
Huiying Li
Cen Chen
Mingmin Huang
Aibin Guo
Tingting Yu
Yu Xie
5 more
Xue Liang

doi 10.3389/fonc.2026.1764407

1,273 views

ORIGINAL RESEARCH

Published on 07 Apr 2026

Adapting federated radiomics models for radiation pneumonitis prediction in patients receiving thoracic radiotherapy with immunotherapy

Zirui Zhu
Meng Yan
Wenhao Ji
Zhen Zhang
Andre Dekker
Leonard Wee
Tian Zhang
Xiaojing Lai

doi 10.3389/fimmu.2026.1793039

1,208 views

ORIGINAL RESEARCH

Published on 07 Apr 2026

Normal tissue complication probability modeling of severe radiation-induced lymphopenia using blood dose for lung cancer patients treated with IMRT and IMPT

Shuting Wang
Tianyuan Dai
Xiaoying Fan
Weijie Li
Wei Huang
Ruozheng Wang
Yong Yin

doi 10.3389/fimmu.2026.1752785

1,370 views

ORIGINAL RESEARCH

Published on 13 Mar 2026

CT-based intratumoral habitat and peritumoral radiomics model to predict spread through air spaces in solid lung adenocarcinoma with diameter ≤ 2 cm: a dual-center study

Guodong Shang
Jia Bian
Ping Wang
Yingjian Song
Shuai Zhao
Ning Dong
Zhongkai Yuan
Xiaonu Peng

doi 10.3389/fonc.2026.1752554

1,528 views

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Frontiers in Immunology

Cancer Immunity and Immunotherapy

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Frontiers in Oncology
- Cancer Immunity and Immunotherapy
- 3.4 impact factor
- 6.6 citescore

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Articles

Plasma HERV-K envelopE RNA: a minimally invasive biomarker for lung adenocarcinoma detection and prognostic assessment in the context of conventional serum tumor markers

CTSL loss leads to anti-PD-1 immunotherapy resistance in lung cancer by suppressing the anti-tumor function of peripheral CD8+ T cells

Non-invasive radiogenomic mapping of the SMARCAL1-driven ferroptotic niche is associated with longitudinal MRD-negative surveillance in early-stage NSCLC

A machine learning-derived hypoxia- and lactylation-associated gene signature for prognostic stratification and immune landscape characterization in lung adenocarcinoma

Pan-cancer analysis of OSR2 with a focus on underlying mechanisms and therapeutic implications in lung adenocarcinoma

The application and challenges of immune checkpoint inhibitors in lung cancer therapy

Divergent immune and extracellular matrix transcriptional programs underlie poor prognosis in early-stage lung adenocarcinoma

A fusion model based on tumor and peritumoral CT radiomics for differentiating bronchiolar adenoma from lung adenocarcinoma

MRI-based morphological and spatial characteristics of leptomeningeal metastasis: prognostic value in non-small cell lung cancer

Adapting federated radiomics models for radiation pneumonitis prediction in patients receiving thoracic radiotherapy with immunotherapy

Normal tissue complication probability modeling of severe radiation-induced lymphopenia using blood dose for lung cancer patients treated with IMRT and IMPT

CT-based intratumoral habitat and peritumoral radiomics model to predict spread through air spaces in solid lung adenocarcinoma with diameter ≤ 2 cm: a dual-center study

Frontiers in Immunology

Cancer Immunity and Immunotherapy

Other participating journals

Frontiers in Oncology

Cancer Immunity and Immunotherapy